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Environment and Gene Expression Scientists have learned that gene expression (transcription and translation) can be regulated. It is now clear that not all genes are expressed in every cell, nor are many genes expressed all of the time. Cells have complex systems that regulate whether or not specific genes are expressed. Expression depends on the cell’s need and environment. Through gene regulation, a given sequence can be expressed in different ways - in different bodies or tissues, under different conditions, or at different times. Thus, gene regulation accounts for changes during development as well as differences among organisms that have similar genes. One benefit of gene regulation is that cells can use energy and materials efficiently. Recall that many steps take place in the expression of a gene. Also, other molecules play a role in the processes. Because complex interactions happen at each step, there are many opportunities to regulate gene expression. So, nearly every step in the process of gene expression can be regulated or controlled. A molecular system that controls the expression of a specific gene is called a genetic switch. Like a light switch, a genetic switch can be turned “on” or “off.” Often, the switch is triggered by the factors or conditions outside the cell. Also, the product of one gene may serve to regulate another gene in the same organism. The development and expression of an inherited trait can be influenced by environmental factors such as nutrients, temperature, sunlight, and so on. The relationship between gene expression and environmental influence can be seen in the following example. Temperature affects fur color in the Himalayan rabbit. Under normal circumstances, these rabbits are white with black ears, nose, tail, and feet. (The black fur helps the rabbit absorb more heat in its extremities.) However, when some of the white fur on a Himalayan rabbit’s back is shaved off and the area is kept covered with an ice pack, the new hairs grow in black. The change in temperature produces a change in fur color. Temperature, an environmental factor, altered the expression of the gene. Another example involves plants. Remember that plants are green because chlorophyll produces a green color during photosynthesis, a process which requires sunlight. When parts of a leaf are covered with dark paper, chlorophyll production stops in the area that is covered. Only the exposed part produces chlorophyll, is green, and performs photosynthesis. Again, a change in the environment altered the expression of the gene. Stress and nutrition can also affect gene expression. For example, someone who has a tall genotype may not develop a tall phenotype if his or her growth is stunted by malnutrition. Copy and complete the following questions in your notebook: 1. What is meant by the term gene regulation? 2. What are some of the environmental factors that can regulate genes? 3. Explain two examples of how environmental factors can influence gene expression.