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Arabidopsis Cell Division Cycle 20.1 Is Required for Normal Meiotic
Arabidopsis Cell Division Cycle 20.1 Is Required for Normal Meiotic

... CDC20.1 Is Required for Male Fertility in Arabidopsis CDC20.1 and CDC20.2 have distinct expression patterns in somatic and reproductive tissues, whereas the three other genes lack detectable expression and are likely pseudogenes (Kevei et al., 2011). CDC20.1 and CDC20.2 share 99% protein sequence id ...
PCTpc201500834rar1_pap_plantcell 1..16
PCTpc201500834rar1_pap_plantcell 1..16

... CDC20.1 Is Required for Male Fertility in Arabidopsis CDC20.1 and CDC20.2 have distinct expression patterns in somatic and reproductive tissues, whereas the three other genes lack detectable expression and are likely pseudogenes (Kevei et al., 2011). CDC20.1 and CDC20.2 share 99% protein sequence id ...
PCTpc201500834rar1_pap_plantcell 1..16
PCTpc201500834rar1_pap_plantcell 1..16

... CDC20.1 Is Required for Male Fertility in Arabidopsis CDC20.1 and CDC20.2 have distinct expression patterns in somatic and reproductive tissues, whereas the three other genes lack detectable expression and are likely pseudogenes (Kevei et al., 2011). CDC20.1 and CDC20.2 share 99% protein sequence id ...
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PDF

... showed only weak expression at the basal pole of gnom, whereas the suspensor signal also seen in wild type is maintained (Fig. 1C,G). These data indicate that the root pole is not properly established in gnom. As cotyledon formation in gnom is also impaired, we next tested whether apical markers wer ...
Identification of new components involved in shoot gravitropism in
Identification of new components involved in shoot gravitropism in

... (WT) level. Most of the suppressors were isolated from different seed pools, and they show various degrees of gravitropic response as compared to WS (wild type) and scr1. Therefore, it is reasonable to predict that each suppressor represents a different mutation. Each mutation should point to a spe ...
Establishing neuroblast-specific gene expression in the Drosophila
Establishing neuroblast-specific gene expression in the Drosophila

... neuroectodermal clusters and neuroblasts. The neuroectoderm can be divided into 7 rows (1-7, from anterior to posterior) and 3 columns (medial, intermediate and lateral), based on boundaries of gene expression and the arrangement of neuroblasts (Campos-Ortega and Hartenstein, 1985; Doe, 1992; Broadu ...
Interactions between the otitis media gene, Fbxo11, and p53 in the
Interactions between the otitis media gene, Fbxo11, and p53 in the

... media (Hardisty et al., 2003; Hardisty-Hughes et al., 2006), Jeff homozygotes display developmental epithelial abnormalities including underdeveloped lungs (Tateossian et al., 2009). The TGF-β signalling pathway is integral for normal lung development with all three TGF-β isoforms expressed in embry ...
Changes in retinoic acid signaling alter otic patterning
Changes in retinoic acid signaling alter otic patterning

... Otic defects generated by changes in RA signaling are considered mostly secondary consequences due to changes in Fgf signaling, because hindbrain patterning is disturbed in RA gain- and loss-offunction studies. In embryos with no RA signaling, such as mouse Aldh1a2 mutants, expression of Fgf3, which ...
The P53 pathway and metabolism: implications in tissue
The P53 pathway and metabolism: implications in tissue

... p53 and Mdm2 are involved in a ...
The role of Grainy head in epithelial tissue growth
The role of Grainy head in epithelial tissue growth

... The grainy head (grh) gene family encodes an important group of transcription factors that play a remarkably conserved role in epithelial organ development, epithelial barrier formation and epithelial repair upon damage in different organisms. The regulation and molecular targets of Grh are numerous ...
The one-eyed pinhead gene functions in mesoderm and endoderm
The one-eyed pinhead gene functions in mesoderm and endoderm

... found to be linked to oep. Since RAPD markers are strain-specific and therefore not informative in all mapping crosses, a sequence-tagged site (STS) marker for the 15AH.500 locus was generated by cloning and sequencing the RAPD fragment and synthesizing primers specific for that sequence (primer WTZ ...
Mutations affecting development of the notochord in zebrafish
Mutations affecting development of the notochord in zebrafish

... Johnson et al., 1994a; Roelink et al., 1994). Other peptide growth factors, such as bone morphogenic proteins BMP-2 and BMP-7 have also been found to be expressed in the notochord (Lyons et al., 1995). Taken together these data point to the importance of the notochord, not only for the structural in ...
sidecar pollen, an Arabidopsis thaliana male
sidecar pollen, an Arabidopsis thaliana male

... species (such as Arabidopsis and maize) this mitosis takes place before pollen is released from anthers. Mature Arabidopsis pollen therefore contains three cells – one vegetative cell and two sperm cells enclosed within the cytoplasm of the vegetative cell. Pollen offers an excellent system with whi ...
The control of shoot branching: an example of plant information
The control of shoot branching: an example of plant information

... transport pathways or canals between the source and the sink. In the right developmental context, vascular strands differentiate from the files of cells along which auxin transport was canalized. Because of this close association with vascular development, canalization has been most studied in the c ...
Creating order from chaos: epigenome dynamics in
Creating order from chaos: epigenome dynamics in

... Finally, it is worth considering variation in selection against TE proliferation at the level ...
Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail
Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail

... cell invagination to form the mesoderm (Ip and Gridley, 2002; Leptin, 1999; Stathopoulos and Levine, 2002). In dorsal, twist or snail mutants, no ventral invagination occurs and no mesodermal tissues are formed. Twist is a basic helix-loophelix transcription factor and acts as a co-activator for Dor ...
A survey on computational methods for enhancer and
A survey on computational methods for enhancer and

... and negative examples for modeling the general features of enhancers and enhancer targets. As a result, different studies have used a variety of ways to define “gold-standard” enhancers and enhancer targets for training their methods. A lot of these “gold-standard” examples are either not experiment ...
Mouse Lefty2 and Zebrafish Antivin Are Feedback
Mouse Lefty2 and Zebrafish Antivin Are Feedback

... The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on chromosome 1 (Meno et al., 1997). To examine the role of lefty2 in gastrulation and L–R asymmetry, we generated mutant mice deficient in lefty2. To inactivate lefty2, we constructed a t ...
Transvection Is Common Throughout the Drosophila
Transvection Is Common Throughout the Drosophila

... et al. 2008). Transvection may also be modified by zeste (Jack and Judd 1979), which has been found to be required for some examples of transvection (Kaufman et al. 1973; Gelbart and Wu 1982; Leiserson et al. 1994), and may facilitate physical interactions between alleles at some loci (Benson and Pir ...
WUSCHEL signaling functions in interregional communication
WUSCHEL signaling functions in interregional communication

... CLV1::WUS; wus plants. (A–H) DIC microscopy images of ovule development in CLV1::WUS plants (A,C,E,G) and CLV1::WUS; wus (B,D,F,H) plants. (A,B) Stage 1-II, ovule primordia have grown out. The megaspore mother cell is apparent in the subepidermal layer. (C,D) In CLV1::WUS ovules the inner integument ...
Cross talk between the sporophyte and the
Cross talk between the sporophyte and the

... highly synchronized morphogenesis of the maternal sporophyte surrounding the gametophyte, since megagametogenesis is severely perturbed in most of the known sporophytic ovule development mutants. Which are the messenger molecules involved in the haploid-diploid dialogue? And furthermore, is this one ...
Cotyledon organogenesis - Journal of Experimental Botany
Cotyledon organogenesis - Journal of Experimental Botany

... The evolution of cotyledony Cotyledons exist across the plant kingdom in gymnosperms, monocots, and eudicots. A distinction should be made here between dicots as a group, containing all plants with two cotyledons, where the term dicot is used as a form of morphology only, and the eudicots, a monophy ...
Huntingtin function during zebrafish (Danio rerio) development
Huntingtin function during zebrafish (Danio rerio) development

... functions of these proteins have therefore become a focus of investigation as potential pathogenic pathways. Here, synthetic antisense morpholinos have been used to inhibit the translation of huntingtin protein during early zebrafish development. The results obtained show the effects of huntingtin l ...
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... considered two separate conditions. Therefore, some debate remains in the clinic on whether sirenomelia and CD are separate conditions or just different degrees of the same multisystemic malformation [12,24]. Besides clinical data, experimental data in mouse indicate a genetic origin for sirenomelia ...
Pax1, Pax9, Vertebral column, Chondrogenesis, Proliferation
Pax1, Pax9, Vertebral column, Chondrogenesis, Proliferation

... small discs; Ab, abnormal discs with granular zone and abnormal folding; Og, overgrown disc; N, normal disc) and late pupal (pharate adults) and adult phenotypes (*, late pupal lethal with typical dco3 phenotype (swollen tarsi, or swollen tarsi with head defects); LP, late pupal lethal with normal p ...
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Epigenetics in stem-cell differentiation

Embryonic stem cells are capable of self-renewing and differentiating to the desired fate depending on its position within the body. Stem cell homeostasis is maintained through epigenetic mechanisms that are highly dynamic in regulating the chromatin structure as well as specific gene transcription programs. Epigenetics has been used to refer to changes in gene expression, which are heritable through modifications not affecting the DNA sequence.The mammalian epigenome undergoes global remodeling during early stem cell development that requires commitment of cells to be restricted to the desired lineage. There has been multiple evidence suggesting that the maintenance of the lineage commitment of stem cells are controlled by epigenetic mechanisms such as DNA methylation, histone modifications and regulation of ATP-dependent remolding of chromatin structure. Based on the histone code hypothesis, distinct covalent histone modifications can lead to functionally distinct chromatin structures that influence the fate of the cell.This regulation of chromatin through epigenetic modifications is a molecular mechanism that will determine whether the cell will continue to differentiate into the desired fate. A research study performed by Lee et al. examined the effects of epigenetic modifications on the chromatin structure and the modulation of these epigenetic markers during stem cell differentiation through in vitro differentiation of murine embryonic stem (ES) cells.
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