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Science Course: Pre-AP Biology Unit: Non-Mendelian Genetics DNA Structure and DNA Replication Protein Synthesis Genetic Mutations TEKS/Prerequisites Guiding Assessment Questions/ Specificity Designated Grading Period: Third Grading Period Days to teach: 10A days, 11B days Vocabulary Unit Topic: Non-Mendelian Genetics 6F Predict possible outcomes of various genetic combinations such as monohybrid crosses, dihybrid crosses and non Mendelian inheritance (EOC Readiness Standard) D. Molecular Genetics and Heredity 1. Understand Mendel’s Laws of Inheritance 2. Know modifications of Mendel’s laws. (College and Career Readiness Standards) How are autosomal traits, including recessive genetic disorders that are carried in a population, related to Mendel’s observations of heredity? How is incomplete dominance expressed in a phenotype? Codominance? How is a male offspring’s phenotype affected if he inherits a recessive autosomal allele? A recessive sexlinked allele? How is autosomal and sex-linked inheritance similar in heterozygous female offspring? Revised Spring 2016 Instructional Strategies/ELPS Resources/Weblinks Days to Teach: 2 days The inheritance of phenotypic traits that depend on many genes is called _____. a. dominant inheritance b. incomplete inheritance c. polygenic inheritance d. codominant inheritance Carrier, sex-linked gene, X chromosome inactivation, incomplete dominance, codominance, polygenic trait, pedigree analysis Activities Non-Mendelian Inheritance http://www.ck12.org/biol ogy/Non-MendelianInheritance/ http://www.ck12.org/biol ogy/Non-MendelianInheritance/lesson/NonMendelian-InheritanceBIO/ 1A KWL Analogy Perceptive Based Activities ELPS/Strategies http://ritter.tea.state.tx.us/ rules/tac/chapter074/ch07 4a.html 2D Graphic Organizer 1C Self Assess of think pair share 4F Venn diagram autosomal vs sex-linked genes (pg 206 TE) United Streaming Video: Biologix: Alternate Patterns of Inheritance (29:07) 6F – Non mendelian inheritance video: https://www.youtube.com/watch?v =BYMwb3b10Ac Sex-linked inheritance https://www.biologycorner.com/wo rksheets/genetics_xlinked.html APPS: I Tunes U – TASA Bio Holt Pre-AP Skillsheets: Chapter 6 Unit 3 Project- Interpreting a Pedigree Science Course: Pre-AP Biology Unit: Non-Mendelian Genetics DNA Structure and DNA Replication Protein Synthesis Genetic Mutations TEKS/Prerequisites Guiding Assessment Questions/ Specificity Designated Grading Period: Third Grading Period Days to teach: 10A days, 11B days Vocabulary Instructional Strategies/ELPS Unit Topic: DNA Structure and DNA Replication 6A Identify components of DNA, and describe how information for specifying the traits of an organism is carried in the DNA. (EOC Readiness Standard) (College and Career Readiness Standards) 5C Describe the roles of DNA, ribonucleic acid (RNA), and environmental factors in cell differentiation. (EOC Supporting Standard) D. Molecular Genetics and Heredity 3. Understand the molecular structures and functions of nucleic acids. (College and Career Readiness Standards) 6B Recognize that components that make up the genetic code are common to all organisms. (EOC Supporting Standard) Revised Spring 2016 What is the composition of DNA? Resources/Weblinks Days to Teach: 3 days Activities DNA: Identification of Components Using Color: http://biologycorner.com/ worksheets/DNAcoloring. html United Streaming Video: Biologix: DNA Replication (29:07) Specificity: Emphasize: nucleotide composition, DNA shape, differences between DNA and RNA, and the definition of a genome ELPS/Strategies http://ritter.tea.state.tx.us/ rules/tac/chapter074/ch07 4a.html Safari Montage: Secret of Photo 51 (55:02) Investigate Griffith’s “transforming principle” experiment DNA Knex How is genetic information carried by DNA? Molecules of DNA are constructed from long chains of a. amino acids b. fatty acids c. monosaccharides d. nucleotides Bacteriophage, nucleotide, complementary base pair, replication, double helix, DNA helicase, DNA polymerase 5B Manipulatives 2G Questioning Answers DNA tic tac toe DNA ReplicationsSNORK Activity Create timeline DNA discoveries and the scientist responsible (pg 220 TE) DNA to Protein Website: http://learn.genetics.utah.edu/conte nt/begin/dna/ Video—RACE FOR THE DOUBLE HELIX 6A – DNA Structure Video: http://www.youtube.com/watch?v= 8kK2zwjRV0M&edufilter=_2nXF UMaB1_cnY78uKT5qQ Science Course: Pre-AP Biology Unit: Non-Mendelian Genetics DNA Structure and DNA Replication Protein Synthesis Genetic Mutations TEKS/Prerequisites Guiding Assessment Questions/ Specificity Designated Grading Period: Third Grading Period Days to teach: 10A days, 11B days Vocabulary Instructional Strategies/ELPS Unit Topic: Protein Synthesis Days to Teach: 4 Days 6C Explain the purpose and process of transcription and translation using models of DNA and RNA. How does DNA instruct the body to make protein? (EOC Supporting Standard) (College and Career Readiness Standards) Why might redundancy in the genetic code be an advantage to a cell? 6D Recognize that gene expression is a regulated process. (EOC Supporting Standard) Molecular Genetics and Heredity 3. Understand the molecular structures and functions of nucleic acids. (College and Career Readiness Standards) Revised Spring 2016 Resources/Weblinks Specificity: Emphasize: location of Transcription and Translation Rule of tRNA and mRNA How to use a Codon chart Review 9A- structure of a protein Example of gene expression During transcription, A proteins are synthesized b. DNA is replicated c. RNA is produced. d. translation occurs In order for translation to occur, mRNA must migrate to the a. ribosomes b. lac operon c. RNA polymerase Students are expected to know the following vocabulary terms: RNA Transcription Translation Gene expression Messenger RNA Transfer RNA Ribosomal RNA Codon Anticodon d. enhancer Genetic code Operon Intron Exon Activities Laying the Foundation Lab 23: The trp Operon Modeling Gene Regulation DNA, RNA, & Snorks http://www.biologycorner .com/worksheets/DNA_s norks.html Text: Biology, Holt, 2015 United Streaming Video: Biologix: Transcription of DNA to Messenger RNA (29:07) United Streaming Video: Biologix: Translation and Protein Synthesis (29:07) DNA Extraction Lab Codon Card activity Protein Synthesis http://www.auroraschools.org/userfiles/414/Classes/1 088/protein%20synthesis%20web% 20activity.doc Codon Bingo APPS: I Tunes U – TASA Bio DNA Puzzle Activity Transcription/Translation ELPS/Strategies http://ritter.tea.state.tx.us/ rules/tac/chapter074/ch07 4a.html 4 Column Comparison of different of different RNA (pg. 236 TE) 2I Accountable 1G Scanning Transcription comic strip (pg 230 TE) Science Course: Pre-AP Biology Unit: Non-Mendelian Genetics DNA Structure and DNA Replication Protein Synthesis Genetic Mutations TEKS/Prerequisites Guiding Assessment Questions/ Specificity Designated Grading Period: Third Grading Period Days to teach: 10A days, 11B days Vocabulary Instructional Strategies/ELPS Unit Topic: Mutation 6E Identify and illustrate changes in DNA and evaluate the significance of these changes. (EOC Readiness Standard) D. Molecular Genetics and Heredity 2. Know modifications to Mendel’s Laws. (College and Career Readiness Standards) Days to Teach: 2 Days How do changes in DNA affect the resulting protein? What are the implications of these changes? When does a deletion or an insertion not result in a frame shift? Specificity: Emphasize: Duplication, Insertion, Translocation, and Inversion, Revised Spring 2016 Resources/Weblinks A mutation caused by a piece of DNA breaking away from its chromosome and becoming attached to a nonhomologous chromosome is called a.deletion b.duplication c.inversion d.translocation Point mutation, Deletion, Insertion, Activities Mutations Activity: http://www.biologyjuncti on.com/Monstrous%20M utations.doc Frame shift Mutation ELPS/Strategies http://ritter.tea.state.tx.us/ rules/tac/chapter074/ch07 4a.html 3E Manipulative 2G Questioning Answers Mutations Activity Text: Biology, Holt, 2015 http://www.biologyjunction.com/M onstrous%20Mutations.doc 6E – DNA Mutations Video: http://www.youtube.com/watch?v= efstlgoynlk&edufilter=_2nXFUMa B1_cnY78uKT5qQ APPS: I Tunes U – TASA Bio