Calcium Oscillations and its Functional Significance in
... DNA cleavage and contribute to cell killing80, Uncontrolled steady-state rise of [Ca2+]i can also induce Ca2+dependent activation of several genes that characterize many types of acute lethal injury. These genes can be induced within 15 min or less, as in the case of c-fos66 and c-jun, to trigger ad ...
... DNA cleavage and contribute to cell killing80, Uncontrolled steady-state rise of [Ca2+]i can also induce Ca2+dependent activation of several genes that characterize many types of acute lethal injury. These genes can be induced within 15 min or less, as in the case of c-fos66 and c-jun, to trigger ad ...
Stacks off tracks
... with the stability of the ER-Golgi connection. However, our observations also suggest the ...
... with the stability of the ER-Golgi connection. However, our observations also suggest the ...
Proceedings of the Indiana Academy of Science
... be followed in an orderly manner and that reproduceable results could be obtained. However, the difficulties of studying lytic phenomena with bacteria as the test organism are well known. In the early studies, qualitative expression of lysis as it progressed, or as it reached the end point (complete ...
... be followed in an orderly manner and that reproduceable results could be obtained. However, the difficulties of studying lytic phenomena with bacteria as the test organism are well known. In the early studies, qualitative expression of lysis as it progressed, or as it reached the end point (complete ...
Comparison of induction during development between Xenopus
... marker gene Xbra was detected at both low and high doses of activin. (B) RT-PCR analyses of animal cap explants treated with various doses of activin (0, 0.5, 1, 10, 100 ng/ml) for 1 hour at 20oC and cultured for 5 hours until sibling embryos reached stage 12 at 20oC. The expression of the organizer ...
... marker gene Xbra was detected at both low and high doses of activin. (B) RT-PCR analyses of animal cap explants treated with various doses of activin (0, 0.5, 1, 10, 100 ng/ml) for 1 hour at 20oC and cultured for 5 hours until sibling embryos reached stage 12 at 20oC. The expression of the organizer ...
Host cell interactions of outer membrane vesicle-associated
... endothelial cells (HBMEC), and renal glomerular endothelial cells (HRGEC) in a timedependent manner (Fig 2A, 2D and 2G). There were no significant differences between OMVs from NSF (5791/99) and SF (493/89) EHEC O157 strains, and OMVs containing (5791/99, 493/89) and lacking (493/89Δstx2a) Stx2a (Fi ...
... endothelial cells (HBMEC), and renal glomerular endothelial cells (HRGEC) in a timedependent manner (Fig 2A, 2D and 2G). There were no significant differences between OMVs from NSF (5791/99) and SF (493/89) EHEC O157 strains, and OMVs containing (5791/99, 493/89) and lacking (493/89Δstx2a) Stx2a (Fi ...
Preview the material
... The body’s ability to fight off infection using the immune system is dependent on several factors that are associated with both the immune system function and the type of pathogens that could infect the wound. If the patient is already immunocompromised, such as in the case of a cancer diagnosis, o ...
... The body’s ability to fight off infection using the immune system is dependent on several factors that are associated with both the immune system function and the type of pathogens that could infect the wound. If the patient is already immunocompromised, such as in the case of a cancer diagnosis, o ...
The yolk syncytial layer regulates myocardial
... Specific regions of the vertebrate extra-embryonic tissues have been shown to function as important signaling centers for early body patterning. In mammals, for example, the extra-embryonic anterior visceral endoderm (AVE) plays essential roles in forebrain induction (reviewed by Beddington and Robe ...
... Specific regions of the vertebrate extra-embryonic tissues have been shown to function as important signaling centers for early body patterning. In mammals, for example, the extra-embryonic anterior visceral endoderm (AVE) plays essential roles in forebrain induction (reviewed by Beddington and Robe ...
Inguinal hernia
... congenital or acquired gap in the abdominal wall or diaphragm (hernial orifice) through which the peritoneum (hernial sac), possibly together with parts of the intestines, protrudes.s are the most common. For example, in Germany each year some 275,000 people develop an inguinal herniaThe most common ...
... congenital or acquired gap in the abdominal wall or diaphragm (hernial orifice) through which the peritoneum (hernial sac), possibly together with parts of the intestines, protrudes.s are the most common. For example, in Germany each year some 275,000 people develop an inguinal herniaThe most common ...
Fibronectin and Other Adhesive Glycoproteins
... Fibronectin was first discovered in 1948 as a contaminant of plasma fibrinogen with insolubility at low temperature and was termed “cold-insoluble globulin” (Morrison et al. 1948; Mosesson and Umfleet 1970). Fibronectin is a high molecular weight dimeric glycoprotein (~450 kDa per dimer) widely expr ...
... Fibronectin was first discovered in 1948 as a contaminant of plasma fibrinogen with insolubility at low temperature and was termed “cold-insoluble globulin” (Morrison et al. 1948; Mosesson and Umfleet 1970). Fibronectin is a high molecular weight dimeric glycoprotein (~450 kDa per dimer) widely expr ...
The p57 CDKi integrates stress signals into cellcycle progression to
... In contrast, the p57T143A mutant was not phosphorylated by p38 (Figure 3A). Importantly, incubation of the cells with the p38 SAPK inhibitor SB203580 precluded p57 phosphorylation indicating that in vivo p57 phosphorylation required p38 activation (Figure 3B). To rule out that p57 phosphorylation wa ...
... In contrast, the p57T143A mutant was not phosphorylated by p38 (Figure 3A). Importantly, incubation of the cells with the p38 SAPK inhibitor SB203580 precluded p57 phosphorylation indicating that in vivo p57 phosphorylation required p38 activation (Figure 3B). To rule out that p57 phosphorylation wa ...
Interleukin 12 p40 Production by Barrier Epithelial Cells during
... SdV protein in tissue sections that were blocked with nonimmune rabbit serum and then incubated with rat anti-SdV Ab (1:750 vol/vol for 18 h at 4⬚C), biotinylated rabbit anti–rat IgG Ab, streptavidin-conjugated alkaline phosphatase complex, and red chromogen. In these experiments, the BAL fluid (wit ...
... SdV protein in tissue sections that were blocked with nonimmune rabbit serum and then incubated with rat anti-SdV Ab (1:750 vol/vol for 18 h at 4⬚C), biotinylated rabbit anti–rat IgG Ab, streptavidin-conjugated alkaline phosphatase complex, and red chromogen. In these experiments, the BAL fluid (wit ...
Collagen Diversity, Synthesis and Assembly
... due to the use of alternative transcriptional start sites. Collagen IX is covalently cross-linked to both collagens II and XI in the cartilage fibril, through lysine-derived cross-links; recent studies have shown how flexibility within the non-collagenous domains allows these cross-links to form (Ey ...
... due to the use of alternative transcriptional start sites. Collagen IX is covalently cross-linked to both collagens II and XI in the cartilage fibril, through lysine-derived cross-links; recent studies have shown how flexibility within the non-collagenous domains allows these cross-links to form (Ey ...
Airway surface liquid pH in well-differentiated airway - AJP-Cell
... recovery from acute ASL acidification or alkalization, 20–50 l of a perfluorocarbon suspension of HCl/NaOH (prepared by brief sonication) was added onto the ASL to change pH by 0.4–0.5 pH units. In some experiments, transport inhibitors were added to the perfusate or to both the perfusate and the A ...
... recovery from acute ASL acidification or alkalization, 20–50 l of a perfluorocarbon suspension of HCl/NaOH (prepared by brief sonication) was added onto the ASL to change pH by 0.4–0.5 pH units. In some experiments, transport inhibitors were added to the perfusate or to both the perfusate and the A ...
The Role of Scleraxis in Heart Valve Development and Disease
... United States, and is the most common cause of chronic mitral valve regurgitation (MVR) in developed countries. It is estimated that MVP affects more than 150 million people worldwide. When left untreated, MVP can lead to severe MVR resulting in a myriad of cardiac complications. The mortality rate ...
... United States, and is the most common cause of chronic mitral valve regurgitation (MVR) in developed countries. It is estimated that MVP affects more than 150 million people worldwide. When left untreated, MVP can lead to severe MVR resulting in a myriad of cardiac complications. The mortality rate ...
Chapter 1: Overview - Worcester Polytechnic Institute
... years, our phone conversations kept me going. Gracias mariscos! ...
... years, our phone conversations kept me going. Gracias mariscos! ...
YEAST STRESS RESPONSES DURING ACCLIMATION FOR
... imported from Limoux and Champagne. However, in the course of experiments, glass at the time was not so sturdy and would break easily under pressure. In his own factories, Merret claimed that he could produce bottles up to the task, making it possible for sparkling wine producers to keep moving forw ...
... imported from Limoux and Champagne. However, in the course of experiments, glass at the time was not so sturdy and would break easily under pressure. In his own factories, Merret claimed that he could produce bottles up to the task, making it possible for sparkling wine producers to keep moving forw ...
THE ROLE OF NODAL SIGNALING IN PATTERNING THE
... During embryonic development, a single cell generates the diverse array of cell types that comprise the adult body plan. Cells differentiate according to their position in the embryo in a highly reproducible fashion. Patterning is fundamental to establishing the spatial organization of the developin ...
... During embryonic development, a single cell generates the diverse array of cell types that comprise the adult body plan. Cells differentiate according to their position in the embryo in a highly reproducible fashion. Patterning is fundamental to establishing the spatial organization of the developin ...
Dentin-pulp complex
... Lymphocytes. No fat cell. Fibrous Matrix: Mostly reticular fibres and collagen fibres (Type I and Type III). Ground substance: Act as a medium to transport nutrients to cells and metabolites of the cell to the blood vessels. ...
... Lymphocytes. No fat cell. Fibrous Matrix: Mostly reticular fibres and collagen fibres (Type I and Type III). Ground substance: Act as a medium to transport nutrients to cells and metabolites of the cell to the blood vessels. ...
Roles of maltodextrin and glycogen phosphorylases in maltose
... Corynebacterium glutamicum transiently accumulates large amounts of glycogen, when cultivated on glucose and other sugars as a source of carbon and energy. Apart from the debranching enzyme GlgX, which is required for the formation of maltodextrins from glycogen, a-glucan phosphorylases were assumed ...
... Corynebacterium glutamicum transiently accumulates large amounts of glycogen, when cultivated on glucose and other sugars as a source of carbon and energy. Apart from the debranching enzyme GlgX, which is required for the formation of maltodextrins from glycogen, a-glucan phosphorylases were assumed ...
Patterson - Iowa State University
... To determine if there were discernable changes in the cells of the petal abscission zone, we observed both thin sections of the abscission zone (Fig. 2A) and scanning electron micrographs (Fig. 3). Light microscopy showed that all lines developed a typical abscission zone for the filament, petal, an ...
... To determine if there were discernable changes in the cells of the petal abscission zone, we observed both thin sections of the abscission zone (Fig. 2A) and scanning electron micrographs (Fig. 3). Light microscopy showed that all lines developed a typical abscission zone for the filament, petal, an ...
Induction and Fixation of Polarity -Early Steps in Plant Morphogenesis
... origins. This process includes a chain of basic events whereby two poles develop along an originally more or less homogeneous axis. Since the eighteenth century such phenomena are referred to by the term “polarity”. This concept simply designates the specific orientation of activity in space and inv ...
... origins. This process includes a chain of basic events whereby two poles develop along an originally more or less homogeneous axis. Since the eighteenth century such phenomena are referred to by the term “polarity”. This concept simply designates the specific orientation of activity in space and inv ...
Development of in vitro procedures that can predict the safety of
... TGN1412 immobilised onto polypropylene microtitre plates by “air-drying” stimulated cytokine release from PBMC. This technique was superior to other mAb immobilisation techniques, investigated in terms of predicting cytokine release. Immobilisation of TGN1412 may mimic the immunological synapse form ...
... TGN1412 immobilised onto polypropylene microtitre plates by “air-drying” stimulated cytokine release from PBMC. This technique was superior to other mAb immobilisation techniques, investigated in terms of predicting cytokine release. Immobilisation of TGN1412 may mimic the immunological synapse form ...
Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF
... and then exposed them to TNF. Sanguinarine was also added at the same time as 0 min and 5, 15, and 30 min after TNF. In every case, TNF was present for 30 min. As shown in Fig. 2C, coincubation of cells with sanguinarine and TNF was as effective as preincubation in blocking the activation of NF-kB. ...
... and then exposed them to TNF. Sanguinarine was also added at the same time as 0 min and 5, 15, and 30 min after TNF. In every case, TNF was present for 30 min. As shown in Fig. 2C, coincubation of cells with sanguinarine and TNF was as effective as preincubation in blocking the activation of NF-kB. ...
Utilization and Transport of Mannitol in Olea
... a 1 mannitol : 1 proton stoichiometry. Since such a mechanism would be associated with a net influx of positive charges into the cells, the effect of the dissipation of transmembrane electric potential on mannitol transport was studied. Fig. 4B shows the effect of the lipophilic cation tetraphenylph ...
... a 1 mannitol : 1 proton stoichiometry. Since such a mechanism would be associated with a net influx of positive charges into the cells, the effect of the dissipation of transmembrane electric potential on mannitol transport was studied. Fig. 4B shows the effect of the lipophilic cation tetraphenylph ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.