* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Handbook of Protein Sequences: A Compilation of Amino Acid
Nucleic acid analogue wikipedia , lookup
Magnesium transporter wikipedia , lookup
Protein (nutrient) wikipedia , lookup
SNARE (protein) wikipedia , lookup
Ancestral sequence reconstruction wikipedia , lookup
G protein–coupled receptor wikipedia , lookup
Ribosomally synthesized and post-translationally modified peptides wikipedia , lookup
Protein moonlighting wikipedia , lookup
Protein domain wikipedia , lookup
Circular dichroism wikipedia , lookup
Expanded genetic code wikipedia , lookup
Cell-penetrating peptide wikipedia , lookup
Endomembrane system wikipedia , lookup
Protein adsorption wikipedia , lookup
Size-exclusion chromatography wikipedia , lookup
Genetic code wikipedia , lookup
Protein–protein interaction wikipedia , lookup
List of types of proteins wikipedia , lookup
Protein structure prediction wikipedia , lookup
Western blot wikipedia , lookup
Amino acid synthesis wikipedia , lookup
BOOK REVIEWS 353 Preparative ‘Techniques.All three are edited by Eric Reid, and are based on symposia at the University of Surrey. The symposium that gave rise to Volume 3 was held in December 1971. During the last few years zonal centrifuges have become more widely and more routinely used in biochemical separations, and many improvements have appeared in apparatus and technique. As the title suggests Volume 3 is to some extent an up-dated version of Volume I-there are a dozen authors in common. Of the 30 articles, 20 describe separations of a wide variety of biological particles: proteins, nucleic acids, ribosomes, viruses, lysosomes and membrane fragments, whole brain cells, and fish eggs and larvae. These articles are mostly short. Though not designed to be a comprehensive handbook of zonal centrifugation, Volume 3 gives a good idea of the broad range of zonal centrifugation techniques, particularly if taken with Volume 1. It also contains a number of articles intended to guide the novice around the many pitfalls in experimental design, with sections on the basic theory of zonal centrifugation, apparatus, and even a note on the training of staff. It is unfortunate that a ‘state of the art’ book such as this should have taken so long to produce. It appears at almost the same time as another zonal symposium book (Spectra, No. 4, 1973, Editions Cit6 Nouvelle, Paris), which has taken only 12months. Many biochemists will feel, however, that there is enough useful material here to justify spending E3.00. DAVID RIDGE Handbook of Protein Sequences: A Compilation of Amino Acid Sequences of Proteins L. R. CROFT (Editor) Joyson-Bruvvers, Oxford, 1973, pp. 172, €5.50 (library binding), €2.95 (looseleafl The Handbook produced by Dr. Croft is a testimony to his industry and patience. It should find a place in a11 biochemistry departments. While appreciative of the difficulties involved and bearing in mind the intention to supply annual updates, one must comment that the lay-out might have been improved if proteins had been presented in phylogenic sequence. The cytochromes, for example, demonstrate ‘phylogenic changes’ very clearly but Neurospora crassa cytochrome is sandwiched between those of the dogfish and the snapping turtle. The transparent sheet provided for the location of residues (which are in lines of 17 units) is not without its drawbacks: for instance, aspartate aminotransferase (p. 26) has 412 and bovine glutamate dehydrogenase(p. 4) has 500 residues whereas the acetate sheet stops short at 340. If the Handbook is reproduced in toto it might be advantageous to have 20 residues per line and to number the vertical lines in units not only to produce a grid reference but also to facilitate the location of individual residues. It might also be useful to provide the coding data for the incorporation of amino acids into proteins so that students and others can study the implications of genetic differences. Dr. Croft is to becongratulated on hisefforts: the Handbookis cheap at the price! One spelling mistake appears in the Index, where kangaroo (kangeroo) is misspelt on each occasion. G. R. TRISTRAM ~ The Enzymes of Glutamine Metabolism STANLEY PRUSINER and EARL R. STADTMAN (Editors) Academic Press, New York, 1973, pp. 615, f7.35 This collection of papers on all aspects of glutamine metabolism follows a symposium held at the 164th National Meeting of the American Chemical Society. VOl. 2