Download Name Epigenetics http://learn.genetics.utah.edu/content/epigenetics

Name __________________________________________________
Epigenetics
http://learn.genetics.utah.edu/content/epigenetics/
Epigenetics at a glance
Watch the video “Epigenetics at a glance” Then answer the following question.

Describe the physical state of the genome (tightly wrapped, or relaxed) when
genes are inactive.

How does this affect the PHENOTYPE of an individual?
Gene Control
Click on the link that says “Gene Control” and look at the changes in gene expression
when the DNA is more/ less condensed then answer the following questions.
1. Describe the following characteristics when a gene is active:
o
Is the gene tightly or loosely wound around histones?
o
Are there many or few methyl molecules attached to the gene?
o
Are there many or few acetyl molecules attached to the genes
associated histones?
o
Are there many or few mRNA transcripts?
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2. Describe the following characteristics when a gene is inactive:
o Is the gene tightly or loosely wound around histones?
o
Are there many or few methyl molecules attached to the gene?
o
Are there many or few acetyl molecules attached to the genes
associated histones?
o
Are there many or few mRNA transcripts?
The Epigenome Learns from its experiences.
Click on the link—The epigenome learns from its experiences and then answer the
following questions.
1. True or False. Cell signals play a role in shaping gene expression only during
development.
2. What molecule is primarily responsible for carrying cell signals to DNA?
3. What are the two functions of gene regulatory proteins?
4. Are epigenetic tags passed to daughter cells?
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D) Insights from Identical Twins
Click on the video link “Insights from Identical Twins” watch the video and answer
the questions below.
1. Often, the physical characteristics of genetically identical twins become
increasingly different as they age, even at the molecular level. Explain why
this is so. (use the terms "environment" and "epigenome")
2. Name 3-4 environmental factors that influence the epigenome.
a.
b.
c.
d.
3. What is an imprinted gene? (Hint: there is a link towards the bottom right
hand side of the page)
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E) Nutrition and the Epigenome
1. Explain how the food we eat affects gene expression. GIVE SPECIFIC
EXAMPLES!!!!!!!
2. Can the diets of parents affect their offspring's epigenome? Be specific – talk
about MOM and DAD!
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