Download Bell work Objectives: DNA replication DNA Replication

DNA replication
2.28.14
Bell work
• Finish the sentence:
DNA is important to
forensic science
because…
Objectives:
I will:
• Model DNA replication
with my paper DNA
model.
• Describe protein
synthesis, and
successfully answer
questions about DNA
and protein synthesis.
DNA Replication
• DNA replication is the
process of creating a
copy of DNA in
preparation for cell
division.
• http://www.youtube.co
m/watch?v=yqESR7E
4b_8 (1:33)
Try it: DNA Replication
Step 1: After you have completed your DNA
keychain, label the bases on the paper model
with A, T, G, or C exactly as they are on your
keychain from the bottom to the top.
Cut in half
S
P
A
T
C
G
Step 2: “Unzip” the paper model by cutting it in
half longwise and glue the pieces in the correct
location on your worksheet so the bases match
up correctly.
Step 3: Label the empty boxes
using A, T, G, or C and then
color them using the colors on
your DNA Guide. Remember
to match the bases correctly!
A–T
T–A
G–C
C-G
Step 4: Answer the questions
on the back of your worksheet.
http://stemcells.nih.gov/StaticResources/info/scireport/images/figurea6.jpg
1
What’s next after DNA
replication?
Take notes on
your own paper, I
know… gasp!
How are proteins
produced?
• 1-RNA Transcription
Proteins
are
produced!
• 2- RNA Processing
• 3- mRNA Transport
• 4-Protien Translation
RNA -Transcription:
• mRNA ( messenger
ribonucleic acid) copies the
code from the DNA and
carries the “message” to
the RNA
• Transcribing the
code
Protein Translation:
•
•
•
Translation is the synthesis of
proteins directed by a mRNA
template at a ribosome.
mRNA is “read” in 3 letter
triplets (codons) to create a
polypeptide chain of amino
acids.
tRNA (transfer RNA) brings the
amino acids to the ribosomes
& assembles the protein.
• Cracking the Code
2
Questions
1. How do the bases in DNA pair up?
T
A - _____
C
A
G
G - _____
T - ______
C - ______
2. Compare your two “new” DNA molecules (the ones you did on the front)
to your actual keychain. How does the order of the bases they compare?
Going Further ...
As we discussed in class, the DNA molecules consists of nitrogen base pairs.
The order of the pairs determines the genetic code, which controls protein
synthesis or the production of proteins.
6. What do we call a set of three nitrogen bases?
___________________ or ____________________
The order of the bases should match the order on your keychain.
7. What organelle in a cell contains the DNA? ___________________
Mutation
3. What do we call a change in a gene or chromosome? ________________
8. What organelle is the protein factory in a cell? __________________
4. What two cell division processes use DNA replication?
9. How does the genetic code get to a ribosome? _______________________
Meiosis
Mitosis
_________________
& _________________
5. What is created by each of the processes in #4?
Meiosis – Sex Cells
Mitosis – Daughter Cells
10. What type of RNA assembles the proteins? ________________________
11. What are the building blocks of proteins? ______________________
12. What is another term for a protein?
____________________ chain (a natural polymer)
Closing Question
• What is the purpose of DNA replication?
3