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Genetics Course Outcome Summary Course Information Organization Developers Development Date Course Number Potential Hours of Instruction Total Credits South Central College Renee Krohne and Sue Steck 1/5/2011 BIOL 211 80 4 Description This is an introductory Genetics course which covers the study of biologically inherited traits. It will emphasize Mendelian genetics as well as molecular genetics. Students will explore classical, population and molecular genetics. Students will learn genetics through lecture, solving genetics problems and demonstrating concepts from lecture through laboratory experimentation. (Prerequisites: General Biology I, General Biology II, Chemistry 121) MNTC area 3 Types of Instruction Instruction Type Lecture Lab Contact Hours Credits 48 32 3 1 Prerequisites General Biology I General Biology II Chemistry 121 Exit Learning Outcomes Core Abilities A. B. C. D. E. Foundations and skills for lifelong learning Teamwork and problem-solving Analysis and inquiry Critical and creative thinking skills Written and oral communication External Standards Goal 3. NATURAL SCIENCES To improve students' understanding of natural science principles and of the methods of scientific inquiry, i.e., the ways in which scientists investigate natural science phenomena. 3.a. Demonstrate understanding of scientific theory. 3.b. Formulate and test hypotheses by performing laboratory, simulation, or field experiments in at least two of the natural science disciplines. One of these experimental components should develop, in greater depth, student's laboratory experience in the collection of data, its statistical and graphical analysis, and an appreciation of its sources of error and uncertainty. 3.c. Communicate their experimental findings, analyses, and interpretations both orally and in writing. 3.d. Evaluate societal issues from a natural science perspective, ask questions about the evidence presented, and make informed judgements about science-related topics and policies. Competencies 1. 2. 3. 4. 5. 6. Develop an understanding of Mendelian genetics. Learning Objectives a. Discuss how the monohybrid cross reveals how one trait is transmitted from generation to generation. b. Explain how Mendel's dihybrid cross revealed his fourth postulate: Independent assortment. c. Describe how the trihybrid cross demonstrates that Mendel's principles apply to inheritance of multiple traits. d. Demonstrate knowledge of transmission genetics by solving genetics problems. e. Analyze a pedigree to predict how traits are inherited. Describe the processes of mitosis and meiosis. Learning Objectives a. List and describe the stages of mitosis b. List and describe the stages of meiosis c. Compare and contrast mitosis and meiosis in regard to their purposes d. Compare and contrast mitosis and meiosis in regard to when each occurs Describe extensions of Mendelian genetics. Learning Objectives a. Describe how alleles alter phenotypes in different ways. b. Explain Dominance, codominance, and incomplete dominance. c. Explain why phenotypes are often affected by more than one gene. d. Explain pleiotropy and provide examples. e. Explain X-linkage. f. Provide examples of how phenotypic expression is not always a direct reflection of genotype. Explain chromosome mapping in eukaryotes. Learning Objectives a. Describe how crossing over serves as the basis of determining the distance between genes during chromosome mapping. b. Determine the gene sequence in Maize using analysis of multiple crossovers during mapping. c. Describe how linkage analysis and mapping can be performed in haploid organisms. d. Demonstrate how gene mapping is possible using molecular biology. Identify the sex chromosomes and how they determine sexual characteristics. Learning Objectives a. Describe how the Y chromosome determines maleness. b. Explain how excessive expression of X-linked genes is prevented. c. Discuss differences in sex determination between humans, fruit flies and reptiles. Describe extranuclear inheritance in chloroplasts and mitochondria. Learning Objectives 7. 8. 9. 10. 11. 12. a. Identify the sources of DNA for extranuclear inheritance b. Explain the molecular organization of mitochondrial and chloroplast DNA c. Describe human disorders caused by mutations in mitochondrial DNA d. Contrast the maternal effect with biparental inheritance Describe the structure of DNA Learning Objectives a. Describe the molecular structure of deoxyribonucleic acid. b. Explain how DNA is organized into chromosomes. Explain the process of DNA replication and recombination Learning Objectives a. Describe the process of semiconservative replication in eukaryotes b. Describe the process of replication in prokaryotes c. Identify enzymes which play a role in DNA replication and recombination d. Explain analytical techniques which have been useful to the investigation of DNA and RNA Describe recombinant DNA technology. Learning Objectives a. Describe the basic steps involved in recombinant DNA and the uses of this technology. b. Describe the roles restriction enzymes and vectors play in recombinant DNA technology. c. Explain how genes can be transferred to eukaryotic cells. d. Describe how polymerase chain reaction makes DNA copies without host cells. e. Describe the genomic library and its role in cloning. f. Describe the various methods for sequencing DNA. g. Explain how recombinant DNA technology has revolutionized genome analysis. Describe the process of protein synthesis. Learning Objectives a. Describe the process of transcription. b. Describe the process of translation. c. Explain how transcription and translation differ between prokaryotes and eukaryotes. d. List some conditions that may occur if there are errors in the process of translation. Describe the role of genetics in cancer formation. Learning Objectives a. Identify cancer as a group of genetic diseases caused by mutations. b. Identify the cellular functions which when altered can lead to cancer. c. Recognize the role viruses have in contributing to cancer development. d. Recognize the role environmental agents have in contributing to cancer development. Demonstrate safe laboratory practices. Learning Objectives a. Be aware of any hazardous materials that may be used during experiments b. Handle chemicals and equipment in a safe manner