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Hox Genes During development cells don’t just grow and divide they under go differentiation (cells become specialized in structure and function). Hox genes “master control genes”= control the differentiation of cells and tissue in a developing embyro.(tell the cells in the body what to become…..arm, leg, eyes….these genes control the development of our head-to-tail anatomy) Careful control of expression in these genes is important for normal development in the embryo A mutation in the hox gene “master control gene” can completely change the organs that develop in specific parts of the body.