Download Genetics Unit Syllabus 2016

GENETICS (GEN) – You can be a winner at the game of LIFE!
POWERSTANDARD/GENETICS
(CONTINUITY): Students will be able to convey an understanding (1) that continuity of a species is
dependent on the transfer of genetic information and that this transfer happens in a predictable fashion that leads to genetic expression, (2) of the
mechanism of cell division for somatic (mitosis) and sex cells (meiosis), and (3) of the structure and function of DNA & RNA to create proteins.
 GEN1, GENETIC STRUCTURE AND FUNCTION (mitosis, meiosis, DNA structure, replication)
O Use a model to demonstrate mitosis and meiosis (HS-LS1-4)
O Make and defend a claim based on evidence that inheritable genetic variation may result from (1) new genetic combinations during meiosis
(recombination and crossing over), (2) workable errors (mutations) occurring during replication, and/or (3) mutations caused due to
environmental factors. (HS-LS3-2)
 GEN2, GENES AND PROTEINS (transcription, translation)
O Construct an explanation for how DNA determines the structure of proteins. (HS-LS1-1)
 GEN3, GENETIC HEREDITY AND VARIATION (continuity, genetic variation, genotype, phenotype)
O Generate questions to understand the relationship between DNA and chromosomes in order to explain how genes code for specific
characteristics that are passed from parent to offspring (HS-LS3-1)
O Apply concepts of statistics and probability to explain variation and distribution of traits within a population. (HS-LS3-3)
TASK/EXAM: Demonstrate conceptual understanding of the areas of genetics in an essay or exam format with short and extended responses.
(CONTINUITY): Students will be able to
convey an understanding (1) that
continuity of a species is dependent on
the transfer of genetic information and
that this transfer happens in a predictable
fashion that leads to genetic expression,
(2) of the mechanism of cell division for
somatic (mitosis) and sex cells (meiosis),
and (3) of the structure and function of
DNA & RNA to create proteins.
POWERSTANDARD/GENETICS
RUBRIC: Demonstrate the following skills during an in-class exam…
4 – Exceeding
3 – Meeting
Complete all requirements for MEETING (3)
and…
includes some combination of the following:
o All questions are completely correct
o Some responses demonstrate greater
understanding than required for this class
(particularly in extended responses)
o Greater understanding demonstrated in the
evolutionary tree diagrams
All exam questions are correct though
answers may show minor errors that do not
affect conceptual understanding.
Demonstrate conceptual understanding of
the content listed below in the practice
questions.
2 – Approaching
1 – Beginning
Most exam questions are
correct but one or more answers
shows errors that demonstrate
misconceptions and/or lack of
understanding.
Most exam questions are
attempted but some to zero exam
questions are correct. One or
more answers show errors that
demonstrate misconceptions and/or
lack of understanding.
See content above
GENETICS UNIT SYLLABUS
day
Classwork & Homework
1 DAY
Genetic Pretesting
DNA, DNA Replication (synthesis), Mutation
SGI: GENETICS 10, Modeling DNA Structure (p.328-333) Analysis 1-3
If confused…REVIEW ASSIGNMENT: BSCS- Modeling DNA, Part A & B (p.456,
essay) DNA Structure & Replication (p.517-522)
SGI: GENETICS 12, DNA Replication (p.343-345) Analysis 1-2
If confused…REVIEW ASSIGNMENT: BSCS-(essay) DNA Structure & Replication
(p.517-522) and Replication Errors and Mutations (p.523-525)
THUR
FRI
Pick 1 VL from 1, 2, or 3 (watching more than one, watch each
only once & combine notes). Watch VL4 AND VL5.
VL1: What is DNA and how does it work? (Stated Clearly, 5:21)
VL2: DNA Structure (Teachers Pet, 4:21)
VL3: The structure of DNA (MITx BIO, 5:58)
VL4: DNA Replication: The Cell's Extreme Team Sport (Amoeba
Sisters, 7:58) SEPERATE NOTES REQUIRED
VL5: Mutations: The Potential Power of a Small Change (Amoeba
Sisters, 7:58) SEPERATE NOTES REQUIRED
MITOSIS AND MEIOSIS
SGI: GENETICS 13, Meiosis and Sexual Reproduction (p.346-352)
Analysis 1-4
If confused…REVIEW ASSIGNMENT: BSCS (essay) Meiosis: The Mechanism
behind Patterns of Inheritance (p.502-506)
VL: Mitosis: The Amazing Cell Process that Uses Division to Multiply! (Amoeba
Sisters,8:27)
VL: Meiosis: The Great Divide (Amoeba Sisters, 7:41)
Watch the two music videos...no notes required
 Mitosis Rap: Mr. W’s Cell Division Song
 Meiosis! (Mr. W’s Music Video)
VL: Chromosome Numbers During Division: Demystified? (Amoeba
Sisters, 5:46)
HW: SGI: GENETICS14, Genes and Chromosomes (p.353-360)
reading, 2-column notes, Analysis1-5
CONTENT
STANDARD
DNA structure (consistent width),
nucleotide, nitrogen base, base pair,
hydrogen bonds, double helix
(single helix), DNA replication,
enzymes
GEN1, GENETIC
STRUCTURE AND
FUNCTION
DNA replication, DNA structure
nucleotide, single helix, enzymes
GEN1, GENETIC
STRUCTURE AND
FUNCTION
GEN3, GENETIC HEREDITY
AND VARIATION
Meiosis, crossing over, mitosis,
gamete, daughter cell, Genetically
Modified Organism (GMO)
GEN1, GENETIC
STRUCTURE AND
FUNCTION
diploid, haploid, nondisjunction
(monosomy VS trisomy), law of
independent assortment
GEN1, GENETIC
STRUCTURE AND
FUNCTION
Complete
SGI: GENETICS 8, Interpreting Pedigrees (p.300) Part A, Part B,
Analysis 1-6
MON
If confused…REVIEW ASSIGNMENTS: BSCS- Gifts from your parents (p.422) and
(essay) Case Studies of Two Genetic Disorders (p.500-502)
VL: What are Pedigree Charts (Mark Drollinger, 4:23)
VL: Pedigree Analysis in Human Genetics, http://study.com/academy/lesson/pedigreeanalysis-in-human-genetics-tutorial.html
VL: Solving Pedigree Genetics Problems (BiologyMonk, 12:25)
VL: What is a gene? (Stated Clearly, 4:56)
AFTER
SCHOOL
TUES
Pedigree, inheritance, dominant,
recessive
GEN3, GENETIC HEREDITY
AND VARIATION
See above
GEN3, GENETIC HEREDITY
AND VARIATION
transcription, mRNA (messenger
Ribonucleic Acid), tRNA (transfer
Ribonucleic Acid), enzymes,
nucleotides C/G/A/U (Uracil),
translation, amino acid, protein
synthesis, protein
GEN2, GENES AND
PROTEINS
See above
GEN2, GENES AND
PROTEINS
Boot Camp…focus on ecology and evolution
VL: Crash Course Biology: Ecosystem Ecology: Links in the Chain
5 fingers of evolution
SGI: GENETICS 16, Protein Synthesis & Mutations, Part A
If confused…REVIEW ASSIGNMENT: BSCS- A Closer Look at Protein Synthesis
(p.468) (essay) The Expression of Genetic Information (p.525-528) and Translating
the Message in the mRNA (p.528-531) and Cellular Components in Protein
Synthesis (p.531-534)
SGI: GENETICS 17, Cell Differentiation & Gene Expression (p.376)
VL: Protein Synthesis and the Lean, Mean Ribosome Machines
(Amoeba Sisters, 7:07)
VL: Transcription and Translation (Bozeman, 11:56)
Boot Camp…cellular energy (EMO), homeostasis, cell bio
AFTER
SCHOOL
WED
VL: Crash Course Biology, Photosynthesis
VL: Crash Course Biology, ATP & Cellular Respiration
VL: Crash Course Biology, In Da Club-Membranes & Transport
SGI: GENETICS 17, Cell Differentiation and Gene Expression
(p.376-384) Analysis 1, 2, 3, 4, 5, 6, 7)
Determining Genetic Probability with Punnett Squares
If confused…REVIEW ASSIGNMENT: A Beginner's Guide to Punnett Squares
(Bozeman, 12:15)
VL: Gene Regulation (Bozeman, 10:05)
VL: How Mendel's pea plants helped us understand genetics - Hortensia
Jiménez Díaz (3:06)
VL: Monohybrids and the Punnett Square Guinea Pigs (Amoeba Sisters, 6:27)
VL: Epigenetics (Bozeman, 9:20)
AFTER
SCHOOL
ESSAY ASSESSMENT
THUR
WED
THUR
Chromosome, gene expression,
repression, transcription factors
GEN2, GENES AND
PROTEINS
GEN3, GENETIC HEREDITY
AND VARIATION
Punnett Square, genetic probability,
monohybrid, dihybrid, allele,
dominant, recessive, co-dominance,
incomplete dominance Epigenetics,
environment
GEN2, GENES AND
PROTEINS
GEN3, GENETIC HEREDITY
AND VARIATION
Boot Camp…genetics
VL: Heredity: Crash Course Biology #9 (10:17)
End of Course BIOLOGY EXAM
STANDARD Assessment Task (5-paragraph essay): How do the characteristics from one generation relate to the
previous generation while still promoting genetic variation? – GEN3, GENETIC HEREDITY AND VARIATION
TASK/ESSAY: Demonstrate conceptual understanding of the relationship between DNA and chromosomes, sources of genetic variation and how to determine the
probability of a specific gene outcome to inlcude mitosis, meiosis, DNA, DNA replication transcription, translation, and protein expression. This would include a working
knowledge of the following concepts and terms: mitosis, parent & daughter cells, meiosis, homologous, genetic recombination, linked genes, crossing over, diploid (2N),
haploid (1N), and polyploidy (4N), gamete, DNA (deoxyribonucleic acid), nucleotide, nitrogenous base A (Adenine) T (thymine) C (Cytosine) G (guanine), base pair,
hydrogen bond, single & double helix, replication, enzymes, mutation (point mutation, frame shift, deletion, addition, substitution), SNP, transcription, mRNA (messenger
Ribonucleic Acid), tRNA (transfer Ribonucleic Acid), enzymes, nucleotides C/G/A/U (Uracil), translation, amino acid, protein, protein synthesis, genotype, phenotype,
gene expression, environmental factors, allele, gamete, Punnett Square, genetic probability, offspring, heritable characteristics, dominance, recessive, co-dominance,
incomplete dominance, homozygous, heterozygous.
GEN1, GENETIC MECHANISM (mitosis, meiosis, DNA structure, replication)
EXAM(s)
TASK/EXAM: Demonstrate conceptual understanding of mitosis, meiosis, DNA, and DNA replication in an exam format that includes short and extended responses.
This would include a working knowledge of the following concepts and terms: mitosis, parent & daughter cells, meiosis, homologous, genetic recombination, linked
genes, crossing over, diploid (2N), haploid (1N), and polyploidy (4N), gamete, DNA (deoxyribonucleic acid), nucleotide, nitrogenous base A (Adenine) T (thymine) C
(Cytosine) G (guanine), base pair, hydrogen bond, single & double helix, replication, enzymes, mutation (point mutation, frame shift, deletion, addition, substitution), SNP
GEN2, GENES & PROTEINS (transcription, translation)
TASK/EXAM: Demonstrate conceptual understanding of transcription, translation, and protein expression in an exam format that includes short and extended
responses. This would include a working knowledge of the following concepts and terms: transcription, mRNA (messenger Ribonucleic Acid), tRNA (transfer Ribonucleic
Acid), enzymes, nucleotides C/G/A/U (Uracil), translation, amino acid, protein, protein synthesis
GEN3, GENETIC HEREDITY AND VARIATION (continuity, genetic variation, genotype, phenotype)
TASK/EXAM: Demonstrate conceptual understanding of the relationship between DNA and chromosomes, sources of genetic variation and how to determine the
probability of a specific gene outcome in an exam format that includes short and extended responses. This would include a working knowledge of the following concepts
and terms: genotype, phenotype, gene expression, environmental factors, allele, mutation, SNP, gamete, Punnett Square, genetic probability, offspring, heritable
characteristics, dominance, recessive, co-dominance, incomplete dominance, homozygous, heterozygous
Practice Questions
1. Draw and label the components of a single nucleotide.
2. Explain the connection/relationship between DNA and chromosomes.
3. Regular/somatic human cells, have ______(#) chromosomes or _______(#) pairs. Gametes/sex cells have
______(#) chromosomes or _______(#) pairs.
4. Write the complimentary side of the DNA helix represented below.
TAA GTC TAC ACC GTG GGC GTA AGT CAG GTC AGC ACC ATC CTA
5. Which letters demonstrate linkage in Figure 1. Chromosomes with Gene Bands
6. Meiosis is a type of cell division that results in the production of…
Figure 1.
Chromosomes
with Gene
Bands
7. Complimentary base pair share a specific number of Hydrogen bonds. Explain the
importance of having a different number of hydrogen bonds connecting complimentary base
pair.
GENOMES
1N – 1 genome (one complete set of genes/chromosomes)
2N – 2 genomes (2 complete set of genes/chromosomes)
4N – 4 genomes (4 complete set of genes/chromosomes)
8. Draw and identify the number of genomes (N) in each of the Mitosis phases.
9. Draw and identify the number of genomes (N) in each of the Meiotic phases.
10. What are the 4 nitrogen bases in DNA (by name):
11. Explain how the shape, size, & compliment of the nitrogen bases in the nucleotide help promote stability in DNA.
Include a diagram if it adds to your explanation.
12. What are the mutations types? How does replication lead to mutations?
13. Mark the mutation location. What kind of mutation is occurring here? _______________________
Original DNA: TAA ATC TAC AGT GTG GGC GGT AGT GAG GAC ATC CTA
Mutated DNA: TAA ATC TAC AGT GTG GGC GTA GTG AGG ACA TCC TAG
GEN2, GENES AND PROTEINS (transcription, translation)
 Construct an explanation for how DNA determines the structure of proteins. (HS-LS1-1)
GEN3, GENETIC HEREDITY AND VARIATION (continuity, genetic variation, genotype, phenotype)
 Generate questions to understand the relationship between DNA and chromosomes in order to explain how genes code for specific
characteristics that are passed from parent to offspring (HS-LS3-1)
 Apply concepts of statistics and probability to explain variation and distribution of traits within a population. (HS-LS3-3)
1. Which letters demonstrate linkage in Figure 1. Chromosomes with Gene Bands.
For each of the following traits in Figure 1, does this individual present as homozygous or
heterozygous? For Dimples? For Brow Shape?
Figure 1.
Chromosomes
with Gene
Bands
Repeat
UNIT SYLLABUS
Approximate #
of days
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Classwork & Homework Assignments
-Cracking the Code of Life, video on DNA, the
human genome, genetic therapy, and bioethics
-Cracking the Code of Life continued
Ug’Le Bebe…babies enter the nursery
-Genetic Testing for Huntington’s Disease, Part 2
-SGI: GENETICS 4, Breeding Corn (p.282)
worksheet (Punnett Squares)
ALTERNATE ASSIGNMENT & REVIEW: BSCSModeling DNA, Part A & B (p.456)
Ug’Le Bebe Competition
-SGI: GENETICS 4, Breeding Corn (p.282)
continued… Analysis 1-3
ALTERNATE ASSIGNMENT & REVIEW: BSCSPatterns of Inheritance (p.431) and (essay)
Phenotype & Genotype (p.496-499)
HOMEWORK: SGI: GENETICS 5, Genes and
Traits (p.290) read with Stop and Think protocol
-SGI: GENETICS 5, Genes and Traits (p.290)
discussion & Analysis 1, 2, & 4
-Mendel video clips
ALTERNATE ASSIGNMENT & REVIEW: BSCSCan You Sort It Out? (p.438)
HOMEWORK: finish for homework
-SGI: GENETICS 6, Breeding Corn for Two Traits
(p.300) continued… Analysis 1 & 2
HOMEWORK: SGI: GENETICS 6, Breeding Corn
for Two Traits (p.306) complete Analysis 1 & 2
-SGI: GENETICS 8, Interpreting Pedigrees (p.300)
Part A
ALTERNATE ASSIGNMENT & REVIEW: BSCSGifts from your parents (p.422) and (essay) Case
Studies of Two Genetic Disorders (p.500-502)
HOMEWORK: SGI: GENETICS 8, Interpreting
Pedigrees (p.300) Part A
-SGI: GENETICS 8, Interpreting Pedigrees (p.300)
Part A, Part B, Analysis 1-6
ALTERNATE ASSIGNMENT & REVIEW: BSCSGifts from your parents (p.422) and (essay) Case
Studies of Two Genetic Disorders (p.500-502)
HOMEWORK: SGI: GENETICS 8, Interpreting
Pedigrees (p.300) finish for home work
-Genetic Testing for Huntington’s Disease, Part 3
REVIEW
STANDARD GEN1 EXAM
-Genetic Testing for Huntington’s Disease, Part 4
-SGI: CELL BIOLOGY 13, The Cell Cycle (p.229)
The Cell Cycle Game, complete Analysis 1-6
ALTERNATE ASSIGNMENT & REVIEW: BSCS
(essay)- The Cell Cycle and Growth Control
(p.582-584)
HOMEWORK: Finish CELL BIOLOGY 13 for
homework.
CONTENT
STANDARD
Completed
Day
Day
Day
Day
-SGI: CELL BIOLOGY 13, The Cell Cycle (p.229)
The Cell Cycle Game, complete Analysis 1-6
ALTERNATE ASSIGNMENT & REVIEW: BSCS
(essay)- The Cell Cycle and Growth Control
(p.582-584)
HOMEWORK: Finish CELL BIOLOGY 13 for
homework.
-SGI: GENETICS 14, Genes and Chromosomes
(p.353)
ALTERNATE ASSIGNMENT & REVIEW: BSCSModeling DNA (p.456)
STANDARD
-SGI: GENETICS 16, Protein Synthesis &
Mutations
ALTERNATE ASSIGNMENT & REVIEW: BSCS- A
Closer Look at Protein Synthesis (p.468) (essay)
The Expression of Genetic Information (p.525528) and Translating the Message in the mRNA
(p.5298-531) and Cellular Components in Protein
Synthesis (p.531-534)
SGI: GENETICS 17, Cell Differentiation & Gene
Expression (p.376)
Genetic Testing for Huntington’s Disease, Part 5
ALTERNATE ASSIGNMENT & REVIEW: BSCSGene Expression (p.462)