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Neuron Physiology Notes-The Nerve Impulse _________________-nerve impulses which are sent by a change in electrical charge in the cell membrane. ______ (Na+) highly concentrated outside of cells ___________ (K+) highly concentrated inside cells _________________________- Ions move from high concentration to a low concentration passively ______________ pumps moves ions actively using ATP Active Pump Creating a Resting Potential _________________________ – open and close – let ions through ________________________ – Ions move against a gradient – Use ATP to work _________________________ – Ions move with the gradient – Ions move from _________ to low concentration Passive Pump Stages of a Nerve Impulse STAGE 1) Neuron at “resting membrane potential” is polarized with a resting potential of (-70 mv) 2.) Neuron is stimulated by the influx of a neurotransmitters that causes sodium channels to open. Sodium moves inward causing neuron to depolarize. (-62mv) 3.) Threshold is reached when enough sodium enters the neuron to change the potential to (-55mv) which causes “trigger zone” to allow even more sodium into the neuron. Action Potential occurs, message transmitted. 4.) Neuron continues to depolarize as sodium channels further open. 5.) Potassium channels open and potassium diffuses out so membrane can be repolarized. Occasionally the membrane is hyperpolarized and then returns to polarized state. DRAWING of Neuron Graph Saltatory nerve impulse conduction Myelinated vs. unmyelinated axons Speed of nerve impulse All or None Response Refractory period