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Transcript
X-linked, Multifactorial, and Epistasis Problems Instructions: Answer the following genetics problems using 5 steps. (Assign symbols, show the genotypes of the parents, make the Punnett square, show the genotypes of the offspring and show the phenotypes of the offspring. 1. In humans, the gene for color vision is dominant over the gene for colorblindness. This gene is located on the X chromosome. Cross a man who has normal vision with a woman who is colorblind. 2. In humans, the gene for the production of dystrophin (a muscle protein) is dominant to the gene for a lack of dystrophin (which causes Duchenne muscular dystrophy.) The gene is found on the X chromosome. Cross a normal man with a woman who is a carrier (heterozygous.) 3. In humans, the gene for blood clotting is dominant to the gene for hemophilia. The gene is found on the X chromosome. Cross a woman who is homozygous normal with a hemophiliac man. 4. Height in a plant called spike weed is a multifactorial trait. Three gene pairs are involved, each adding an additional 5 cm to the base plant height. (i.e. they are quantitative characters.) The smallest a spike weed can be (its base height) is 10 cm and its genotype would be aabbcc. Cross with a plant that is aabbcc and a plant that is AABBCC? What are the genotype(s) and phenotype(s) of the offspring? 5. One strain of the silkworm (Bombyx mori) lays white eggs, another lays pink, and still another black. The allele for black eggs is dominant to the allele for pink eggs and the allele for white is epistatic to black (this tells you that if you have the dominant white gene (W) and the dominant black gene (B) the white phenotype will hide the expression of the black phenotype). Cross two heterozygous white egg laying silkworms (WwBb) and indicate the phenotypes of the offspring.
