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... subsequent chain elongation requires the modification of specific lysine residues in consecutive ubiquitin moieties. In yeast, all seven lysine residues of ubiquitin are used for chain assembly, resulting in chains of different topology (Peng et al., 2003). However, only the functions of chains link ...
... subsequent chain elongation requires the modification of specific lysine residues in consecutive ubiquitin moieties. In yeast, all seven lysine residues of ubiquitin are used for chain assembly, resulting in chains of different topology (Peng et al., 2003). However, only the functions of chains link ...
Author`s post-print - Cardiff Metropolitan University
... biofilms, has increased the urgency to find effective antimicrobial interventions for wounds. Honey has been used topically in wound care for thousands of years. Its popularity waned in the 1970s as clinicians relied on antibiotics and more sophisticated dressings started to become available. Within ...
... biofilms, has increased the urgency to find effective antimicrobial interventions for wounds. Honey has been used topically in wound care for thousands of years. Its popularity waned in the 1970s as clinicians relied on antibiotics and more sophisticated dressings started to become available. Within ...
Spatial Reorganization of Glycogen Synthase upon Activation in 3T3
... then with secondary antibodies coupled to Alexa Fluor 633 (antimouse; red) or 488 (antirabbit; green). Cells were then analyzed by confocal microscopy. B, 3T3-L1 adipocytes plated on glass coverslips were preincubated for 2.5 h in DMEM containing 5 mM glucose and 0.5% FBS. Replicate wells were treat ...
... then with secondary antibodies coupled to Alexa Fluor 633 (antimouse; red) or 488 (antirabbit; green). Cells were then analyzed by confocal microscopy. B, 3T3-L1 adipocytes plated on glass coverslips were preincubated for 2.5 h in DMEM containing 5 mM glucose and 0.5% FBS. Replicate wells were treat ...
Lecture 9 - Fatty Acid Metabolism
... • Ruminal growth and cellular differentiation • A major shift in the pattern of nutrients being ...
... • Ruminal growth and cellular differentiation • A major shift in the pattern of nutrients being ...
PIN-Dependent Auxin Transport: Action, Regulation
... nondirectional stream in the phloem along with photosynthetic assimilates, and second, slow and directional cell-to-cell polar auxin transport (PAT). While phloem transport provides a general way to deliver auxin from the sites of its synthesis (mostly in young leaves) to recipient organs, PAT distr ...
... nondirectional stream in the phloem along with photosynthetic assimilates, and second, slow and directional cell-to-cell polar auxin transport (PAT). While phloem transport provides a general way to deliver auxin from the sites of its synthesis (mostly in young leaves) to recipient organs, PAT distr ...
PATELLIN1/2 interact with CVL1 and CVP2 to regulate vascular
... The structure and function of vascular tissue In order for terrestrial plants to grow more than a few centimeters from the ground, evolution of specialized vascular tissue was required (Raven, 1993). The veins formed by the vascular tissue provide mechanical support and carry water from the parts of ...
... The structure and function of vascular tissue In order for terrestrial plants to grow more than a few centimeters from the ground, evolution of specialized vascular tissue was required (Raven, 1993). The veins formed by the vascular tissue provide mechanical support and carry water from the parts of ...
Downloaded - The Journal of Cell Biology
... adhered strongly to cadherin-coated substrates, and this promoted lateral clustering of cadherins, whereas a cadherin with the -cat–binding site but not the JM domain failed to promote either strong adhesion or lateral clustering. These data contrast with those of Ozawa and Kemler (1998), suggestin ...
... adhered strongly to cadherin-coated substrates, and this promoted lateral clustering of cadherins, whereas a cadherin with the -cat–binding site but not the JM domain failed to promote either strong adhesion or lateral clustering. These data contrast with those of Ozawa and Kemler (1998), suggestin ...
understanding the role of sumoylation in regulating lkb1 function
... interest in my growth, input, and discussion every time we meet in meetings and in public is greatly cherished. Dr. Hui-Kuan Lin, you have also been there for me since my first year in graduate school. I learned a lot of techniques in your lab during my rotation with you. Also, thank you for the val ...
... interest in my growth, input, and discussion every time we meet in meetings and in public is greatly cherished. Dr. Hui-Kuan Lin, you have also been there for me since my first year in graduate school. I learned a lot of techniques in your lab during my rotation with you. Also, thank you for the val ...
EIR 18 - Universitätsklinikum Tübingen
... often referred to as bad guys, exercise, although also associated with M2 formation, is known to be beneficial in several tumour entities. This apparent paradox of the M2 subtype may be a suitable topic for future research in our field. The last paper is an extension of a previously published study ...
... often referred to as bad guys, exercise, although also associated with M2 formation, is known to be beneficial in several tumour entities. This apparent paradox of the M2 subtype may be a suitable topic for future research in our field. The last paper is an extension of a previously published study ...
... [58]. At present, the most important deactivating cytokines are IL-10 and transforming growth factor-β (TGFβ). IL-4 has an intermediate position, since some macrophage functions are induced by IL-4 (major histocompatibility complex (MHC) class II expression) and others are inhibited, e.g. production ...
Receptor-Like Activity Evoked by Extracellular ADP in Arabidopsis
... phatases, and adenosine nucleosidases with retrieval of adenine (the ultimate hydrolytic product) by PM purine permeases (Komoszyński, 1996; Steinebrunner et al., 2003; Wu et al., 2007; Riewe et al., 2008a, 2008b; Govindarajulu et al., 2009; Clark et al., 2010b; Liang et al., 2010). Manipulation of ...
... phatases, and adenosine nucleosidases with retrieval of adenine (the ultimate hydrolytic product) by PM purine permeases (Komoszyński, 1996; Steinebrunner et al., 2003; Wu et al., 2007; Riewe et al., 2008a, 2008b; Govindarajulu et al., 2009; Clark et al., 2010b; Liang et al., 2010). Manipulation of ...
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... The LIM-HD gene tailup (tup; also known as islet) has been categorised as a prepattern gene that antagonises the formation of sensory bristles on the notum of Drosophila by downregulating the expression of the proneural achaete-scute genes. Here we show that tup has an earlier function in the develo ...
... The LIM-HD gene tailup (tup; also known as islet) has been categorised as a prepattern gene that antagonises the formation of sensory bristles on the notum of Drosophila by downregulating the expression of the proneural achaete-scute genes. Here we show that tup has an earlier function in the develo ...
Ca signaling and early embryonic patterning during zebrafish
... primary germ layers and body axes. 3. Data are presented to support our proposal that intracellular Ca2+ waves are an essential feature of embryonic cytokinesis, and that propagating intercellular Ca2+ waves (both long and short range), may play a crucial role in: (a) the establishment of the embryo ...
... primary germ layers and body axes. 3. Data are presented to support our proposal that intracellular Ca2+ waves are an essential feature of embryonic cytokinesis, and that propagating intercellular Ca2+ waves (both long and short range), may play a crucial role in: (a) the establishment of the embryo ...
Influence of the 4G/5G PAI-1 genotype on angiotensin II
... Because endothelial PAI-1 is an important source for PAI1 levels in plasma and there is evidence that genetic factors may be important in determining inhibitor levels, we investigated whether the PAI-1 response by endothelial cells challenged with Ang II is related to the 4G/5G genotype, and whether ...
... Because endothelial PAI-1 is an important source for PAI1 levels in plasma and there is evidence that genetic factors may be important in determining inhibitor levels, we investigated whether the PAI-1 response by endothelial cells challenged with Ang II is related to the 4G/5G genotype, and whether ...
VARICOSE, a WD-domain protein, is required for leaf
... defects (Okada et al., 1991; Ruegger et al., 1997). Leaf development is also perturbed by growing wild-type plants in the presence of polar auxin transport inhibitors (Mattsson et al., 1999; Sieburth, 1999). Furthermore, some auxin-resistant mutants, such as axr1 and axr2-1, have disrupted auxin res ...
... defects (Okada et al., 1991; Ruegger et al., 1997). Leaf development is also perturbed by growing wild-type plants in the presence of polar auxin transport inhibitors (Mattsson et al., 1999; Sieburth, 1999). Furthermore, some auxin-resistant mutants, such as axr1 and axr2-1, have disrupted auxin res ...
The Influence of Certain Trace Metals on Bacterial
... French press, was used in preference to the more conventional procedures for the disintegration of the labelled organisms. The homogenates were treated with DNAse (I pg./ml.; Sigma Chemical Co., London; RNAse-free) for 5 min. at room temperature and then centrifuged at 4" for 10min. at 18,000 g . Th ...
... French press, was used in preference to the more conventional procedures for the disintegration of the labelled organisms. The homogenates were treated with DNAse (I pg./ml.; Sigma Chemical Co., London; RNAse-free) for 5 min. at room temperature and then centrifuged at 4" for 10min. at 18,000 g . Th ...
Development of Competitive Direct Enzyme
... detection of gentamicin residues in milk, urine, blood, and tissue including microbioassay (Lantz et al., 1980; Rosner and Aviv, 1980), gas chromatography (GC; Isoherranen and Soback, 1999), and high-performance liquid chromatography (HPLC; Stead and Richards, 1996, 1997; Graham et al., 1997). Moreo ...
... detection of gentamicin residues in milk, urine, blood, and tissue including microbioassay (Lantz et al., 1980; Rosner and Aviv, 1980), gas chromatography (GC; Isoherranen and Soback, 1999), and high-performance liquid chromatography (HPLC; Stead and Richards, 1996, 1997; Graham et al., 1997). Moreo ...
Direct Interaction between Survivin and Smac/DIABLO Is Essential
... Survivin (Surv-BIR) lacking its C-terminal and Smac/DIABLO were also cloned into pEGFP-C1 plasmid, respectively. In addition, the gene fragments (reacted by PCR for primer pairs P12/P1) was used to generated pTRE2/A-Surv (coding for antisense Survivin). The DNA fragment coding for mature Smac/DIABLO ...
... Survivin (Surv-BIR) lacking its C-terminal and Smac/DIABLO were also cloned into pEGFP-C1 plasmid, respectively. In addition, the gene fragments (reacted by PCR for primer pairs P12/P1) was used to generated pTRE2/A-Surv (coding for antisense Survivin). The DNA fragment coding for mature Smac/DIABLO ...
Classification of Enteric Progenitors in Zebrafish During Development
... • Intrinsic innervation of the intestinal tract • Modulates gut function • Functions autonomously from Central nervous system • Composed of different subtypes of neurons and glial cells ...
... • Intrinsic innervation of the intestinal tract • Modulates gut function • Functions autonomously from Central nervous system • Composed of different subtypes of neurons and glial cells ...
CalS7 encodes a callose synthase responsible for callose
... plasmodesmatal region, but is removed when the pore attains its final size. A drastic amount of callose deposition around the sieve pores can also be rapidly induced by mechanical injury, chemical treatments and physiological stress conditions (Sjölund, 1997; Evert, 2006), which has been used as ev ...
... plasmodesmatal region, but is removed when the pore attains its final size. A drastic amount of callose deposition around the sieve pores can also be rapidly induced by mechanical injury, chemical treatments and physiological stress conditions (Sjölund, 1997; Evert, 2006), which has been used as ev ...
The Structure of Collagen within Parchment
... display elastic qualities at the macroscopic level11' 36. However, there is no evidence for elasticity in the type III collagen molecule itself. The fibrils in tissues with type I and type III collagen present are typically composed of 80% type I molecules and 20% type III molecules. Type I collagen ...
... display elastic qualities at the macroscopic level11' 36. However, there is no evidence for elasticity in the type III collagen molecule itself. The fibrils in tissues with type I and type III collagen present are typically composed of 80% type I molecules and 20% type III molecules. Type I collagen ...
Animal Models in Eye Research
... of the greatest debates in the eye field is how many times eyes have evolved independently during evolution and if there is a common ancestor. Based on the different types, it is obvious that eyes have evolved more than once. Also embryology teaches us that in different species eyes derive from diff ...
... of the greatest debates in the eye field is how many times eyes have evolved independently during evolution and if there is a common ancestor. Based on the different types, it is obvious that eyes have evolved more than once. Also embryology teaches us that in different species eyes derive from diff ...
Core-specific adaptive regulatory T-cells in
... CD4+ Treg -cells (regulatory T-cells) probably contribute to the impaired virus-specific T-cell responses in chronic HCV (hepatitis C virus) infection; however, their antigen-specificity has remained elusive. In the present study, we analysed peripheral blood CD4+ Treg -cells in patients with chroni ...
... CD4+ Treg -cells (regulatory T-cells) probably contribute to the impaired virus-specific T-cell responses in chronic HCV (hepatitis C virus) infection; however, their antigen-specificity has remained elusive. In the present study, we analysed peripheral blood CD4+ Treg -cells in patients with chroni ...
- Wiley Online Library
... involves self-limiting gastrointestinal symptoms in otherwise healthy individuals but can also develop into more systemic conditions, primarily affecting the brain as well as the fetus in pregnant women (Allerberger and Wagner, 2010). In such severe invasive cases, mortality rates of up to 30% have ...
... involves self-limiting gastrointestinal symptoms in otherwise healthy individuals but can also develop into more systemic conditions, primarily affecting the brain as well as the fetus in pregnant women (Allerberger and Wagner, 2010). In such severe invasive cases, mortality rates of up to 30% have ...
Responses of plant vascular systems to auxin transport
... The vascular tissues of plants form an interconnected system of continuous cell files throughout the plant body (Esau, 1965; Nelson and Dengler, 1997). Two types of conducting tissues, phloem and xylem, are capable of transporting aqueous solutions of photoassimilates and minerals through tubes of a ...
... The vascular tissues of plants form an interconnected system of continuous cell files throughout the plant body (Esau, 1965; Nelson and Dengler, 1997). Two types of conducting tissues, phloem and xylem, are capable of transporting aqueous solutions of photoassimilates and minerals through tubes of a ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.