* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Let-7 is - University of Colorado-MCDB
Survey
Document related concepts
Designer baby wikipedia , lookup
Short interspersed nuclear elements (SINEs) wikipedia , lookup
Point mutation wikipedia , lookup
Long non-coding RNA wikipedia , lookup
Nucleic acid tertiary structure wikipedia , lookup
History of RNA biology wikipedia , lookup
Microevolution wikipedia , lookup
Polyadenylation wikipedia , lookup
Epigenetics of human development wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Mir-92 microRNA precursor family wikipedia , lookup
RNA silencing wikipedia , lookup
Messenger RNA wikipedia , lookup
RNA interference wikipedia , lookup
Non-coding RNA wikipedia , lookup
Primary transcript wikipedia , lookup
Transcript
Let-7 is A. a siRNA that inhibits transcription of its target gene B. a siRNA that inhibits translation of its target mRNA C. Likely a small RNA that inhibits translation of its target mRNA D. A small RNA that inhibits transcription of its target gene E. None of the above Let-7 was discovered A. By looking for interesting RNAs that might affect developmental timing in C. elegans. B. By genetic screens for mutations that affect developmental timing in C. elegans. C. By examining all the lethality genes that affect developmental timing in C. elegans D. By looking for lin-4-like small RNAs that affect developmental timing in C. elegans E. All of the above Let-7 likely acts by • A. Antagonzing the activity of lin-4 small RNA • B. inhibiting the translation of lin-41 • C. directly activating the translation of lin-29 • D. inhibiting the translation of lin-14 • E. none of the above From this paper, you learn that microRNA acts by A. binding to the target protein B. binding to the 3’ UTR of the target transcript C. binding to the promoter of the target gene D. binding to the intron of the target transcript E. Binding to the coding region of the target transcript