Download BDS Ist YEAR EXAMINATION 2008-09

MBBS I (First) Professional Examination 2011-12
Course Code: MBS103
Paper ID: 0322211
Biochemistry -II
Time: 2 Hours 40 Minutes
Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support
your answer.
Part ‘B’
1.
Describe the intracellular functions, dietary requirement,
sources and absorption of calcium ion in the human body.
Discuss the maintenance of calcium homeostasis.
(10)
2.
What are vitamins? Classify them. Describe in brief dietary
requirement,
sources,
functions
and
deficiency
manifestations of vitamin A. Give a note on hyper
vitaminosis of vitamin A.
(10)
3.
a)
b)
c)
4.
a)
b)
Write short notes on any two of the following:
Role of kidney in acid-base balance
Oncogenes
BMR and its influencing factors
(5+5)
A non-vegetarian 55 year old man, consuming alcohol
occasionally, complained severe pain in the joints. His
laboratory findings showed as follows:
Serum uric acid = 14 mg/dl, Blood urea = 300 mg/dl
Urinary uric acid = 3.0 g/day and Urinary pH = 4.5.
The patient responded to the treatment by the drugallopurinol.
What is the diagnosis of the disease?
Discuss the clinical interpretation of data and mechanism of
action of the drug allopuinol.
(10)
MBBS I (First) Professional Examination 2011-12
Roll No.
Student’s Name
Student’s Signature
Invigilator’s Signature
Course Code:MBS103
Paper ID: 0322211
Biochemistry - II
Part ‘A’
Time: 20 Minutes
Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
Q.1
Q.2
Na   K  pump
is
responsible
maintaining:
a)
High extracellular K  and
intracellular Na 
b)
High extracellular Na  and
intracellular K 
c)
Equal concentration of Na 
K  in the extracellular
intracellular fluids
d)
None of the above
low
and
and
The blood pH compatible to life :
a.
6.4-6.8
b.
6.8-7.8
c.
7.8-8.2
d.
8.2-9.2
The ratio of plasma bicarbonate to carbonic
acid:
a)
5:1
b)
10:1
c)
20:1
d)
40:1
Q.4
The excretory functions of liver can be
assessed by measured by measuring serum:
a)
Bile pigments
b)
Traansaminases
c)
Hippuric acid
d)
Albumin
Based on specific dynamic action, the best
source of energy:
a)
Carbohydrate b)
Protein
Fat
d)
Vitamins
Q.6
A positive nitrogen balance means that the
nitrogen intake is:
a)
Higher than the output
b)
Lower than the output
c)
Equal to that of output
d)
None of the above
Q.7
Kwashiorkor is primarily due to insufficient
intake of:
a)
Carbohydrates
b)
Fats
c)
Vitamins
d)
Proteins
Q.8
The hormone controlling water excretion
by the kidney:
a)
Vasopressin
b)
Oxytocin
c)
Aldosterone
d)
Cortisone
Q.9
The principal extracellular cation:
Na 
a)
b)
K
Ca 2
c)
d)
Mg 2
Q.10
The serum enzyme elevated in obstructive
jaundice:
a)
Alanine transaminase
b)
Aspartate transaminase
c)
Alkaline phosphatase
d)
Lactate dehydrogenase
low
Q.3
Q.5
c)
for
P.T.O
Q.11
Q.12
Renal threshold for glucose:
a)
100 mg/dl
b)
180 mg/dl
c)
280 mg/dl
d)
350 mg/dl
The most sensitive test to assess renal
function:
a)
Blood urea estimation
b)
Serum creatinine estimation
c)
Creatinine clearance test
d)
Urea clearance test
Q.13
Ryle’s tube is used in:
a)
Liver function test
b)
Renal tubular function test
c)
Pancreatic function test
d)
Gastric function test
Q.14
The proof-reading activity of the newly
synthesized DNA is present on the enzyme:
a)
DNA helcase
b)
DNA polymerase I
c)
DNA polymerase II
d)
DNA polymerase III
Q.15
The initiating codon in protein synthesis:
a)
UAA
b)
AUG
c)
UAG
d)
UGA
Q.16
The replacement of a purine base by
another purine base is referred to as:
a)
Transition point mutation
b)
Transversion point mutation
c)
Frame shift mutation
d)
None of the above
Q.17
The technique employed for amplification
of a selected DNA fragment:
a)
Replication
b)
Recombination
c)
Polymerase chain reaction
d)
Transformation
Q.18
Apoptosis means programmed cell:
a)
Growth
b)
Differentiation
c)
Development
d)
Death
Q.19
The tumor marker cancer antigen-125 is
used for the detection of:
a)
Cancer of colon
b)
Ovarian cancer
c)
Prostatic cancer
d)
Multiple myeloma
Q.20
The detoxification of aspirin involves:
a)
Oxidation
b)
Reduction
c)
Hydrolysis
d)
All of the above