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What occurs during the M
phase?
Sections 8.6 and 8.7
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Mitosis and Cytokinesis
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Prophase (including prometaphase)

Nuclear membrane breaks
down

Chromatin condenses into
chromosomes

Spindle fibers appear

Centriole + spindle fibers =
centrosome

Centrosomes move to poles

Nucleolus disappears

Kinetochore of centromere on
each sister chromatid attaches to
spindle fiber
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Prophase…
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Metaphase

Spindle is fully formed

Chromosomes line up in the
“middle” of the cell (at the
metaphase plate – which is
between the poles of the cell)
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Anaphase

Nonkinetochore microtubules
elongate the cell

Centromeres of sister chromatids
split

Motor proteins of kinetochores pull
daughter chromosomes to the
poles centromere 1st along
microtubules

Ends when chromosomes reach
the poles
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Telophase

Nuclear membranes reappear
(one around each set of
chromosomes)

Chromosomes uncoil to
chromatin

Nucleolus reappears

Spindle breaks down

Cytokinesis begins during this
stage
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Cytokinesis

Division of cytoplasms

Starts during telophase

Animal Cells – pinching
inward forms a cleavage
furrow

Plant cells – vesicles align
between the two nuclei;
vesicles fuse to form a cell
plate; cell plate grows outward