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MITOSIS FLIP BOOK ALEXIS TUCKER EARLY PROPHASE The nuclear membrane and the nucleolus start to disappear. The spindle fibers start to form. LATE PROPHASE The nucleus has completely disappeared. The spindle fibres have fully formed, and they attach themselves to the centromeres. METAPHASE The spindle fibres tug the X shaped chromosomes into a line across the middle of the cell. ANAPHASE The spindle fibres begin to contract and shorten which pulls the centromere apart to let the sister chromatids move to the opposite sides of the cell. Once they separate, each chromatid is a chromosome. TELOPHASE The spindle fibres begin to disappear, and a nuclear membrane forms around the chromosomes. A nucleolus appears within each nucleus. There are two nuclei in the cell, now it’s about to divide. CYTOKINESIS This is the final stage in mitosis. Cytokinesis separates the nuclei into two daughter cells which are identical to the original cell.