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Topic 4 Jeopardy! 4.1 Basics 4.2 Meiosis 3.3/3.4/3.5 4.3 DNA / RNA Monohybrid Protein 4.4 Biotechnol ogy Q $100 Q $100 Q $100 Q $100 Q $100 Q $200 Q $200 Q $200 Q $200 Q $200 Q $300 Q $300 Q $300 Q $300 Q $300 Q $400 Q $400 Q $400 Q $400 Q $400 Q $500 Q $500 Q $500 Q $500 Q $500 Genetics SL $100 Question 4.1 Basics In the following diagram, which pair represents homologous chromosomes? $100 Answer 4.1 Basics 4 & 6 are homologous chromosomes $200 Question 4.1 Basics What is the cause of sickle-cell anemia? 2 points $200 Answer 4.1 Basics • A change to the base sequence of a hemoglobin gene • DNA changes from GAG changes to GTG • mRNA changes from GAG to GUG • Glutamic Acid Changes to Valine • Hemoglobin protein behaves abnormally • Abnormal hemoglobin cause red blood cells to have a sickle shape. $300 Question 4.1 Basics Which of the following is the cause of sickle-cell anemia? A. Tryptophan is replaced by leucine. B. Leucine is replaced by valine. C. Glutamic acid is replaced by valine. D. Lysine is replaced by glutamic acid. $300 Answer 4.1 Basics Which of the following is the cause of sickle-cell anemia? C. Glutamic acid is replaced by valine. $400 Question 4.1 Basics 1) What is a genome? A) the complete complement of an organism's genes B) a specific sequence of polypeptides within each cell C) a specialized polymer of four different kinds of monomers D) a specific segment of DNA that is found within a prokaryotic chromosome E) an ordered display of chromosomes arranged from largest to smallest $400 Answer 4.1 Basics 1) What is a genome? A) the complete complement of an organism's genes $500 Question 4.1 Basics If the liver cells of an animal have 24 chromosomes, how many chromosomes do its sperm cells have? $500 Answer 4.1 Basics If the liver cells of an animal have 24 chromosomes, how many chromosomes do its sperm cells have? 12 chromosomes $100 Question 4.2 meiosis Match the key event of meiosis with the stages listed below. Tetrads of chromosomes are aligned at the center of the cell; independent assortment soon follows. a) b) c) d) e) f) g) h) prophase I prophase II metaphase I metaphase II anaphase I anaphase II telophase I telophase II $100 Answer from 4.2 meiosis Match the key event of meiosis with the stages listed below. Tetrads of chromosomes are aligned at the center of the cell; independent assortment soon follows. -- METAPHASE I $200 Question from 4.2 meiosis Match the key event of meiosis with the stages listed below. Centromeres of sister chromatids uncouple and chromatids separate. a) b) c) d) e) f) g) h) prophase I prophase II metaphase I metaphase II anaphase I anaphase II telophase I telophase II $200 Answer from 4.2 meiosis Match the key event of meiosis with the stages listed below. Centromeres of sister chromatids uncouple and chromatids separate. ANAPHASE II $300 Question from 4.2 meiosis Match the key event of meiosis with the stages listed below. Crossing over occurs during which phase of meiosis a) b) c) d) e) f) g) h) prophase I prophase II metaphase I metaphase II anaphase I anaphase II telophase I telophase II $300 Answer from 4.2 meiosis Match the key event of meiosis with the stages listed below. Crossing over occurs during which phase of meiosis PROPHASE I $400 Question from 4.2 meiosis Match the key event of meiosis with the stages listed below. Non-disjunction occurs at what phases of meiosis? a) b) c) d) e) f) g) h) prophase I prophase II metaphase I metaphase II anaphase I anaphase II telophase I telophase II $400 Answer from 4.2 meiosis Match the key event of meiosis with the stages listed below. Non-disjunction occurs at what phases of meiosis? – ANAPHASE I and II $500 Question from 4.2 meiosis What phase or phases below coul represent anaphase of MITOSIS? And explain how you know. $500 Answer from 4.2 meiosis Phase II and V, because sister chromosomes are being pulled apart. $100 Question 4.3 Monohybrid What type of inheritance is shown in this pedigree chart? A. B. C. D. X-linked dominant Y-linked dominant X-linked recessive Y-linked recessive $100 Answer from 4.3 Monohybrid What type of inheritance is shown in this pedigree chart? C. X-linked recessive $200 Question from 4.3 Monohybrid A man of blood group A and a woman of blood group B have a child. If both are heterozygous for the gene, what are the chances of them having a child with blood group B? $200 Answer from 4.3 Monohybrid A man of blood group A and a woman of blood group B have a child. If both are heterozygous for the gene, what are the chances of them having a child with blood group B? – 25 % $300 Question from 4.3 Monohybrid Which disease is an example of sexlinked (X-linked) inheritance? A. AIDS B. Down syndrome C. Sickle-cell anemia D. Hemophilia $300 Answer from 4.3 Monohybrid Which disease is an example of sexlinked (X-linked) inheritance? A. AIDS B. Down syndrome C. Sickle-cell anemia D. Hemophilia $400 Question 4.3 Monohybrid What evidence is given in the pedigree chart below to establish that the condition is caused by a dominant allele? $400 Answer from 4.3 Monohybrid Two affected parents have an unaffected child. $500 Question from 4.3 Monohybrid If an organism that is homozygous recessive for a trait is crossed with a heterozygote, what is the chance of getting a homozygous recessive phenotype in the first generation? $500 Answer from 4.3 Monohybrid If an organism that is homozygous recessive for a trait is crossed with a heterozygote, what is the chance of getting a homozygous recessive phenotype in the first generation? 50% $100 Question from 3.3 DNA / RNA /Protein Identify the name / letter of Z and Y $100 Answer 3.3 DNA / RNA /Protein Both are Nitrogenous Bases: Z = G = guanine Y= T= Thymine $200 Question 3.3 DNA/ RNA/ PROTEIN Which enzyme catalyzes the elongation of the leading strand? $200 Answer 3.3 DNA/ RNA/ Protein DNA Polymerase $300 Question DNA/ RNA/ Protein A certain gene in a bacterium codes for a polypeptide that is 120 amino acids long. How many nucleotides are needed in the mRNA to code for this polypeptide? $300 Answer DNA/ RNA/ Protein 360 nucleotides $400 Question DNA/ RNA/ Protein State the type of bonds that (i) connect base pairs in a DNA molecule. ................................................................................. (ii) link DNA nucleotides into a single strand. ....................................................................................... $400 Answer from DNA/ RNA/ PROTEINS State the type of bonds that (i) connect base pairs in a DNA molecule. HYDROGEN BONDS (ii) link DNA nucleotides into a single strand. COVALENT BONDS $500 Question 4.3 Monohybrid State three differences between RNA & DNA $500 Answer 4.3 Monohybrid DNA Double Stranded Deoxyribose sugar Thymine nitrogenous base RNA Single Stranded Ribose sugar Uracil Nitrogenous Base $100 Question 4.4 Biotechnology State the name of the technique that is used to separate fragments of DNA according to their size, during DNA profiling. $100 Answer 4.4 Biotechnology GEL ELECTROPHORESIS State the name of the technique that is used to separate fragments of DNA according to their size, during DNA profiling. $200 Question 4.4 Biotechnology Results of a paternity investigation. •Track A = mother of a child, •Track B = child • Track C = a man who might be the father. Explain, using evidence from the diagram, whether this man is the father or not. $200 Answer 4.4 Biotechnology NO ‘C’ is NOT the father or ‘B’ b/c B has DNA fragments that he did not inherit from his mom or the man represented by track C $300 QUESTION 4.4 Biotechnology Which process is used in polymerase chain reaction (PCR)? A. Transcription B. Translation C. Replication D. Mutation $300 Answer 4.4 Biotechnology Which process is used in polymerase chain reaction (PCR)? C. Replication Daily Double! $400 Question 4.4 Biotechnology Which enzymes are needed to incorporate genes into plasmids to create recombinant plasmids? $400 Answer 4.4 Biotechnology Which enzymes are needed to incorporate genes into plasmids to create recombinant plasmids? LIGASE and RESTRICTION ENZYMES $500 Question 4.4 Biotechnology A small amount of a suspect’s DNA is obtained from a crime scene. What techniques would be used to carry out DNA profiling? A. B. C. D. Gel electrophoresis and paternity testing Paternity testing and the polymerase chain reaction (PCR) Polymerase chain reaction (PCR) and gel electrophoresis Test crossing and pedigree analysis $500 Answer 4.4 Biotechnology A small amount of a suspect’s DNA is obtained from a crime scene. What techniques would be used to carry out DNA profiling? C. Polymerase chain reaction (PCR) and gel electrophoresis American Science fiction Old version (older than you) and new version (in the last five years) OLD BIBILICAL STORY –made into a movie(Older than Ms. Tyler) The story was recently remade into another movie, but with a different name. American Movie --Recently released Drama Based on a non-fiction best-selling novel American Drama Movie --Recently released American Movie Recently released Drama Nominated for many awards Boyhood American Movie Science fantasy Almost as Old as Ms. Tyler Many sequels/ prequels New one will be released soon. Star Wars– Episode 4 – The original