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Biology HS/Science Unit: 08 Lesson: 02 Mendel's Law of Segregation Mendel's hypothesis has four essential parts: 1. “Alternative versions of genes account for variations in inherited characters.” This is the concept of alleles. Alleles are different versions of genes that control the same trait. For example, each pea plant has two genes that control seed color. There are also two possible colors (green or yellow), so there are two different genes for seed color. 2. “For each character trait (such as height, color, texture etc.), an organism inherits two genes, one from each parent.” This statement indirectly refers to the fact that when somatic cells (any cell of a living organism other than the reproductive cells) are produced from two gametes, one allele comes from the mother and one from the father. These alleles could be the same (true-breeding organisms/self-pollination) or different (hybrids/cross-pollination). 3. “If the two alleles differ, then one, the dominant allele, is fully expressed in the organism's appearance; the other, the recessive allele, has no noticeable effect on the organism's appearance.” ©2012, TESCCC 11/05/12 page 1 of 2 Biology HS/Science Unit: 08 Lesson: 02 4. “The two genes for each character segregate during gamete production.” This references meiosis, when the chromosome number changes from diploid to haploid (for example, in humans from 46 to 23). The genes are sorted into separate gametes, resulting in variation. “This sorting process depends on genetic “recombination”. During this time, genes mix and match in a random and yet very specific way. Genes for each trait only trade with genes of the same trait on the opposing strand of DNA so that all the traits are covered in the resulting offspring. For example, color genes do not trade off with genes for texture.” It was very important that Mendel observed inheritable traits that do not have intermediate forms because that was the leading biological theory during his time. This theory stated that inherited traits blended from generation to generation. (There are exceptions to this general rule. Some genes are now known to have incomplete dominance. In this situation, the dominant gene has incomplete expression in the resulting phenotype creating a “mixed” phenotype.) Law of Independent Assortment According to the principle* of independent assortment, different pairs of alleles are passed to offspring independently of each other. The result is that new combinations of genes present in neither parent are possible. For example, a pea plant's inheritance of the ability to grow tall instead of short does not make it more likely that it will also inherit the ability to produce purple flowers instead of white flowers. Likewise, the principle of independent assortment explains why the human inheritance of a particular eye color does not increase or decrease the likelihood of having six fingers on each hand. Today, we know this is due to the fact that the genes for independently assorted traits are located on different chromosomes. *Some biologists call Mendel’s theories “laws” and some call them “principles”. Information adapted from: http://naturalselection.0catch.com/Files/gregormendel.html ©2012, TESCCC 11/05/12 page 2 of 2