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Chapter 4 Pre-Test (A) Multiple Choice Identify the choice that best completes the statement or answers the question. ____ 1. Which of the following types of nitrogenous bases are present in DNA? a. cytosine, uracil, adenine, and thymine b. adenine, guanine, uracil, and cytosine c. thymine, cytosine, guanine, and uracil d. adenine, thymine, guanine, and cytosine ____ 2. In a DNA molecule, the amount of adenine is equal to the amount of a. uracil. b. guanine. c. thymine. d. cytosine. ____ 3. A segment of a DNA molecule contains 34% C. What will be the proportion of G and T in this segment of DNA? a. G = 34% and T = 16% b. T = 34% and G = 16% c. G = 34% and T = 34% d. T = 16% and G = 16% ____ 4. In human DNA, if the percentage of adenine in a cell is 31%, what is the expected percentage of guanine? a. 19% b. 31% c. 38% d. 62% ____ 5. Use the diagram above to answer the next question. Consider the following segment of a mRNA strand: GAG CAU UAU Which of the following is the sequence of amino acids that correspond with this mRNA strand? a. leucine-valine-isoleucine b. leucine-histidine-tyrosine c. glutamate-valine-tyrosine d. glutamate-histidine-tyrosine ____ 6. Use the diagram above to answer the next question. Identify structure 3 in the polymer. a. ribose b. glucose c. phosphate d. deoxyribose ____ 7. Use the diagram above to answer the next question. Which of the following labeled structures make up a nucleotide? a. Structures 1 and 2 b. Structures 1, 2, and 3 c. Structures 1, 2, and 4 d. Structures 2, 3, and 4 ____ 8. Use the diagram above to answer the next question. Structures 3 and 4 make up a. the hydrogen bonds. b. the nitrogenous bases. c. the amino acid backbone. d. the sugar-phosphate backbone. ____ 9. Use the diagram above to answer the next question. What does structure 1 and 2 illustrate? a. a nucleotide b. antiparallel DNA strands c. complementary base pairing d. alternating sugar and phosphate ____ 10. Which of the following statements describes how the two DNA strands are held together? a. by covalent bonds between the pentose sugars b. by hydrogen bonds between the nitrogenous bases c. by hydrogen bonds between the pentose sugar and the phosphate group d. by covalent bonds between the nitrogenous base and the phosphate group ____ 11. What role do ribosomes play in protein synthesis? a. It transcribes the mRNA. b. It brings amino acids to the tRNA. c. It provides the binding site for mRNA and tRNA. d. It forms hydrogen bonds between the complementary base pairs of DNA and mRNA. ____ 12. Use the diagram above to answer the next question. The products synthesized at structure D are composed of long chains of a. lipids. b. nucleotides. c. amino acids. d. carbohydrates. ____ 13. An anticodon consists of a sequence of three nitrogenous bases on the a. DNA. b. rRNA. c. rRNA. d. tRNA. ____ 14. Consider the following segment of a mRNA strand: AAC GCA UGG Which of the following sequences lists the anticodons that are complementary to this strand? a. TTG CGT ACC b. UUG CGU ACC c. UUC GCU ACC d. AAC GCA UGG ____ 15. DNA is a polymer made up of a. nucleotides. b. amino acids. c. nucleic acids. d. carbohydrates. ____ 16. Which type of bonds are broken by helicase in DNA replication? a. ionic bonds b. peptide bonds c. covalent bonds d. hydrogen bonds ____ 17. Which of the following statements describes DNA? I II III a. b. c. d. is shaped like a double helix has thymine and deoxyribose is a double stranded nucleic acid I and II only I and III only II and III only I, II, and III ____ 18. Which of the following molecules make up the backbone of DNA? a. phosphate and thymine b. ribose sugar and phosphate c. adenine and deoxyribose sugar d. deoxyribose sugar and phosphate ____ 19. What enzyme is responsible for joining a purine to a pyrimidine during replication? a. ligase b. helicase c. RNA polymerase d. DNA polymerase ____ 20. If the sequence of bases on one DNA strand is GTACCGATA, what is the complementary sequence of bases on the other DNA strand? a. GTACCGATA b. GAUGGCUAU c. TATCGGTAC d. CATGGCTAT ____ 21. Which of the following pairs are examples of complementary base pairing? I II III a. b. c. d. uracil and thymine thymine and adenine cytosine and guanine I and II only I and III only II and III only I, II, and III ____ 22. In the process of genetic engineering, recombinant DNA is produced by combining genetic material from two different sources. For this technique, genetic engineers are especially interested in a specific group of enzymes called restriction enzymes. These enzymes are preferred because they a. cut DNA from their 5’ or 3’ ends. b. join the DNA fragments at 3’ ends. c. join the DNA fragments at 5’ ends. d. cut DNA at specific sites within the DNA. ____ 23. Use the diagram above to answer the next question. What component of this molecule causes it to have a low pH? a. the purine b. the pyrimidine c. the pentose sugar d. the phosphate group ____ 24. Which of the following explains why mistakes in DNA replication are not common? a. helicase repairs any mistakes during replication b. helicase does not zip up the double helix if there is a mistake c. ligase will cleave out the mistake before DNA winds up into a double helix d. DNA polymerase proofreads and corrects any mistakes in the pairing of nucleotides ____ 25. During replication, the DNA sequence CATGGA is copied as CATGCA. This is an example of a. a mutagen. b. a point mutation. c. a transcription error. d. a frameshift mutation. Chapter 4 Pre-Test (A) Answer Section MULTIPLE CHOICE 1. ANS: OBJ: TOP: 2. ANS: OBJ: TOP: 3. ANS: OBJ: TOP: 4. ANS: OBJ: TOP: 5. ANS: OBJ: TOP: 6. ANS: OBJ: TOP: 7. ANS: OBJ: TOP: 8. ANS: OBJ: TOP: 9. ANS: OBJ: TOP: 10. ANS: OBJ: TOP: 11. ANS: OBJ: TOP: 12. ANS: OBJ: TOP: 13. ANS: OBJ: TOP: 14. ANS: OBJ: TOP: 15. ANS: D PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure C PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure A PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure A PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: DNA Structure and Gene Expression 4.3 KEY: Gene Expression D PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure C PTS: 1 DIF: DNA Structure and Gene Expression 4.1 KEY: DNA Structure B PTS: 1 DIF: DNA Structure and Gene Expression 4.2 KEY: DNA Replication C PTS: 1 DIF: DNA Structure and Gene Expression 4.3 KEY: Gene Expression C PTS: 1 DIF: DNA Structure and Gene Expression 4.3 KEY: Gene Expression D PTS: 1 DIF: DNA Structure and Gene Expression 4.3 KEY: Gene Expression B PTS: 1 DIF: DNA Structure and Gene Expression 4.3 KEY: Gene Expression A PTS: 1 DIF: K REF: 4 LOC: B7-1 U REF: 4 LOC: B7-1 HMP REF: 4 LOC: B7-1 U REF: 4 LOC: B7-1 U REF: 4 LOC: B7-1 U REF: 4 LOC: B5-1 U REF: 4 LOC: B5-1 U REF: 4 LOC: B7-1 U REF: 4 LOC: B7-1 U REF: 4 LOC: B5-1 K REF: 4 LOC: B7-1 U REF: 4 LOC: B7-1 K REF: 4 LOC: B7-1 U REF: 4 LOC: B7-3 K REF: 4 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: ANS: OBJ: TOP: DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: U DNA Structure and Gene Expression 4.2 KEY: DNA Replication D PTS: 1 DIF: K DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: K DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: U DNA Structure and Gene Expression 4.2 KEY: DNA Replication D PTS: 1 DIF: U DNA Structure and Gene Expression 4.1 KEY: DNA Structure C PTS: 1 DIF: U DNA Structure and Gene Expression 4.2 KEY: DNA Replication D PTS: 1 DIF: U DNA Structure and Gene Expression 4.5 KEY: DNA Cloning D PTS: 1 DIF: HMP DNA Structure and Gene Expression 4.1 KEY: DNA Structure D PTS: 1 DIF: U DNA Structure and Gene Expression 4.4 KEY: Gene Mutations and Cancer B PTS: 1 DIF: U DNA Structure and Gene Expression 4.4 KEY: Gene Mutations and Cancer LOC: B7-1 REF: 4 LOC: B5-1 REF: 4 LOC: B7-1 REF: 4 LOC: B7-1 REF: 4 LOC: B5-1 REF: 4 LOC: B7-1 REF: 4 LOC: B7-1 REF: 4 LOC: B6-1 REF: 4 LOC: B7-1 REF: 4 LOC: B8-2 REF: 4 LOC: B8-2