* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Organism sorting rules
Epigenetics of neurodegenerative diseases wikipedia , lookup
Transposable element wikipedia , lookup
Point mutation wikipedia , lookup
Biology and consumer behaviour wikipedia , lookup
Genomic library wikipedia , lookup
Saethre–Chotzen syndrome wikipedia , lookup
Ridge (biology) wikipedia , lookup
Neuronal ceroid lipofuscinosis wikipedia , lookup
Gene therapy of the human retina wikipedia , lookup
Copy-number variation wikipedia , lookup
Epigenetics of diabetes Type 2 wikipedia , lookup
Public health genomics wikipedia , lookup
Genomic imprinting wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Epigenetics of human development wikipedia , lookup
Nutriepigenomics wikipedia , lookup
Pathogenomics wikipedia , lookup
Gene therapy wikipedia , lookup
Minimal genome wikipedia , lookup
Therapeutic gene modulation wikipedia , lookup
Genetic engineering wikipedia , lookup
Genome editing wikipedia , lookup
Genome (book) wikipedia , lookup
Gene expression programming wikipedia , lookup
Gene desert wikipedia , lookup
History of genetic engineering wikipedia , lookup
Gene nomenclature wikipedia , lookup
Gene expression profiling wikipedia , lookup
The Selfish Gene wikipedia , lookup
Helitron (biology) wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Genome evolution wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
Organism sorting rules The genomic context view displays a limited portion of a subset of genomes, focussed on a reference gene belonging to a reference organism. The top row shows the genomic context in this reference organism, around the centrally located reference gene. Genes (represented as arrow-shaped boxes) are colored according to the cluster they belong to. Each row below the reference genome shows a portion of another organism's genome, centered on the gene belonging to the same cluster as the reference gene (these genes are considered as being orthologs). The order in which the organisms are drawn, from top to bottom, is determined by a « proximity score» accounting for the number of conserved orthologs (i.e. genes belonging to the same cluster) in the neighbourhood of the ortholog of the reference gene. This score is computed as follows (see the figure below): each gene in the neighbourhood of the ortholog of the reference gene is awarded 2 points if it is an ortholog of (i.e. belongs to the same cluster as) one of the genes in the neighbourhood of the reference gene, and an additional point if it is at the same distance from the reference gene in the two organisms. Thus, the proximity score of an organism is the sum of the points of every gene in the neighbourhood of the ortholog of the reference gene. Figure : Sorting example