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Reliability
in genetics
Products catalogue
Kits for clinical genetic testing
Global sales
Reliability
in genetics
Imegen is a leading designer and manufacturer of kits for clinical
genetic testing based on a wide range of molecular technologies.
Our portfolio currently includes more than 100 references for kits
based on Sanger and NGS sequencing technologies, digital PCR, and
real time PCR.
Since 1998, we have developed the highest quality products to
provide pioneering solutions for the clinical doctors worldwide.
We improve and adapt our service to your needs.
EUROPE
Belgium
Bulgaria
Denmark
Greece
Iceland
Ireland
Italy
Netherlands
Portugal
Spain
Turkey
UK
ASIA
Saudi Arabia
Iran
India
Malaysia
Philippines
AFRICA
Morocco
LATIN AMERICA
Mexico
Colombia
Argentina
Chile
Peru
Bolivia
NORTH AMERICA
USA
Worldwide technical support
ISO 9001
Imegen is certified for the design,
development, manufacturing and
commercialization of kits for
genetic testing.
ISO 13485
Imegen is certified for the design,
development, manufacturing and
commercialization of kits for in
vitro diagnosis.
Visit www.imegen.es or contact us for further
information on our kits:
Phone: +34 963 212 340
e-Mail: [email protected]
imegenTM is a trademark of Instituto de Medicina
Genómica, registered as imegen® in Spain
Available Technologies
Imegen strives for optimal diagnostic efficacy by using cutting-edge molecular and genetic analysis
technologies and by selecting the most appropriate method for each clinical case
imegenTM kits | User-friendly | Easy interpretation of Results
(Complete Sequencing by NGS)
NextGeneDx
FLEXIBLE
CAN BE RUN ON
COMMON PCR
INSTRUMENTS
COMPLETE
CONTAINS ALL
NECESSARY
COMPONENTS.
NO EXTRA COST
Reference
Kit description
Kit name
rnx
Speciality
IMG-172
Molecular genetic analysis of BRCA1 and BRCA2 genes by NGS
imegenTM-BRCA-NGS
12
Oncology; Andrology,
gynecology and obstetrics
IMG-190
Molecular genetic analysis of PTPN11, RAF1, SOS1, KRAS and
BRAF genes by NGS
imegenTM-Noonan-NGS
6
Paediatrics; Andrology,
gynecology and obstetrics
IMG-191
Molecular genetic analysis of PTPN11, RAF1, SOS1, KRAS, NRAS, SPRED1, HRAS,
MAP2K1, BRAF, MAP2K2, CBL, SHOC2 and RIT1 genes related to rasopathy by NGS
imegenTM-Noonan-Like-NGS
10
Paediatrics; Andrology,
gynecology and obstetrics
IMG-192
Molecular genetic analysis of FBN1, TGFBR1 and TGFBR2 genes
by NGS
imegenTM-Marfan-NGS
6
Cardiology; Paediatrics
IMG-227
Molecular genetic analysis of CFTR, PRSS1, SPINK1, CTRC and
CASR genes related to pancreatitis by NGS
imegenTM- Pancreatitis-NGS
6
Digestive
IMG-234
Plasmids to track samples along for the NGS sequencing genetic
analysis
imegenTM-Sample tracking Kit
48x12
IMG-259
Molecular genetic analysis of SCN5A, KCNQ1, KCNH2, KCNE1,
KCNE2 and CAV3 genes by NGS
imegenTM-QT Largo-NGS
6
Cardiology
IMG-260
Molecular genetic analysis of PKP2, DSP, DSG2, DSC2 and JUP
genes by NGS
imegenTM-ARVD–NGS
6
Cardiology
IMG-261
Molecular genetic analysis of ACTC1, MYBPC3, MYH6, MYH7, MYL2,
MYL3, TCAP, TNNC1, TNNI3, TNNT2 and TPM1 genes by NGS
imegenTM-Miocardiopatía
Hipertrófica-NGS
6
Cardiology
NGS based on Illumina technology.
VALIDATED
CE/ IVD
MARKED
Techniques and features
NextGeneDx
Liquid format
Capillary Electrophoresis
Reference
Kit description
Kit name
rnx
Speciality
IMG-117-2
Molecular genetic analysis of BRCA1 gene by Sanger sequencing
TM
imegen -BRCA1
12
Oncology; Andrology,
gynecology and obstetrics
IMG-118-2
Molecular genetic analysis of BRCA2 gene by Sanger sequencing
imegenTM-BRCA2
12
Oncology; Andrology,
gynecology and obstetrics
IMG-132
Molecular genetic analysis of MSH2 gene by Sanger sequencing
imegenTM-MSH2
6
Oncology; Digestive
IMG-133
Molecular genetic analysis of MLH1 gene by Sanger sequencing
imegenTM-MLH1
6
Oncology; Digestive
IMG-134
Molecular genetic analysis of MSH6 gene by Sanger sequencing
imegenTM-MSH6
6
Oncology; Digestive
IMG-135
Molecular genetic analysis of CFTR gene by Sanger sequencing
imegenTM-CFTR
12
Paediatrics; Andrology,
gynecology and obstetrics
IMG-148
Molecular genetic analysis of APC gene by Sanger sequencing
imegenTM-APC
6
Oncology
IMG-150
Molecular genetic analysis of SCN1A gene by Sanger sequencing
imegenTM-SCN1A
6
Paediatrics; Neurology
IMG-152
Detection of SCA1, SCA2, SCA3, SCA6 and SCA7 expansions by
fragment analysis
imegenTM-SCAs
12
Neurology
IMG-153
Detection of CAG expansion in the AR gene by fragment analysis
imegenTM-SBMA
12
Paediatrics; Neurology
IMG-154
Detection of CAG expansion in the HTT gene by fragment analysis
imegenTM-Huntington
12
Neurology
IMG-155
Detection of GAA expansion in the FXN gene by fragment analysis
imegenTM-Friedreich
12
Paediatrics; Neurology
IMG-156
Molecular genetic analysis of HBB gene by Sanger sequencing
imegenTM-HBB
24
Haematology
IMG-173
Detection of CTG expansion in the DMPK gene by fragment
analysis
imegenTM-DM1
12
Neurology
IMG-178
Molecular genetic analysis of NF1 gene by Sanger sequencing
imegenTM-NF1
6
Oncology ; Paediatrics
IMG-237
Detection of INDEL type mutations in CALR gene by fragment
analysis
imegenTM-CALR kit
33
Oncology; Haematology
IMG-238
Detection of ITD mutations in FLT3 gene by fragment analysis
imegenTM-FLT3 kit
33
Oncology; Haematology
Techniques and features
Capillary Electrophoresis
Liquid format
Real Time PCR
Reference
Kit description
Kit name
rnx
Speciality
IMG-108
t(9;22)(q34;q11) BCR-ABL rearrangement detection by real time
PCR
imegen -BCR-ABL
48X2
Oncology; Haematology
IMG-109
CBFB-MYH11 inv(16)(p13q22) A typeA rearrangement
quantification by real time PCR
imegenTM-Inv16
48X2
Oncology; Haematology
IMG-110
Genotyping of JAK2 p.V617F mutation by real time PCR
imegenTM-JAK2
50
Oncology; Haematology
IMG-111
PML-RARa t(15;17)(q22;q21) rearrangement quantification by
real time PCR
imegenTM-PML-RARA
48X2
Oncology; Haematology
IMG-116-1
Screening of informative markers by real time PCR
imegenTM-Quimera Screening I
6X8
Oncology; Haematology
IMG-116-2
Quantification of SRY in hematopoietic chimeras by real time PCR
imegenTM-Quimera SRY
25X2
Oncology; Haematology
IMG-116-3
Quantification of Q116-3I in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-3I
25X2
Oncology; Haematology
IMG-116-4
Quantification of Q116-4I in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-4I
25X2
Oncology; Haematology
IMG-116-5
Quantification of Q116-5I in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-5I
25X2
Oncology; Haematology
IMG-116-6
Quantification of Q116-6I in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-6I
25X2
Oncology; Haematology
IMG-116-7
Quantification of Q116-7I in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-7I
25X2
Oncology; Haematology
IMG-116-8
Quantification of Q116-8I in hematopoietic chimeras by real time PCR
imegenTM-Quimera Q116-8I
25X2
Oncology; Haematology
IMG-116-9
Quantification of Q116-9I in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-9I
25X2
Oncology; Haematology
IMG-116-10
Quantification of Q116-10I in hematopoietic chimeras by real
time PCR
imegenTM-Quimera Q116-10I
25X2
Oncology; Haematology
IMG-116-11
Quantification of Q116-11I in hematopoietic chimeras by real
time PCR
imegenTM-Quimera Q116-11I
25X2
Oncology; Haematology
IMG-116-12
Quantification of Q116-12I in hematopoietic chimeras by real
time PCR
imegenTM-Quimera Q116-12I
25X2
Oncology; Haematology
IMG-116-13
Quantification of Q116-4D in hematopoietic chimeras by real time
PCR
imegen-Quimera Q116-4D
25X2
Oncology; Haematology
IMG-116-14
Quantification of Q116-5D in hematopoietic chimeras by real time
PCR
imegenTM-Quimera Q116-5D
25X2
Oncology; Haematology
IMG-116-17
Quantification of Q116-10D in hematopoietic chimeras by real
time PCR
imegenTM-Quimera Q116-10D
25X2
Oncology; Haematology
IMG-116-18
Quantification of RhD in hematopoietic chimeras by real time PCR
imegenTM-Quimera RhD
25X2
Oncology; Haematology
IMG-116-20
Quantification of Q116-20I in hematopoietic chimeras by real
time PCR
imegenTM-Quimera Q116-20I
25X2
Oncology; Haematology
Can be used in a wide variety of thermal cyclers.
TM
Techniques and features
Real Time PCR
Dry format
Real Time PCR
Reference
Kit description
Kit name
rnx
Speciality
IMG-116-21
Quantification of Q116-12D in hematopoietic chimeras by real
time PCR
imegen -Quimera Q116-12D
25X2
Oncology; Haematology
IMG-116-22
Screening of informative markers by real time PCR
imegenTM-Quimera Screening II
6X8
Oncology; Haematology
IMG-116-23
Quantification of Q116-23I in hematopoietic chimeras by real time PCR
imegenTM-Quimera Q116-23I
25X2
Oncology; Haematology
IMG-116-24
Screening of informative markers by real time Multiplex PCR
imegenTM-QScreening
Multiplex I
10X8
Oncology; Haematology
IMG-116-26
Screening of informative markers by real time Multiplex PCR focus
on digital PCR
imegenTM-Quimera Screening
Multiplex Plus
10X8
Oncology; Haematology
IMG-121
M-BCR rearrangement quantification ( p210 BCR-ABL) by real
time PCR
imegenTM-M-BCR-ABL
48X2
Oncology; Haematology
IMG-122
m-BCR rearrangement quantification ( p190 BCR-ABL) by real
time PCR
imegenTM-m-BCR-ABL
48X2
Oncology; Haematology
IMG-127
Detection of A(TA)7TAA allele in the UGT1A1 gene promotor by real
time PCR
imegenTM-Gilbert
48
Digestive; Paediatrics
IMG-130
PML-RARa t(15;17)(q22;q21) rearrangement detection by real
time PCR
imegenTM-PML-RARA Screening
48X2
Oncology; Haematology
IMG-199
Genotyping of p.(Ala368Ser) mutation of SERPINC1 (antithrombin)
by real time PCR
imegenTM-Cambridge II
48
Haematology
IMG-211
Genotyping of Glu342Lys (PI-Z allele) and Glu264Val (PI-S allele)
mutations of SERPINA1 geneby real time PCR
imegenTM-Alfa-1-AT
48X2
Paediatrics; Digestive
IMG-212
Genotyping of c.677C>T mutation of MTHFR gene by real time PCR
imegenTM-MTHFR
48
Haematology; Andrology,
gynecology and obstetrics
IMG-213
Genotyping of rs1297980 polymorphism of IL28B gene by real
time PCR
imegenTM-IL28B
48
Digestive
IMG-214
Genotyping of c.20110G>A mutation of F2 (prothrombin) gene by
real time
imegenTM-Factor II
48
Haematology; Andrology,
gynecology and obstetrics
IMG-215
Genotyping of c.46C>T mutation of F12 gene by real time PCR
imegenTM-Factor XII
48
Haematology; Andrology,
gynecology and obstetrics
IMG-216
Genotyping of c.1298A>C mutation of MTHFR gene by real time
PCR
imegenTM-MTHFR II
48
Haematology; Andrology,
gynecology and obstetrics
IMG-217
Genotyping of p.Arg506Gln mutation of F5 (Leiden) gene by real
time PCR
imegenTM-Factor V
48
Haematology; Andrology,
gynecology and obstetrics
IMG-218
Genotyping of p.Cys282Tyr, p.His63Asp.1298A>C and p.Ser65Cys
mutations of HFE gene by real time PCR
imegenTM-HFE
48X3
Haematology
IMG-220
Genotyping of p.Cys112Arg and p.Arg158Cys variants of APOE
gene by real time PCR
imegenTM-Apoe
48X2
Neurology
IMG-235
Detection of A, B and D-type mutations of NPM1 gene by real time
PCR
imegenTM-NPM1 kit
24
Oncology; Haematology
IMG-236
Detection of W515L and W515K mutations of MPL gene by real
time PCRl
imegenTM-MPL kit
24
Oncology; Haematology
Can be used in a wide variety of thermal cyclers.
TM
Techniques and features
Real Time PCR
Liquid Format
Dry format
Digital PCR
Reference
Kit description
Kit name
rnx
Speciality
IMG-116-27
Quantification of SRY in hematopoietic chimeras by digital PCR
imegen -Quimera SRY dPCR
12
Oncology; Haematology
IMG-116-28
Quantification of RhD in hematopoietic chimeras by digital PCR
imegenTM-Quimera RhD dPCR
12
Oncology; Haematology
IMG-116-29
Quantification of Q116-3I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-3I
dPCR
12
Oncology; Haematology
IMG-116-30
Quantification of Q116-4I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-4I
dPCR
12
Oncology; Haematology
IMG-116-31
Quantification of Q116-5I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-5I
dPCR
12
Oncology; Haematology
IMG-116-32
Quantification of Q116-6I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-6I
dPCR
12
Oncology; Haematology
IMG-116-33
Quantification of Q116-7I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-7I
dPCR
12
Oncology; Haematology
IMG-116-34
Quantification of Q116-11I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-11I
dPCR
12
Oncology; Haematology
IMG-116-35
Quantification of Q116-10I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-10I
dPCR
12
Oncology; Haematology
IMG-116-36
Quantification of Q116-12D in hematopoietic chimeras by digital
imegenTM-Quimera Q116-12D
dPCRdPCR
12
Oncology; Haematology
IMG-116-37
Quantification of Q116-23I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-23I
dPCR
12
Oncology; Haematology
IMG-116-38
Quantification of Q116-24I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-24I
dPCR
12
Oncology; Haematology
IMG-116-39
Quantification of Q116-25I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-25l
dPCR
12
Oncology; Haematology
IMG-116-40
Quantification of Q116-26D in hematopoietic chimeras by digital
imegenTM-Quimera Q116-26D
dPCR
12
Oncology; Haematology
IMG-116-41
Quantification of Q116-27D in hematopoietic chimeras by digital
imegenTM-Quimera Q116-27D
dPCR
12
Oncology; Haematology
IMG-116-42
Quantification of Q116-28I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-28I
dPCR
12
Oncology; Haematology
IMG-116-43
Quantification of Q116-29D in hematopoietic chimeras by digital
imegenTM-Quimera Q116-29D
dPCR
12
Oncology; Haematology
IMG-116-44
Quantification of Q116-30D in hematopoietic chimeras by digital
imegenTM-Quimera Q116-30D
dPCR
12
Oncology; Haematology
IMG-116-45
Quantification of Q116-31I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-31I
dPCR
12
Oncology; Haematology
IMG-116-46
Quantification of Q116-32I in hematopoietic chimeras by digital
imegenTM-Quimera Q116-32I
dPCR
12
Oncology; Haematology
IMG-116-47
Quantification of Q116-33I in hematopoietic chimeras by digital
imegen-Quimera Q116-33l
dPCR
12
Oncology; Haematology
IMG-116-48
Quantification of Q116-34D in hematopoietic chimeras by digital
imegenTM-Quimera Q116-34D
dPCR
12
Oncology; Haematology
For ThermoFisher and Bio-Rad platforms.
TM
Techniques and features
Digital PCR
Liquid format
Dry format
NextGeneDx
(complete sequencing by NGS)
As experts in human genetic testing, with more than 25 years of
experience, we have developed NextGeneDx®, a new NGS-based
technology designed to obtain the complete and specific DNA
sequence of a simultaneous number of genes involved in inherited
diseases.
NextGeneDx® kits are ready to use in combination with Sample
tracking kit (REF: IMG-234), allowing each sample to be easily
monitored from the PCR reactions preparation step to bioinformatics
analysis avoiding sample-crossing throughout the protocol.
The main advantages of NextGeneDx® kits are:
COMPLEMENTS: SOFTWARE + SAMPLE TRACKING
Design adapted to concrete clinical matters, reducing diagnostic
uncertainty, and therefore, increasing its clinical value.
High resolution and coverage (> 100X) of all coding regions of the
involved exons and adjacent intronic regions (> 10 bp).
Specificity and robustness comparable to Sanger together with
superior sensitivity, since this tool can detect mosaicisms.
Very usefull to obtain quality acreditations and certifications.
Reference
Kit description
Kit name
IMG-234
Plasmids to track samples along for the NGS
sequencing genetic analysis
imegen -Sample
tracking Kit
TM
rxn
48X12
Capillary electrophoresis
Detection of large pathogenic expansions
Pathogenic expansions are mainly caused by an increase in the number
of repetitions of trinucleotides (CAG, CTG, CGG, GAA,…), although there
are also expansions caused by internal tandem duplications (ITDs) or
variations due to insertions/deletions changes.
More than 373 genes analyzed by this technology.
Our kits for fragment analysis by the capillary electrophoresis technique
are aimed at identifying and/or quantifying the number of repetitions
that can be considered to be normal in the population and identifying
when the number of repetitions exceeds this threshold value.
Reliability
in genetics
Digital PCR
Digital PCR provides ultrasensitive and absolute DNA
quantification. It is paticulary useful for low abundance
targets and for monitoring subtle changes in target
levels that cannot be detected with real-time PCR.
App imegen Quimera
Advantages: No standard curves, no sample
replicates, and no pre-transplant samples to
quantify the informative marker.
Our Quimera kits include a useful App to help
medical doctors to monitor their patients.
Real Time PCR
Real time PCR can be used in a wide range of applications. This
versatile technology enables sensitive and specific target detection.
TaqMan technology based kits
The most common method for labelling and detecting qPCR products
Advantages:
Results in 3 hours
Easy interpretation of Results
Reliability
in genetics
Reliability
in genetics
C/ Agustín Escardino 9,
Parc Científic de la Universitat de València
46980 Paterna · Valencia • SPAIN
[email protected]
www.imegen.es