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4 Steps of DNA Replication •Step 1: Enzymes break the hydrogen bonds between the base pairs, causing the 2 chains to separate like a zipper •Step 2: Each chain serves as a pattern. Free nucleotides in the nucleus pair with bases on the chains; A-T, G-C. • Step 3: As the pairs bond, an enzyme links the phosphate of each nucleotide to the sugar of the previous one. • Step 4: The pairing and bonding continue until the original two DNA chains are made into new paired chains. Protein Synthesis • Transcription: “transcribing” the sequence of DNA bases that “codes” for a single protein (a gene) into a molecule of mRNA. Steps • Step 1: “unzip” that part of DNA that codes for a specific protein. • Step 2: “transcribe” the sequence of bases in the DNA “antisense” strand into a complimentary mRNA strand. • Step 3: mRNA moves off of the DNA and enzymes “re-zip” the DNA. • ALL 3 forms of RNA are formed by the process of Transcription: mRNA, tRNA, and rRNA. Translation • Changing (translating) the genetic code of mRNA (each codon specifies one of the 20 amino acids) into a functional protein. • Occurs at a ribosome.