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SBI4U Molecular Genetics From Gene to Protein: Translation What needs to happen before the translation of genes into proteins can occur? “Talking Transcription”: Consider these new terms Codon Amino acid Anticodon Polypeptide Messenger RNA (mRNA) Ribosome Transfer RNA (tRNA) Large and small subunits Ribosomal RNA (rRNA) Initiation, elongation, termination Translation Notes: Initiation: Elongation: Ribosome – Reading Frame – Transfer RNA (tRNA) ‐ “A” site “P” site “E” site “Start” codon (AGU) “Stop” codon (UAA, UAG, UGA) 1 Elongation: Anticodons: Aminoacyl tRNA – Wobble Hypothesis ‐ The Steps: Termination: Modifications: 2
