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Transcript
Common (Wild-Type) Allele and 4 Types of Genetic Polymorphisms DNA polymorphisms include deletions, in which a DNA sequence is missing compared with the common allele, and insertions, in which a DNA sequence is added compared with the common allele. Repeats may also occur in which the same sequence repeats multiple times. Depending on the size of the repeating unit and the number of repeats, these variants may have different names, such as satellites, microsatellites, minisatellites, or copy number variants. Single-nucleotide polymorphisms (SNPs), variations at a single base-pair location, are the most common type of polymorphism in the human genome. Source: How to Use an Article About Genetic Association, Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed Citation: Guyatt G, Rennie D, Meade MO, Cook DJ. Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed; 2015 Available at: http://mhmedical.com/ Accessed: August 11, 2017 Copyright © 2017 American Medical Association. All rights reserved
