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Nervous System Suzanne D'Anna 1 Nervous System master control system master communicating center  nerve tissue develops from embryonic ectoderm Suzanne D'Anna 2 Role of the Nervous System monitors changes - (sensory function)  processes and interprets information - (integrative)  elicits responses - (motor)  Suzanne D'Anna 3 Nervous System Organization anatomical organization - central nervous system (CNS) - peripheral nervous system (PNS)  functional organization - sensory - integrative - motor  Suzanne D'Anna 4 Central Nervous System (CNS) brain - cerebrum - diencephalon four principal parts - brain stem - cerebellum  spinal cord - continuation of brain stem - continues from base of skull to the 1st lumbar vertebra  Suzanne D'Anna 5 diencephalon cerebrum pituitary gland brain midbrain stem pons medulla oblongat Suzanne D'Anna a cerebellum spinal cord 6 Peripheral Nervous System (PNS) cranial nerves - 12 pairs - emerge from the brain  spinal nerves - 31 pairs - emerge from the spinal cord  Suzanne D'Anna 7 Functional Organization sensory - gathers information that occurs within internal and external environment  integrative - analyzes sensory information - decides necessary responses  motor - carries instructions (nerve impulses) to muscles and glands (effectors)  Suzanne D'Anna 8 Basic Types of Functional Neurons Suzanne D'Anna 9 Sensory Neurons  afferent neurons - carry information from various body parts to the brain or spinal cord (input) Motor Neurons  efferent neurons - carry instructions from the CNS to muscles and glands (output) Suzanne D'Anna 10 Interneurons or Connecting Neurons analyze information  determine appropriate response  located in the CNS  Suzanne D'Anna 11 Peripheral Nervous System (subdivisions) somatic nervous system (soma = body) - voluntary - sensations are consciously perceived  autonomic nervous system (auto = self) - involuntary and automatic - sensations are usually not consciously perceived  Suzanne D'Anna 12 Somatic Nervous System (SNS) sensory neurons - carry impulses to the CNS from receptors for general and special senses (touch, pressure, vibration, temperature, pain, proprioception, smell, taste, vision,hearing and equilibrium)  motor neurons - carry impulses away from CNS only to skeletal muscles  Suzanne D'Anna 13 Autonomic Nervous System (ANS) sensory neurons - carry impulses to the CNS from visceral receptors (internal organs)  motor neurons - carry impulses from CNS to smooth muscle, cardiac muscle, and glands  Suzanne D'Anna 14 Motor Division of Autonomic Nervous System Two principal divisions work together, i.e., impulses of one division activate an organ, while impulses from the other division inhibit the organ  sympathetic  parasympathetic Suzanne D'Anna 15 Sympathetic  prepares the body for energyexpending, stressful, or emergency situations Parasympathetic active under normal ordinary, restful conditions  counterbalances effects of sympathetic division  restores body to resting state  Suzanne D'Anna 16 Protection and Coverings of the Brain bones of cranium  cerebrospinal fluid  connective tissue membranes called meninges  vertebral column  Suzanne D'Anna 17 Cranium frontal  sphenoid  ethmoid  occipital  parietal  temporal  Suzanne D'Anna 18 Cerebrospinal Fluid (CSF) formed by filtration and secretion from networks of capillaries - choroid plexuses located in the (4) ventricles of the brain form blood-brain barrier  clear, colorless liquid  contains glucose, proteins, lactic acid, urea, cations, anions, and lymphocytes  Suzanne D'Anna 19 Cerebrospinal Fluid (cont.) acts as shock-absorbing medium  protects brain from banging against inner walls of cranium  is a medium for exchange of nutrients and waste products between blood and nervous tissue  Suzanne D'Anna 20 Cerebrospinal Fluid (cont.) significant changes in composition can indicate disease conditions - meningitis - tumors - multiple sclerosis  if drainage of CSF is obstructed, excessive pressure on the brain will cause hydrocephalus  Suzanne D'Anna 21 Blood-Brain Barrier permits certain substances to enter the fluid but prohibits others  protects the brain from harmful substances  formed by tightly adherent cell connections  Suzanne D'Anna 22 Meninges protective membranes  delicate  envelop brain and spinal cord  Three connective tissue membranes: - dura mater - arachnoid - pia mater  Suzanne D'Anna 23 Dura Mater outermost layer  leathery  next to bony inner surface of cranium  separated from arachnoid by subdural space which is fluid filled  Suzanne D'Anna 24 Arachnoid middle layer  looks like a cobweb  Two components: - layer next to the subdural space - system of supporting fibers (trabeculae) forming web-like structure between arachnoid and pia mater  Suzanne D'Anna 25 Arachnoid (cont.) in some areas, arachnoid material perforates dura mater forming protrusions called arachnoid villa  Functions: - reabsorption of CSF into blood  Suzanne D'Anna 26 Pia Mater innermost  thin layer of loose connective tissue  transparent  contains many blood vessels  between pia mater and nerve tissue is a thin layer of neuroglial processes firmly attached to pia mater  Suzanne D'Anna 27 Meningitis inflammation of meninges  serious threat to brain  bacterial and viral meningitis can spread to nervous tissue of CNS  Suzanne D'Anna 28 Regions of the Brain cerebrum (cerebral hemisphere )  diencephalon  brain stem  cerebellum  Suzanne D'Anna 29 Cerebrum (cerebral hemisphere) largest, obscures most of brain stem  looks like mushroom cap  made up of 2 deeply grooved hemispheres - left and right  Surface is covered by: - grooves - fissures or sulci - ridges - gyri or convolutions which serve as landmarks  Suzanne D'Anna 30 Cerebrum (con’t)  concerned with higher brain functions  Contains centers for: - interpreting sensory impulses - initiating voluntary muscular movements  stores information of memory  utilizes information in reasoning processes  functions in determining a person’s intelligence and personality Suzanne D'Anna 31 Left Hemisphere  More important for: - right-hand control - spoken and written language - numerical and scientific skills - reasoning Suzanne D'Anna 32 Right Hemisphere  More important for: - left-hand control - musical and artistic awareness - space and pattern perception - insight and imagination Suzanne D'Anna 33 Lobes each hemisphere is subdivided into 4 lobes  named for cranial bone that covers them  more precisely defined by surface landmarks, i.e., sulci and fissures  Suzanne D'Anna 34 Lobes (cont.) parietal lobe  occipital lobe  temporal lobe  frontal lobe  Suzanne D'Anna 35 White Matter underlying the cortex  whitish appearance is due to fatty component of myelin  consists of myelinated axons extending in three principal directions - association fibers - commissural fibers - projection fibers  Suzanne D'Anna 36 Association Fibers  connect and transmit impulses between gyri in the same hemispheres Suzanne D'Anna 37 Commissural Fibers  transmit impulses from the gyri in one cerebral hemisphere to corresponding gyri in the opposite hemisphere Suzanne D'Anna 38 Three Important Commissural Fibers corpus callosum (corpus = mass or body) - great commissure of the brain between the cerebral hemispheres  anterior commissure  posterior commissure  Suzanne D'Anna 39 Projection Fibers form descending and ascending tracts  tracts transmit impulses from cerebrum and other parts of brain to spinal cord  tracts transmit impulses from spinal cord to brain  Suzanne D'Anna 40 Gray Matter made primarily of densely packed neuron cell bodies  basal ganglia - paired masses of gray matter - found in cerebral hemispheres  cerebral cortex - layer of gray matter approx. 3 mm thick - has 6 distinct layers - divided into 3 areas based on function  Suzanne D'Anna 41 Cerebral Hemisphere  outer layer of gray matter is cerebral cortex - made up of lobes composed of dendrites and cell body neurons - interior is composed of white matter (nerve fibers arranged in bundles called tracts) Suzanne D'Anna 42 Functions of Cerebral Cortex  divided into three main areas based on function - sensory area - motor area - association area Suzanne D'Anna 43 Sensory Areas  Function in interpreting impulses, located in several lobes of cerebrum - general sensory area - primary visual area - primary auditory area - primary gustatory area - primary olfactory area Suzanne D'Anna 44 Sensory Areas primary gustatory primary auditory Suzanne D'Anna general sensory primary visual 45 General Sensory Area Receives impulses from: - the skin - muscles - internal organs  localizes precisely where sensations originate  located on the postcentral gryus on the occipital lobe  Suzanne D'Anna 46 Primary Visual Area receives input from the eyes  Interprets: - shape - color - movement  located on the occipital lobes  Suzanne D'Anna 47 Primary Auditory Area (cont.) receives input from internal ear (cochlea)  Interprets: - pitch - rhythm  located on the temporal lobes  Suzanne D'Anna 48 Primary Gustatory Area receives input from taste buds  Interprets: - sensations related to taste (sweet, sour, salty, bitter)  located at base of postcentral gryus on parietal lobes  Suzanne D'Anna 49 Primary Olfactory Area receives input from olfactory bulbs  Interprets: - sensations related to smell  located on temporal lobes  Suzanne D'Anna 50 Motor Areas All located on frontal lobes, control actions of specific muscles or groups of muscles - primary motor area - motor speech area Suzanne D'Anna 51 Motor Areas primary motor motor speech (Broca’s) Suzanne D'Anna 52 Primary Motor Area controls muscles in specific parts of body  located on precentral gyrus of frontal lobe  The translation of thoughts into speech involves the motor speech area  Suzanne D'Anna 53 Motor Speech Area (Broca’s Area) Coordinates complex muscular actions of the: - mouth - tongue - larynx  located at junction of temporal, parietal, and occipital lobes in only one cerebral hemisphere (usually left)  Suzanne D'Anna 54 Association Areas  Concerned with: - personality - intelligence - emotions - reasoning - problem solving - creativity judgment Suzanne D'Anna 55 Association Areas (cont.) somatosensory association area  visual association area  auditory associations area (Wernick’s area)  gnostic area  premotor area  frontal eye field  Suzanne D'Anna 56 Association Areas promotor somatosensory gnostic visual frontal eye field Suzanne D'Anna auditory 57 Somatosensory Association Area integrates and interprets sensations  Determines: - shape and texture of an object - orientation of one object to another as they are felt - sense relation of one body part to another  stores memories, so present sensations can be compared to previous experiences  Suzanne D'Anna 58 Visual Association Area relates present to past visual experiences by recognizing and evaluating what is seen  located in occipital lobe  Suzanne D'Anna 59 Auditory Associations Area (Wernick’s area) interprets meaning of speech  determines type of sound - speech, music, and noise  also interprets meaning of speech by translating words into thoughts  located inferior to primary auditory area in temporal lobe  Suzanne D'Anna 60 Gnostic Area (gnosis = knowledge)  (NOS-tik) integrates sensory interpretations from the association areas and impulses from other areas so that a common thought can be formed - sends signals to other parts of the brain to cause appropriate response Suzanne D'Anna 61 Premotor Area anterior to primary motor area  neurons from this area communicate with primary motor cortex, sensory associations areas in the parietal lobe, the basal ganglia, and the thalamus  concerned with learned motor activities of complex and sequential nature such as writing or playing the piano  Suzanne D'Anna 62 Frontal Eye Field in frontal cortex  controls voluntary scanning movements of the eyes such as searching for a word on a page of text or dictionary  Suzanne D'Anna 63 Diencephalon consists primarily of the thalamus and the hypothalamus  sits on top of brain stem  Suzanne D'Anna 64 Thalamus oval structure  consists of paired masses of gray matter (1 inch long) organized into nuclei  form lateral walls of third ventricle  right and left halves are joined by bridge of gray matter called intermediate mass  principal relay station  allows crude recognition of sensations; pain, temperature, or pressure  Suzanne D'Anna 65 Hypothalamus under thalamus  single most important region of brain for maintaining homeostasis  Regulates: - temperature, hunger, thirst, smell, fear, rage, sexual behavior, endocrine rhythms, and posterior and anterior pituitary secretions  Suzanne D'Anna 66 Brain Stem Three parts: - midbrain - pons - medulla oblongata  three inches long  Suzanne D'Anna 67 Midbrain mesencephalon (meso = middle, enkephalos = brain)  extends from pons to diencephalon  about one inch  involved with visual and auditory stimuli  Suzanne D'Anna 68 Pons (pons = bridge) directly above medulla  anterior to cerebellum  about one inch long  consists of white matter with regions of gray matter (nuclei) scattered throughout  bridge connecting spinal cord with brain via transverse and longitudinal fibers  helps to control respiration  Suzanne D'Anna 69 Medulla Oblongata merges with spinal cord  contains all ascending and descending tracts that connect spinal cord and various parts of brain  contains centers that control heart rate, blood pressure, breathing, swallowing and vomiting  Suzanne D'Anna 70 Cerebellum looks like a cauliflower  located behind the pons and below occipital lobes of cerebrum  controls subconscious skeletal muscle contractions required for smooth, coordinated movements and equilibrium “automatic pilot”  second largest part of brain  Suzanne D'Anna 71 Spinal Cord continuation of brain stem  extends from large opening in base of cranium (foramen magnum) down to upper region of the lower back (1st lumbar vertebra)  cylindrically shaped  approximately 17 inches long  1 inch in diameter  Suzanne D'Anna 72 Spinal Cord (cont.) Surrounded and protected by: - meninges - cerebrospinal fluid - a layer of fatty tissue - the vertebra  no possibility of spinal cord injury below L4; ideal site for removal of cerebral spinal fluid  Suzanne D'Anna 73