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CHEMICAL SENSES I. TRUE or FALSE. Circle the appropriate letter. T F 1. Gustatory receptors are neurons. T F 2. The vagus nerve conveys gustatory signals originating from the oropharynx and upper esophogus. T F 3. The thalamic terminations of the ascending taste pathways lie in the ventral nuclear group, near the termination of ascending trigeminothalamic fibers. T F 4. All primary gustatory afferents synapse in the nucleus of the solitary tract. T F 5. Cortical neurons responsive to gustatory stimuli can be found near the tongue area of the primary somatic sensory cortex and in the insula. T F 6. Axons of the olfactory nerve arise from receptor cells in the olfactory mucosa. T F 7. As in the visual and auditory modalities, olfactory signals must synapse in the thalamus before reaching the cerebral cortex. T F 8. The cortex of the medial temporal lobe that overlies the amygdala is a major target of the olfactory tract. T F 9. A patient who complains that food suddenly tastes bland may actually have damage to the olfactory pathways. T F 10. Like other neurons, olfactory receptors are never generated in adulthood. T F 11. Individual gustatory receptor cells respond in association with more than one of the primary gustatory qualities (sweet, salty, sour, bitter). T F 12. The nucleus of the solitary tract contains secondary sensory neurons for both taste and viscerosensory pathways. II. MULTIPLE CHOICE. Circle every correct answer. There may be more than one correct answer per question. 1. Taste signals from the anterior two-thirds of the tongue reach the brain after traveling in a. b. c. d. e. the 7th cranial nerve the solitary tract the hypoglossal nerve the facial (intermediate) nerve the glossopharyngeal nerve 2. The gustatory sensations of "sharp," "spicy" and "piquant" most likely reflect afferent activity in a. b. c. d. e. cranial nerve V cranial nerve VII cranial nerve IX cranial nerve X cranial nerve XII 3. Gustatory receptor cells a. b. c. d. e. are neurons disappear if the axons innervating them are cut are replaced about every ten days are grouped together in taste buds bear microvilli basally, at their point of contact with nerve fibers innervating them 4. An axon innervating a taste bud on the posterior third of the tongue a. b. c. d. e. has its cell body in the facial nucleus of the brainstem has its cell body in a cranial-nerve ganglion enters the brainstem with the glossopharyngeal nerve probably innervates one of the circumvallate papillae synapses centrally in the nucleus of the solitary tract 5. Transduction in the olfactory system occurs a. after odorant molecules pass through perforations in the skull to reach the olfactory bulb b. after odorant molecules are dissolved in the mucous layer of the olfactory neuroepithelium c. through interactions between odorant molecules and receptor molecule on the cilia and microvilli of olfactory receptor cells d. in non-neural receptor cells that do not generate action potentials e. in the primary olfactory cortex 6. Seizures preceded by the sensation of an unpleasant odor usually originate from the vicinity of a. b. c. d. e. the uncus the amygdala the olfactory mucosa the cingulate gyrus the nucleus of the solitary tract 7. The olfactory nerve (cranial nerve I) contains the axons of a. b. c. d. e. sustentacular (supporting) cells of the olfactory epithelium receptor cells of the olfactory epithelium tufted cells of the olfactory bulb mitral cells of the olfactory bulb granule cells of the olfactory bulb 8. Which of the following constitute major output targets of the olfactory bulb? a. b. c. d. e. phylogenetically old, simple parts of the cerebral cortex the putamen elements of the limbic system the representation of the nose on the postcentral gyrus the amygdala 9. Which of the following structures or neural elements can be found within the olfactory bulb? a. b. c. d. e. cilia of olfactory receptor cells axon terminals of olfactory receptor cells glomeruli mitral cells inhibitory interneurons 10. Which of the following cell types are second order neurons in the olfactory system? a. b. c. d. e. bipolar neurons of the olfactory epithelium cells in the nucleus of the solitary tract neurons of the amygdaloid complex mitral cells of the olfactory bulb neurons of the olfactory cortex CHEMICAL SENSES I. True or False 1. 2. 3. 4. 5. 6. F T T T T T II. Multiple Choice 7. F 8. T 9. T 10. F 11. T 12. T 1. 2. 3. 4. 5. a, b, d a b, c, d b, c, d, e b, c 6. a, b 7. b 8. a, c, e 9. b, c, d, e 10. d