Download Unit Overview AP Biology E01: Biochemistry and Introduction to Cells

Unit Overview
AP Biology E01: Biochemistry and Introduction to Cells
This unit serves as an introduction and a review of the basic biochemistry principles of atoms, molecules, bonding, pH,
water, organic functional groups, and enzymes. Students will also trace the development of cell theory, distinguish
between the two basic cell types, identify sub-cellular structures and their functions, and determine the significance of
how cells move material across cell membranes, metabolism and enzymes.
Students are expected to complete the reading in the digital textbook, watch the online lessons, complete the 6
virtual labs, prepare and peer review 1 lab report, participate in the discussion forum, complete the glossary entries,
answer 6 free response questions and take 2 unit tests.
Big Ideas (Outcomes)
1. The Student Will define atoms, isotopes, molecules, and bonding (ionic, covalent, and hydrogen).
2. TSW be able to relate the use of isotopes in the context of saving lives today as well as research another use
of isotope for environmental and/or social concerns.
3. TSW analyze the importance of the polarity of the water molecule with relationship to homeostasis,
cohesion, and solvent properties.
4. TSW describe the acid/base nature of a substance, given its pH.
5. TSW identify organic functional groups.
6. TSW describe the source, composition, synthesis and catalysis of carbohydrates, lipids, proteins and nucleic
acids in the cell.
7. TSW differentiate between prokaryotic and eukaryotic cells.
8. TSW differentiate between plant and animal cells.
9. TSW describe the structure and functions of the gram positive and gram negative cell membrane.
10. TSW explain the similarities and differences between active and passive transport and the mechanisms of
transport including diffusion, osmosis, active transport and phagocytosis.
11. TSW measure water potential of a solution and determine the osmotic concentration of living tissue relating
it to isotonic, hypertonic, and hypotonic solutions.
12. TSW identify and describe the structure and function of organelles present in the cell.
13. TSW describe methods of cell motility and microstructure of related organelles.
14. TSW explain how chemical reactions relate to free energy changes and equilibrium.
15. TSW explain how energy, metabolic pathways, and reactions are generally related.
16. TSW describe the structure and function of common enzymes.
17. TSW describe the relationships between enzymes, coenzymes and cofactors.
18. TSW describe how enzyme activity is regulated by homeostatic mechanisms and how specific factors (pH,
temperature, enzyme concentration, substrate concentration) affect enzyme activity rates.
Unit Outline and Timetable
Duration
Dates
Topics
Sections
Atoms, Isotopes,
Molecules, and
Bonding
2.1, 2.3
Water and It's
Properties
2.4
Lessons
Labs
Lesson 1
E01 Lab
Activity 1:
Solubility
Activities
Test
Discussion
Forum,
Glossary, Free
Response
Questions, Lab
Reports, and
Self
Assessments
E01 Unit
Tests (2)
E01 Lab
Activity 2:
Acid - Base
Titration
Organic Molecules
2 Weeks
Oct 8 28
Prokaryotic vs.
Eukaryotic
Sub-cellular
organization
Membranes
2.2
Lessons
2, 3, 4
3.1
Lesson 5
3.2
3.3
Lessons
6, 7
E01 Lab
Activity 3:
Capillarity
E01 Lab
Activity 4:
Osmosis
E01 Lab
Activity 5:
Membrane
Diffusion
Chemical Reactions
and Metabolic
Pathways
Lesson 8
Enzymes and their
Importance
Lesson
9, 10
E01 Lab
Activity 6:
Enzymes
Resources
•
Video Lessons
o Lesson 1: Why is water important to Biology?
o Lesson 2: Intro to Organic Molecules – Functional Groups
o Lesson 3: Biomolecules Part 1: Intro, Carbohydrates and Lipids
o Lesson 4: Biomolecules Part 2: Nucleic Acids and Proteins
o Lesson 5: Tour Through a Eukaryotic Cell
o Lesson 6: Structure and Function of the Cell Membrane
o Lesson 7: Tonicity – Relative Solute Concentrations
o Lesson 8: Introduction to Metabolism
o Lesson 9: How Enzymes Work – Metabolism Part 2
o Lesson 10: ATP the Cellular Currency – Metabolism Part 3
Formative Assessments
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Self Assessments (1 per lesson with immediate explanatory feedback, unlimited number of attempts)
Glossary Study Guide (major questions to be answered here)
Learning Discussion Forum
6 Online Virtual Labs
Summative Assessments
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2 Multiple-choice Unit Exam (Moodle Scored)
6 Free Response Questions
1 Lab Report (Peer Reviewed)
Major Questions
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What three subatomic particles make up atoms and what are their properties?
How are all isotopes of an element similar?
In what ways do molecules differ from their component elements?
What are they main types of chemical bonds?
How does the unique structure of water contribute to its unique properties?
How does water's polarity influence its properties as a solvent?
Why is it important for cells to buffer solutions against rapid changes in pH?
What are the functions of each of the four groups of macromolecules?
How is a molecule's biological function related to its shape?
How do energy changes affect whether a chemical reaction will occur?
What role do enzymes play in living things and what affects their function?
What is the cell theory?
How are prokaryotic and eukaryotic cells different?
What is the structure and function of the cell nucleus?
What are the functions of vacuoles, lysosomes, and the cytoskeleton?
What organelles help make and transport proteins?
What are the function of chloroplasts and mitochondria?
What is the function of the cell membrane?
What is passive transport?
What is active transport?
How do individual cells maintain homeostasis?
How do the cells of multi-cellular organisms work together to maintain homeostasis?