Science at the heart of medicine Eric Bouhassira, Ph.D.
... Dr. Bouhassira obtained his Ph.D. in 1989 from the University of Paris and has spent most of his career at Albert Einstein College of Medicine, where he is now the Ingeborg and Ira Leon Rennert Professor of Stem Cell Biology and Regenerative Medicine in the departments of medicine and of cell biolog ...
... Dr. Bouhassira obtained his Ph.D. in 1989 from the University of Paris and has spent most of his career at Albert Einstein College of Medicine, where he is now the Ingeborg and Ira Leon Rennert Professor of Stem Cell Biology and Regenerative Medicine in the departments of medicine and of cell biolog ...
Binary Switches in Gene Expression: The Histone Code
... Misregulation of the “on” and “off” dynamics of histone modifications can lead to diseases such as cancer. Histone acetylation and methylation prevent DNA from coiling tightly, allowing associated genes to be expressed. The opposite processes, deacetylation and demethylation, allow the DNA to coil t ...
... Misregulation of the “on” and “off” dynamics of histone modifications can lead to diseases such as cancer. Histone acetylation and methylation prevent DNA from coiling tightly, allowing associated genes to be expressed. The opposite processes, deacetylation and demethylation, allow the DNA to coil t ...
Dual function of histone H3K76 methylation in cell cycle regulation
... structure with an emphasis on posttranslational histone modifications (PTMs) and the enzymes that are responsible for them. After dissecting the repertoire of PTMs in two life cycle stages in trypanosomes, we focused on methylation of histone H3 on lysine 76 in the histone core, which is mediated by ...
... structure with an emphasis on posttranslational histone modifications (PTMs) and the enzymes that are responsible for them. After dissecting the repertoire of PTMs in two life cycle stages in trypanosomes, we focused on methylation of histone H3 on lysine 76 in the histone core, which is mediated by ...
Regulation and Expression of Aldehyde Dehydrogenase in Normal
... Aberrant changes of DNA methylation, histone modification and chromatin compartments are commonly associated with the progression of human cancers. Hypermethylation of CpG islands is the most well categorised epigenetic change to occur in tumours. Many CpG islands associated with transcription of a ...
... Aberrant changes of DNA methylation, histone modification and chromatin compartments are commonly associated with the progression of human cancers. Hypermethylation of CpG islands is the most well categorised epigenetic change to occur in tumours. Many CpG islands associated with transcription of a ...
PowerPoint
... Uses histone deacetylase (HDAC) inhibitors to prevent the deacetylation of histones bound to tumor suppressor genes. ...
... Uses histone deacetylase (HDAC) inhibitors to prevent the deacetylation of histones bound to tumor suppressor genes. ...
Debbie Spector
... Deborah Spector, Ph.D. Research Interests Association of cytomegalovirus with atherosclerosis Mechanisms governing hearing loss as a result of congenital cytomegalovirus infection Development of herpesvirus vaccines Exploiting autophagy as an antiviral ...
... Deborah Spector, Ph.D. Research Interests Association of cytomegalovirus with atherosclerosis Mechanisms governing hearing loss as a result of congenital cytomegalovirus infection Development of herpesvirus vaccines Exploiting autophagy as an antiviral ...
Name: Date: Class Period: Video questions: Video 1: Gene
... What is a regulatory gene? What is an example of a regulatory sequence? What is lactose? What does it mean when a gene is expressed? What is the function of the TATA box? What is the function of an operator sequence? Why would bacteria want to make enzymes (proteins) that break down lactose only whe ...
... What is a regulatory gene? What is an example of a regulatory sequence? What is lactose? What does it mean when a gene is expressed? What is the function of the TATA box? What is the function of an operator sequence? Why would bacteria want to make enzymes (proteins) that break down lactose only whe ...
basic characterisation of hiPSC.
... Expression of key endogenous pluripotency-associated genes Evidence of transgene silencing ...
... Expression of key endogenous pluripotency-associated genes Evidence of transgene silencing ...