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Subject Description Form Subject Code ABCT203 Subject Title Cell Biology Credit Value 3 credits Level 2 Pre-requisite / Co-requisite/ Exclusion None Objectives To develop students an understanding of basic chemical components of cells; an appreciation of the structures and functions of cell organelles and the cell as an entity. Intended Learning Outcomes On successfully completing this subject, students will be able to Subject Synopsis/ Indicative Syllabus 1. describe the structural organization of prokaryotic and eukaryotic cells, including an introduction to the major types of organelles, their functions and the relationship between organelle architecture and functions. 2. relate the properties and functions of plasma membrane to its structural architecture. 3. explain the phenomena that are essential to the activities of all living cells: energy transformations and the use of enzymes to catalyze chemical reactions. 4. integrate the working principles of different microscopies commonly used in cell biology and be able to apply the techniques in different situations. 5. identify the sequence and different signaling molecules involved in controlling a eukaryotic cell cycle. 6. explain the nature of stem cell and recognize its potential applications. Introduction to Cells Prokaryotic and eukaryotic cells, microscopy Chemistry of Cells Importance of water; biomolecules in cells, bioenergetics and catalysis Structure and Function of Cell Organelles The architecture of plasma membrane, transport across membrane, internal membranes and cell energetic; chemical signaling between cells; cytoskeleton and cell movement; endoplasmic reticulum, ribosomes, Golgi apparatus, lyzosomes, peroxisomes, mitochondrion, chloroplast and the nucleus. Cell Cycles and Development of Cell Specificity in Eukaryotes Cell cycle and cells in early stage of development; control of cell growth and cell signaling; cell lineage and differentiation. 1.2011 Teaching/Learning Methodology Lectures are provided for students to acquire general and basic understandings and concepts of the subject. By an interactive approach, students are encouraged to raise questions and answer the questions in class after the lecture period. Tutorials are designed to provide the environment for discussions on the subject materials. In-depth exercises and case studies are held in the tutorials helping students develop relational study among different areas of the subject. Practical classes allow students to experience some major and essential experimental techniques and to train them to develop their ability of designing experiments, data interpretation and report writing. The practical works also help students put their knowledge into practice. The continuous assessment consists of different components: group presentations, laboratory report write-ups and quizzes. The content of each component is in line with the content of the interactive lectures taught in class. Examination is focused on analytical skills and problem solving skills in solving problems in cell biology. Assessment Methods in Alignment with Intended Learning Outcomes Specific assessment methods/tasks % weighting Intended subject learning outcomes to be assessed (Please tick as appropriate) 1 2 3 4 5 1. Quiz 1 20 2. Quiz 2 20 3. Lab. Report 5 4. Tutorial 5 5. Exam 50 Total 100 % Explanation of the appropriateness of the assessment methods in assessing the intended learning outcomes: Students are required to pass both examination and continuous assessment for the completion of the subject. Student Study Effort Required Class contact: lecture and tutorial lab 38Hrs. 6Hrs. Other student study effort: 1.2011 self-study 42Hrs. Total student study effort Reading List and References The World of the Cell (6th Ed) – Becker W.M., Kleinsmith, L.J. & Hardin, J. 2005 Int. Ed. Essential Cell Biology (2nd Ed) – Alberts, B. et al. – Garland 2003 1.2011 Hrs. 42Hrs. Pearson/Benjamin/Cummings