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Interworkings of Current Project Functional Genomics Functional genomics Expression profiling Signaling/pathways Structural Genomics R gene identification & analysis/ Evolution Baker, Brown, May, Bradeen, Jahn Training/ Outreach Jiang, Buell, Baker Resource generation R genes Transgenic lines Expression profiles Arrays Bioinformatic Resources Buell, Jiang, May Utilizing a diverse scientific community to study intensive and important topics using comparative genomics with the Solanaceae as it provides a unique set of crop species that is important to: -Investigate plant response to abiotic stress, biotic stress and development (done) -Integrative team of geneticists, breeders, genomicists, bioinformaticists, biologists to be poised to tackle important issues in translational genomics as it pertains to the Solanaeae (done) -Ready to move to more applications in the field, breeding, basic biology, evolution Present Past Resource oriented R genes ESTs First generation arrays Baker, May, Jiang, Tanksley, Fry, Helgeson Second generation resources (R genes from other species, loci) Expression profiles from diverse physiological states Comparative genomics at structural and functional levels Linking breeding with genomics Baker, Jiang, Buell, May, Brown, Jahn, Bradeen Future Allele/gene prospecting of germplasm Translational genomics to generate R gene banks for major diseases in Solanaceae Whole genome comparative genomics Focus on important potato biology