Vitreous Anatomy and Pathology
... and chemical composition of these structures may account for, among other phenomena, the frequency with which abnormal cell proliferation arises from or near the optic disc in proliferative diabetic retinopathy and premacular membranes with macular pucker. The vitreous is known to be most firmly att ...
... and chemical composition of these structures may account for, among other phenomena, the frequency with which abnormal cell proliferation arises from or near the optic disc in proliferative diabetic retinopathy and premacular membranes with macular pucker. The vitreous is known to be most firmly att ...
Reducing Ryanodine Receptor Open Probability as a Means to
... Systolic Ca2ⴙ Efflux After Tetracaine Application The above analysis demonstrates that cells can balance Ca2⫹ fluxes without recourse to waves of Ca2⫹ release caused by an increase of the amount of Ca2⫹ efflux that occurs during the systolic Ca2⫹ transient. This increased Ca2⫹ efflux could be mediat ...
... Systolic Ca2ⴙ Efflux After Tetracaine Application The above analysis demonstrates that cells can balance Ca2⫹ fluxes without recourse to waves of Ca2⫹ release caused by an increase of the amount of Ca2⫹ efflux that occurs during the systolic Ca2⫹ transient. This increased Ca2⫹ efflux could be mediat ...
Auxin: The Growth Hormone - Roberto Cezar | Fisiologista Vegetal
... amounts to its site of action qualified it as an authentic plant hormone. In the years that followed, the chemical identity of the “growth substance” was determined, and because of its potential agricultural uses, many related chemical analogs were tested. This testing led to generalizations about t ...
... amounts to its site of action qualified it as an authentic plant hormone. In the years that followed, the chemical identity of the “growth substance” was determined, and because of its potential agricultural uses, many related chemical analogs were tested. This testing led to generalizations about t ...
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... vertebrate skeletal development. The multi-step process of endochondral bone formation begins with the condensation of mesenchymal progenitor cells. These condensed mesenchymal cells then differentiate into chondrocytes to form the cartilage anlagen. In the developing long bones, chondrocytes underg ...
... vertebrate skeletal development. The multi-step process of endochondral bone formation begins with the condensation of mesenchymal progenitor cells. These condensed mesenchymal cells then differentiate into chondrocytes to form the cartilage anlagen. In the developing long bones, chondrocytes underg ...
Rehabilitating a Foal After Trauma
... q24h) and potassium penicillin (22,000 IU/kg IV q6h). Antiinflammatory treatments included flunixin meglumine (1.1 mg/kg IV q12h) and dimethyl sulfoxide (DMSO; 0.4 g/kg in 1 L lactated Ringer solution [LRS] IV q12h). Free radicals may be released from damaged central nervous system tissue and subseq ...
... q24h) and potassium penicillin (22,000 IU/kg IV q6h). Antiinflammatory treatments included flunixin meglumine (1.1 mg/kg IV q12h) and dimethyl sulfoxide (DMSO; 0.4 g/kg in 1 L lactated Ringer solution [LRS] IV q12h). Free radicals may be released from damaged central nervous system tissue and subseq ...
Auxin transport routes in plant development
... The plant hormone auxin (the predominant form of which is indole3-acetic acid; IAA) is a major coordinating signal in the regulation of plant development. Many aspects of auxin action depend on its differential distribution within plant tissues, where it forms local maxima or gradients between cells ...
... The plant hormone auxin (the predominant form of which is indole3-acetic acid; IAA) is a major coordinating signal in the regulation of plant development. Many aspects of auxin action depend on its differential distribution within plant tissues, where it forms local maxima or gradients between cells ...
PDF - Blood Journal
... from ER to cytoplasm has been demonstrated to limit the length of time proteins remain in the ER.11,12 To assess whether the calnexin cycle or proteasomal degradation contributes to ␣IIb3 biogenesis, we have performed pulse-chase and steady-state analyses in cells transfected with 3 in combination ...
... from ER to cytoplasm has been demonstrated to limit the length of time proteins remain in the ER.11,12 To assess whether the calnexin cycle or proteasomal degradation contributes to ␣IIb3 biogenesis, we have performed pulse-chase and steady-state analyses in cells transfected with 3 in combination ...
Potentiation of acid-sensing ion channels by sulfhydryl compounds
... glucose, penicillin-streptomycin, and insulin-selenite-transferrin) and triturated. Hippocampal cells (5 ⫻ 105 cells/well) were plated onto collagen-coated 10-mm coverslips in 24-well culture dishes. After 72 h, cytosine -D-arabinofuranoside was added to inhibit glial proliferation. After 10 days i ...
... glucose, penicillin-streptomycin, and insulin-selenite-transferrin) and triturated. Hippocampal cells (5 ⫻ 105 cells/well) were plated onto collagen-coated 10-mm coverslips in 24-well culture dishes. After 72 h, cytosine -D-arabinofuranoside was added to inhibit glial proliferation. After 10 days i ...
“Bio-X has been my guide and resource to leading world experts
... based on optical coherence tomography, nanoparticles, and novel reconstruction algorithms that together will allow molecular characterization of every cell in real-time. As an example, this technology can be used to study tumor heterogeneity and drug resistance of cancer. ...
... based on optical coherence tomography, nanoparticles, and novel reconstruction algorithms that together will allow molecular characterization of every cell in real-time. As an example, this technology can be used to study tumor heterogeneity and drug resistance of cancer. ...
C/EBPα triggers proteasome‐dependent degradation of cdk4 during
... (Wang et al., 2001). A detailed analysis of cdk4 in livers of wild-type and C/EBPa-knockout animals indicated a complex regulation of cdk4 by C/EBPa. In addition to the direct inhibition of cdk4 activity, C/EBPa also controls protein levels of cdk4. Figure 1A shows western blotting analysis of cdk4 ...
... (Wang et al., 2001). A detailed analysis of cdk4 in livers of wild-type and C/EBPa-knockout animals indicated a complex regulation of cdk4 by C/EBPa. In addition to the direct inhibition of cdk4 activity, C/EBPa also controls protein levels of cdk4. Figure 1A shows western blotting analysis of cdk4 ...
Modelling and treating dysregulated fibrosis in primary open angle
... induced by reduced outflow of aqueous humour through the trabecular meshwork due to fibrosis, which causes retinal ganglion cell death and loss of vision. This study aimed to: 1), create a rodent model of increased intraocular pressure achieved by the induction of trabecular meshwork fibrosis; 2), e ...
... induced by reduced outflow of aqueous humour through the trabecular meshwork due to fibrosis, which causes retinal ganglion cell death and loss of vision. This study aimed to: 1), create a rodent model of increased intraocular pressure achieved by the induction of trabecular meshwork fibrosis; 2), e ...
Redefining the role of ectoderm in somitogenesis
... Fgf signalling (Diez del Corral et al., 2003) and somite anteriorposterior polarity is established (Saga and Takeda, 2001). Furthermore, the first signs of morphological somite formation occur as peripheral PSM cells undergo a mesenchymal-to-epithelial transition (Duband et al., 1987; Kulesa and Fra ...
... Fgf signalling (Diez del Corral et al., 2003) and somite anteriorposterior polarity is established (Saga and Takeda, 2001). Furthermore, the first signs of morphological somite formation occur as peripheral PSM cells undergo a mesenchymal-to-epithelial transition (Duband et al., 1987; Kulesa and Fra ...
Vitreous and Developmental Vitreoretinopathies
... In the child, it is virtually impossible to mechanically detach the posterior cortical vitreous from the retina, resulting in surgical complications such as retinal breaks. The interface between vitreous and retina consists of a complex formed by the posterior vitreous cortex and the internal limiti ...
... In the child, it is virtually impossible to mechanically detach the posterior cortical vitreous from the retina, resulting in surgical complications such as retinal breaks. The interface between vitreous and retina consists of a complex formed by the posterior vitreous cortex and the internal limiti ...
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... regarding the physiological and genomic characterization of N. mobilis is still lacking because of the limited success in isolating it into pure cultures. Recently, the pure culture of Nitrosomonas mobilis Ms1 has been successfully isolated from the autotrophic nitrifying granules by selective isola ...
... regarding the physiological and genomic characterization of N. mobilis is still lacking because of the limited success in isolating it into pure cultures. Recently, the pure culture of Nitrosomonas mobilis Ms1 has been successfully isolated from the autotrophic nitrifying granules by selective isola ...
Lipoprotein Lipase in the Arterial Wall
... intima is derived from local synthesis, notably by the monocyte-derived macrophages.26,32–35 Most interestingly, immunohistochemical staining for LPL in the arterial intima has shown that LPL is not only associated with intimal cells but is also abundantly present within the extracellular matrix.31, ...
... intima is derived from local synthesis, notably by the monocyte-derived macrophages.26,32–35 Most interestingly, immunohistochemical staining for LPL in the arterial intima has shown that LPL is not only associated with intimal cells but is also abundantly present within the extracellular matrix.31, ...
Slow Ventricular Conduction in Mice Heterozygous for a
... of each tissue (1, 5, 7). Thus, tissue-specific connexin phenotypes and gap junction distributions appear to be major determinants of the disparate conduction properties of cardiac tissues. Although this hypothesis is supported by a large body of indirect evidence, there has been no direct analysis ...
... of each tissue (1, 5, 7). Thus, tissue-specific connexin phenotypes and gap junction distributions appear to be major determinants of the disparate conduction properties of cardiac tissues. Although this hypothesis is supported by a large body of indirect evidence, there has been no direct analysis ...
Wound Care: Part II Jassin M. Jouria, MD Dr. Jassin M. Jouria is a
... who opt to specialize in wound care provide an important skillset to patients suffering from chronic or acute injury, disease, or medical treatment. Most of these nurses adopt a holistic approach, coordinating efforts from the medical team to ensure that all aspects of a patient's health are conside ...
... who opt to specialize in wound care provide an important skillset to patients suffering from chronic or acute injury, disease, or medical treatment. Most of these nurses adopt a holistic approach, coordinating efforts from the medical team to ensure that all aspects of a patient's health are conside ...
Human Eosinophils from Transport-Mediated Release of Preformed
... on microscopic observations of individual viable cells, was performed as detailed (18) to enumerate the proportion of eosinophils releasing IL-4 and to electronically quantitate the average relative amounts of IL-4 released extracellularly. A biotinylated goat polyclonal anti-IL-4 Ab (20 g/ml; R&D ...
... on microscopic observations of individual viable cells, was performed as detailed (18) to enumerate the proportion of eosinophils releasing IL-4 and to electronically quantitate the average relative amounts of IL-4 released extracellularly. A biotinylated goat polyclonal anti-IL-4 Ab (20 g/ml; R&D ...
Receptor-regulated Dynamic S-Nitrosylation of Endothelial Nitric
... Alexa Fluor 568 anti-rabbit IgG secondary antibody was from Molecular Probes (Eugene, OR). SuperSignal substrate for chemiluminescence detection, Immunopure IgG elution buffer, biotin-HPDP, and horseradish peroxidase conjugated to secondary antibodies and to avidin (avidinHRP) were from Pierce. PCR ...
... Alexa Fluor 568 anti-rabbit IgG secondary antibody was from Molecular Probes (Eugene, OR). SuperSignal substrate for chemiluminescence detection, Immunopure IgG elution buffer, biotin-HPDP, and horseradish peroxidase conjugated to secondary antibodies and to avidin (avidinHRP) were from Pierce. PCR ...
Receptor-like activity evoked by extracellular ADP in Arabidopsis
... be equally or more effective than extracellular ATP (Demidchik et al., 2003a, 2009; Jeter et al., 2004; Tanaka et al., 2010b). In common with extracellular ATP, extracellular ADP can elicit oscillations of [Ca2+]cyt in Arabidopsis seedlings (Tanaka et al., 2010b). At the physiological level, extrac ...
... be equally or more effective than extracellular ATP (Demidchik et al., 2003a, 2009; Jeter et al., 2004; Tanaka et al., 2010b). In common with extracellular ATP, extracellular ADP can elicit oscillations of [Ca2+]cyt in Arabidopsis seedlings (Tanaka et al., 2010b). At the physiological level, extrac ...
VEGFR2 but not VEGFR3 governs integrity and remodeling of
... glands, each thyroid follicle is surrounded by a rich capillary network which provides substrates for hormone synthesis and transports the released hormones (Colin et al, 2013). The thyroid capillaries have a distinguishable characteristic of endothelial fenestrae, transcellular pores that are 60–80 ...
... glands, each thyroid follicle is surrounded by a rich capillary network which provides substrates for hormone synthesis and transports the released hormones (Colin et al, 2013). The thyroid capillaries have a distinguishable characteristic of endothelial fenestrae, transcellular pores that are 60–80 ...
375 Na+/Ca2+ ANTIPORT IN THE MAMMALIAN HEART
... Na+/Ca2+ antiporter and the Na+/K+-ATPase appear to be closely associated with each other and with the sarcoplasmic reticulum (Moore et al. 1993). In ventricular myocytes, the antiporter appears to be localized primarily to the T-tubules (Frank et al. 1992), although a second report disputes this cl ...
... Na+/Ca2+ antiporter and the Na+/K+-ATPase appear to be closely associated with each other and with the sarcoplasmic reticulum (Moore et al. 1993). In ventricular myocytes, the antiporter appears to be localized primarily to the T-tubules (Frank et al. 1992), although a second report disputes this cl ...
Spatial and temporal in vivo analysis of circulating
... of its effect on transmission dynamics, the mosquito immune response could be harnessed for the control of mosquito-borne diseases [11-13]. In both the culicine and anopheline mosquito lineages there are several morphologically distinct classes of hemocytes: granulocytes are involved in the phagocyt ...
... of its effect on transmission dynamics, the mosquito immune response could be harnessed for the control of mosquito-borne diseases [11-13]. In both the culicine and anopheline mosquito lineages there are several morphologically distinct classes of hemocytes: granulocytes are involved in the phagocyt ...
Regional requirements for Dishevelled signaling during Xenopus
... (http://bij.isi.uu.nl/flowj.htm) (Abramoff et al., 2000) for ImageJ (http://rsb.info.nih.gov/ij/). The resulting flow fields for selected frames within the time-lapse movies were visualized using DC format spot noise also implemented by the FlowJ plugin. In these images color is used to code the dir ...
... (http://bij.isi.uu.nl/flowj.htm) (Abramoff et al., 2000) for ImageJ (http://rsb.info.nih.gov/ij/). The resulting flow fields for selected frames within the time-lapse movies were visualized using DC format spot noise also implemented by the FlowJ plugin. In these images color is used to code the dir ...
Arabidopsis VILLIN4 is involved in root hair growth through
... regulator of actin filament stability in pollen (Zhang et al., 2010). As both AtVLN3 and AtVLN5 can sever actin filaments at physiological Ca2+ concentrations in vitro, they have been proposed to be involved in regulating actin filament turnover in response to alteration of Ca2+ levels in plant cell ...
... regulator of actin filament stability in pollen (Zhang et al., 2010). As both AtVLN3 and AtVLN5 can sever actin filaments at physiological Ca2+ concentrations in vitro, they have been proposed to be involved in regulating actin filament turnover in response to alteration of Ca2+ levels in plant cell ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.