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Neural basis for memory Multiple choice questions 1. According to Kandel, in which part of a neuron are memories formed? A. In the dendrite B. In the synapse C. In the axon D. In the myelin sheath 2. Damage to the hippocampus may result in: A. Difficulty forming memories B. Difficulty speaking C. Difficulty walking D. Difficulty breathing 3. Lacey fell and received a nasty head injury. When she awoke from her concussion, she could not remember the last five years. She most likely has: A. Anterograde amnesia B. Retrograde amnesia C. Proactive amnesia D. Retroactive amnesia 4. Which of the following causes of forgetting is a result of degeneration of neurons in the hippocampus? A. Retrograde amnesia B. Anterograde amnesia C. Alzheimer’s disease D. Dementia 5. In what part of the brain does memory consolidation take place? A. The reticular formation B. The cerebral cortex C. The hippocampus D. The corpus callosum Questions 6 and 7 refer to the following information. In the movie ’50 First Dates’, Drew Barrymore’s character wakes up every day with no memory of the day before. Her memory of events that occurred before the car accident is perfectly intact, but since the accident she is unable to form new memories. She has a memory that she builds on for the whole day when she is awake, but when she falls asleep these memories are lost. 6. Drew Barrymore’s character is most likely suffering from: A. Anterograde amnesia B. Retrograde amnesia C. Proactive amnesia D. Retroactive amnesia 1 7. One inconsistency with the movie character’s condition and that of real-life sufferers of this type of amnesia is that: A. Usually women do not experience amnesia B. Real-life sufferers will learn to form new memories within a year C. Real-life sufferers cannot retain new memories for a whole day D. Real-life sufferers usually forget the events before the accident as well Questions 8 and 9 relate to the following scenario. In one piece of research into memory, Hudspeth and his colleagues administered electroconvulsive shock therapy (ECT) to rats to see the effect it would have on their memory. After rats had learned to navigate a maze they were administered shocks at differing intervals: Group A received the shock immediately after learning the maze, Group B 20 seconds after learning the maze, Group C 30 minutes after learning the maze and Group D 60 minutes after learning the maze. The researchers then measured how many errors the rats made when navigating the maze, to measure their retention rates. 8. Hudspeth and his colleagues helped to provide evidence for which theory? A. Consolidation theory B. Semantic network theory C. Retrieval failure theory D. Motivated forgetting 9. The results of the study into the effect of ECT on the memory of rats showed that: A. Groups A, B and C had no recollection of the maze B. Groups A and B experienced more errors than groups C and D C. Group D experienced fewer errors than the other three groups D. Group B experienced a better retention rate than group C Short answer questions 1. Callum is out playing football one afternoon for his football club, the Devils. Halfway through the first quarter, Callum falls from taking a mark and lands directly on his head. His parents are worried about him and take him to the local hospital. The doctor asks Callum what happened but Callum says he can’t remember any of the football game at all. a) Which theory explains why Callum is unable to remember the football game? __________________________________________________________________________________ b) According to this theory, why is Callum unable to remember the game? __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 2 c) Callum and his family live about an hour away from the football ground. Is Callum likely to remember leaving home before the game? Explain your answer. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 1 + 1 + 2 = 4 marks 2. Provide two symptoms of Alzheimer’s disease. __________________________________________________________________________________ __________________________________________________________________________________ 2 marks 3. With reference to the type of memory that is affected, explain what happens to the memory of a patient suffering from anterograde amnesia. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 2 marks 4. Explain the difference between Alzheimer’s disease and dementia. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 2 marks 5. Explain the role of the neuron in terms of memory formation. __________________________________________________________________________________ __________________________________________________________________________________ 1 mark 6. Distinguish between the two types of amnesia. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 2 marks 3 Solutions Multiple choice 1.B 2.A 3.B 4.C 5.C 6.A 7.C 8.A 9.B Short answer questions 1a) Consolidation theory b) Consolidation theory states that a physical change occurs in the brain when a memory trace is formed. This takes around 30 minutes and if the process is interrupted the memory may never be consolidated. c) Yes, only memories 30 minutes prior to the accident will be lost. 2. Alzheimer’s disease is characterised by memory loss and personality changes 3. In anterograde amnesia, new long-term memories are unable to be formed. This means that the patient has difficulty in encoding memories from short-term to long-term memory. 4. Dementia is a symptom resulting in a deterioration of cognitive abilities. Alzheimer’s may be the cause of this symptom. 5. The formation of memories is a result of a physical change in the brain that occurs in the synapses of neurons. 6. Anterograde amnesia is an organic cause of forgetting that involves sufferers being unable to form new memories after an accident has occurred. Retrograde amnesia is an organic cause of forgetting that is characterised by the inability to retrieve memories that have been stored in long-term memory before an accident has occurred. 4