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Name_____________________ Hour ____Date ___________ DNA WebQuest To Start: Go to Ms. Stash’s webpage: http://www.sps186.org/teachers/stash/?b=52 home page gives you the link to this assignment in electronic form so that you can directly click on the links and go straight to the websites. Otherwise, you can just type the link into your browser. Website #1: DNA Replication and Protein Synthesis Go to PBS DNA Workshop (http://bitly.com/pbsdna) Click “DNA replication” (upper left) and then click “unzip.” Read the script (text), answer the questions below, and then click “OK.” 1. In a real cell, what does the DNA molecule do before it unzips? 2. What molecules break the rungs (bases) apart? Drag the correct bases over to “synthesize” the new DNA halves. Read the script, answer the questions below and then click “OK.” 3. How many base pairs are in the real human genome? Click “protein synthesis” (upper right). Click “unzip.” 4. How much of the DNA molecule actually unzips in a real cell? Base Pair the nucleotides for just one half of the DNA. Read script, answer questions below, click “OK.” 5. About how many bases would a real mRNA molecule have? 6. Where does the mRNA go now? Match the tRNA molecules to their base pair nucleotides on the mRNA. Answer the questions. 7. Which molecule has the codons? 8. Which molecule has the anti-codons? 9. What molecules are attached to the tRNAs? Click “OK” and continue matching the tRNAs. Read script, answer questions below, click “OK.” 10. Where does the first tRNA go? Continue matching and answer questions. 11. How long will a real polypeptide chain get to be? 12. When does translation of the mRNA end? Website #2: Protein Synthesis Go to Genetics Science Learning Center (http://learn.genetics.utah.edu/content/basics/transcribe/ ) Click the button that says “click here to begin.” Use the keyboard to type the bases that would form the mRNA. Follow the instructions to determine the order of the amino acids. 13. List the order of your amino acids. 14. How did the process know to end? Read the script on the rest of the webpage. 15. Describe the process of transcription. 16. Describe the process of translation. Website #3: Mutation Go to Understanding Evolution (http://bitly.com/evomutate) Read the information and fill out the table below: Type of Mutation Description Effect on resulting protein Substitution Insertion Deletion Frameshift Website #4: Replication Go to Nobel Prize (http://bitly.com/nobeldna) Click on the arrow to play the “DNA the Double Helix” game; Click “next” and reading each page, continue to click next until you come to the game. Click on organism #1 and match the base pairs as fast you can! Click “next” and then click on the organism you identify that belongs to chromsome #1; continue playing the game with the other two chromosomes, filling in the chart below. Be careful, other teams may get different results. Chromosome # 1 2 3 How many chromosomes? How many base pairs? How many genes? What is the organism?