Download supp-MBS 103-B

Supplementary MBBS I (First) Professional
Examination 2015-16
Course Code: MBS103
Paper ID: S322242
Biochemistry -II
Time: 2 Hours 40 Minutes
Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support
your answer.
Part ‘B’
1.
What is homeostasis? Discuss regulation of acid-base
balance in human body.
(10)
2.
Define mineral metabolism and discuss in detail the
metabolism of calcium with clinical significance.
(10)
3.
Write short notes on the following:
Radioisotopes
Regulation of gene expression
Wald’s Visual cycle
PEM
Creatinine clearance test
a)
b)
c)
d)
e)
4.
(3x5=15)
What are the fat soluble vitamins? Discuss role of vitaminD in the metabolism of calcium.
(5)
Supplementary MBBS I (First) Professional Examination 2015-16
Roll No.
Student’s Name
Student’s Signature
Invigilator’s Signature
Course Code: MBS103
Paper ID: S322242
Biochemistry - II
Part ‘A’
Time: 20 Minutes
Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
Q.1
The enzyme adenylate kinase is said to be
inhibited by:
a)
Insulin
b)
Glucagon
c)
Epinephrine
d)
Non-epinephrine
Q.2
Ribozymes are:
a.
Enzyme which uses ribose as
substrates
b.
Enzyme working on DNA
c.
RNA with enzymic activity
d.
Enzyme-RNA complex
Q.3
Component of cornea & cartilage is:
a)
Keratosulphate
b)
Chondroitin sulphate
c)
Cadmium sulphate
d)
Antimony sulphate
Q.4
Glycogen synthetase activity is depressed
by:
a)
Glucose
b)
Insulin
c)
C-AMP
d)
Fructokinase
Q.5
Lecithincombine with protein to form:
a)
Phosphoprotein
b)
Lipoprotein
c)
Mucoprotein
d)
Glycoprotein
Q.6
HDL is synthesized & secreted from:
a)
Pancreas
b)
Liver
c)
Muscle
d)
Kidney
Q.7
The predominant antibody in saliva is:
a)
Ig G
b)
Ig A
c)
Ig M
d)
Ig D
Q.8
Immunoglobulin in the serum of a new
born will be mostly:
a)
Ig M of maternal origin
b)
Ig G of maternal origin
c)
Ig M of endogenous origin
d)
Ig G of endogenous origin n
Q.9
Antigen-antibody binding do not involve:
a)
Vanderwaal forces
b)
Non-covalent bonding
c)
Hydrophobic interaction
d)
Covalent bonding.
Q.10
Most antibodies are synthesized by:
a)
Central lymphoid organ
b)
Peripheral lymphoid organ
c)
Primary lymphocytes
d)
Macrophages
Q.11
P.T.O.
Keratin , protein of hair , is synthesized
from amino acid:
a)
Glycine
b)
Serine
c)
Proline
d)
Methionine
Q.12
Glutathione is a:
a)
Dipeptide
b)
Polypeptide
c)
Tripeptide
d)
None of the above
Q.13
DNA is Denatured by:
a)
Heat
b)
Acid
c)
Alkali
d)
All of the above
Q.14
Bile is produced by:
a)
Liver
b)
Pancreas
c)
Intestine
d)
Gall bladder
Q.15
In blood there is a low concentration of
buffer:
a)
Haemoglobin
b)
Protein
c)
Oxyhaemoglobin
d)
Phosphates
Q.16
Depression of respiration is caused by:
a)
Excessive anesthesia
b)
Tartaric acid
c)
Guanine
d)
Cold
Q.17
High energy compound is:
a)
UDPG
b)
ATP
c)
ADP
d)
Arginine phosphate
Q.18
Concentration of serum calcium may drop
below 7mg/100ml in:
a)
Hyperparathyroidism
b)
Hypoparathyroidism
c)
Tetany
d)
Rickets
Q.19
Replicative polymerase in E. coli is:
a)
DNA polymerase I
b)
DNA polymerase II
c)
DNA polymerase III
d)
DNA polymerase IV
Q.20
Eukaryotic DNA synthesis is inhibited by:
a)
Aphidicoline
b)
Cyclohexamide
c)
Chloramphenicol
d)
Amphicillin