Download Gene Expression - Pleasantville High School

Gene Expression
•Control
of Gene Expression
•Activation of a gene that results in the
formation of a _________.
•When transcription occurs a gene is
“__________” or “_______ ____”.
•Example: Gene for blue eyes is “expressed” only
in the iris of the eye.
•Genome: the complete genetic material
contained in an individual.
•Structural Genes: code for a particular
product.
Gene Expression Continued
Promoter: Segment of DNA that recognizes
RNA polymerase to promote transcription.
 Operator: Segment of DNA that can
________ _______________.
 Repressor Protein: ___________ a gene
from being expressed (“turns off the gene”)
 Regulator Gene: _________ the expression
of a specific gene by coding for a repressor.

Gene Expression and Development

Cell Differentiation: development of cells with
_______________ _____________.
◦ Controlled by __________ _________________.

Homeotic Genes are regulatory genes that
determine where anatomical structures will be
placed during development.

Cancer:
◦ Tumor: abnormal group of cells from
___________, abnormal cell division.
 Benign: no threat unless compressing a vital organ; in a
________ ______.
 Example: Fibroid cyst in uterus or breast, warts
Gene Expression and Development Cont.
 Malignant: abnormal cells __________ and
__________ healthy tissue elsewhere in the body.
 Metastasis: __________ of cancer beyond the
original site.

Kinds of Cancer
◦ Carcinoma: skin, __________ ___________ organs.
 Example: lung cancer, breast cancer
◦ Sarcomas: _______ and muscular tissue.
◦ Lymphomas: solid tumors in blood-forming tissue and
may cause ___________.
◦ Leukemia: uncontrolled production of _________
blood cells.
Causes of Cancer

Mutations: alter expression of genes.
◦ Spontaneous
◦ Caused by ___________ (substance that
increases the risk of cancer).
 Example: smoking, asbestos, radiation
◦ Viruses

Mutagen: agents that cause _________.