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Cells Discovery of Cells Cells were discovered in 1665 by Robert Hooke. Early studies of cells were conducted by - Mathias Schleiden (1838) - Theodor Schwann (1839) Schleiden and Schwann proposed the Cell Theory. 2 Cell Theory 1. All organisms are composed of cells. 2. Cells are basic units of structure and function. 3. Cells arise only from pre-existing cells. 3 Cell size is limited. -As cell size increases, it takes longer for material to diffuse from the cell membrane to the interior of the cell. Surface area-to-volume ratio: as a cell increases in size, the volume increases 10x faster than the surface area 4 5 Microscopes are required to visualize cells. Light microscopes can resolve structures that are 200nm apart. Electron microscopes can resolve structures that are 0.2nm apart. 6 3 Main Parts of All Cells All cells have certain structures in common. 1. genetic material – in a nucleoid or nucleus 2. cytoplasm – a semi fluid matrix 3. plasma membrane – a phospholipid bilayer 7 Prokaryotic Cells Pro = before Karyote = nucleus Prokaryotic cells lack a membranebound nucleus. -genetic material is present in the nucleoid Example – types of bacteria 8 Prokaryotic Cells Prokaryotic cells possess -cell walls -genetic material in the nucleoid - cytoplasm -plasma membrane -ribosomes -no membrane-bound organelles 9 Prokaryotic Cells 10 Prokaryotic Cells Flagella -present in some prokaryotic cells -used for locomotion -rotary motion propels the cell 11 Eukaryotic Cells Eu = true Karyote = nucleus Eukaryotic cells -possess a membrane-bound nucleus -are more complex than prokaryotic cells -compartmentalize many cellular functions within organelles -possess a cytoskeleton for support and to maintain cellular structure 12 Eukaryotic Cells 13 Eukaryotic Cells 14 Eukaryotic Cells Nucleus -stores the genetic material of the cell in the form of multiple, linear chromosomes -surrounded by a nuclear envelope composed of 2 phospholipid bilayers -in chromosomes – DNA is organized with proteins to form chromatin - Nucleolus – makes ribosomes 15 Eukaryotic Cells 16 Eukaryotic Cells • Add to Notes: • Plasma (cell) membrane – controls what enters and leaves the cell. Is made up of a lipid bilayer (two layers of lipids and proteins).(Semi-permeable) • Vesicle - organelles that separate and transport material within a cell. Used for storage, transport, and secretion. 17 Eukaryotic Cells Ribosomes -the site of protein synthesis in the cell -composed of ribosomal RNA and proteins -found within the cytosol of the cytoplasm and attached to internal membranes (rough ER) 18 Rough endoplasmic reticulum (RER) -membranes that create a network of channels throughout the cytoplasm -attachment of ribosomes to the membrane gives a rough appearance -synthesis of proteins to be secreted, sent to lysosomes or plasma membrane 19 Smooth endoplasmic reticulum (SER) -relatively few ribosomes attached -functions: -synthesis of membrane lipids -calcium storage -detoxification of foreign substances 20 21 Golgi apparatus (Golgi Body) -flattened stacks of interconnected membranes -packaging and distribution of materials (mainly proteins) to different parts of the cell -synthesis of cell wall components - Proteins made by ribosomes go to Golgi to be folded! 22 23 Lysosomes -membrane bound vesicles containing digestive enzymes to break down macromolecules -destroy cells or foreign matter - Breaks down malfunctioning organelles 24 lysosome 25 Vacuoles -membrane-bound structures with various functions depending on the cell type – overall function is to store food, water, or waste There are different types of vacuoles: -central vacuole in plant cells (stores water – turgor pressure) -contractile vacuole of some protists (expels water from organism) 26 27 Mitochondria -organelles present in all types of eukaryotic cells -contain enzymes for transferring the energy (cell respiration) -found in all types of eukaryotic cells 28 Mitochondria -surrounded by 2 membranes -contain their own DNA 29 Mitochondria 30 Chloroplasts Chloroplasts -organelles present in cells of plants and some other eukaryotes -contain chlorophyll for photosynthesis - Two parts: granum (thylakoids) and Stroma 31 Chloroplasts 32 Centrosome Composed of TWO cylindrically shaped centrioles. Centrioles are perpendicular Creates spindle fibers that help the cell divide. Each contain microtubules that help organize cilia and flagella. 33 Cytoskeleton Cyto = cell -network of protein fibers found in all eukaryotic cells -supports the shape of the cell -keeps organelles in fixed locations -helps move materials within the cell 34 Cytoskeleton Cytoskeleton fibers include -actin filaments – responsible for cellular contractions, crawling, “pinching” -microtubules – provide organization to the cell and move materials within the cell - filaments – provide structural stability 35 Cytoskeleton 36 Cell Movement Cell movement takes different forms. -Crawling is accomplished filaments. -Flagella ripple to move a cell. long, few in number -Cilia can be arranged in rows on the surface of a eukaryotic cell to propel a cell forward. short, numerous 37 Cell Movement 38 Extracellular Structures Extracellular structures include: -cell walls of plants, fungi, some protists -extracellular matrix surrounding animal cells 39 Extracellular Structures Cell walls -present surrounding the cells of plants, fungi, and some protists -the carbohydrates present in the cell wall vary depending on the cell type: -plant and protist cell walls cellulose -fungal cell walls - chitin 40 Extracellular Structures 41 42 43