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Dr. Kamal Dulai
Cell and Molecular Biology Spring 2007 Final Exam
Answer ALL 50 questions by marking your answers onto your Scantron. Take your time and understand each
question before you answer. Good Luck! Please return just the Scantron when finished. To save on paper, the
format is squeezed together in some places. This exam has a relative difficulty factor of 8/10
1
The smallest unit of life is? (select the best answer)
(a)
An electron
(b)
An atom
(c)
(e)
None of the above
A virus
(d)
A cell
2
The most reliable feature distinguishing prokaryotic and eukaryotic cells is?
(a)
one has a cell membrane and the other does not
(b)
one has ribosomes and the other does not
(c)
one has cytoplasm and the other does not
(d)
one has a nucleus and the other does not
(e)
None of the above
3
Which of the following organelles have a double membrane with pores? Think about it!
(a)
mitochondria
(b)
golgi apparatus
(c)
lysosome
(d)
nucleus
(e)
None of the above
4
How many chromosome pairs are there in a typical normal healthy sperm?
(a)
23
(b)
46
(c)
72
(d)
144
(e)
None of the above
5
The mitochondrion plays an important role as the cell’s?
(a)
Gatekeeper
(b)
Infection fighter
(c)
Power plant
(d)
Molecular tether
(e)
None of the above
6
Which of the following is not the same class of molecule as the rest?
(a)
Sugar
(b)
Monosaccharide
(c)
Carbohydrate
(d)
Protein
(e)
Polysaccharide
7
The plasma membrane of all known cells consists of?
(a)
Just lipids
(b)
Just proteins
(c)
Lipids and proteins
(d)
Just fats
(e)
None of the above
8
Atoms form covalent bonds with each other by?
(a)
sharing electrons
(b)
sharing protons
(c)
transferring electrons from one atom to another
(d)
sharing neutrons
(e)
attraction of positive and negative charges
9
In a DNA double helix?
(a)
the two DNA strands are identical
(b)
purines pair with purines
(c)
thymine pairs with cytosine
(d)
the two DNA strands run antiparallel
(e)
the nucleotides are ribonucleotides
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Dr. Kamal Dulai
10
All biological enzymes are?
(a)
Made of proteins
(b)
Decrease the rate of a reaction
(c)
The enzyme is altered as a result of the reaction
(d)
Made of RNA
(e)
None of the above
11
The name given to the process by which DNA is converted to RNA is?
(a)
Transformation
(b)
Translation
(c)
Transcription
(d)
Transduction
(e)
None of the above
12
The origin of mitochondria has been traced back to?
(a)
plants
(b)
viruses
(c)
bacteria
(d)
fungus
(e)
None of the above
13
Which of the following is a nonpolar amino acid?
(a)
Lysine
(b)
Arginine
(c)
(e)
None of the above
14
Nucleic acids are made of?
(a)
Phosphate, sugar, base
(b)
Protein, sugar, lipid
(c)
Phosphate, sugar, lipid
(d)
Protein, sugar, base
(e)
None of the above
15
Cytoplasmic proteins are degradation by the?
(a)
lysozyme
(b)
endosome
(c)
lysosome
(d)
proteasome
Aspartate
(e)
(d)
Glutamate
None of the above
16
The cell cycle is divided into phases. Irrespective of where one starts the correct order is? (select the
best answer)
(a)
-> G1 -> G2 -> S -> mitosis -> cytokinesis ->
(b)
-> S -> G2 -> mitosis -> cytokinesis -> G1 ->
(c)
-> G1 -> S -> G2 -> cytokinesis -> mitosis ->
(d)
-> cytokinesis -> mitosis -> G1 -> S -> G2 ->
(e)
None of the above
17
Which of the following organelles have a double membrane with pores?
(a)
mitochondria
(b)
golgi apparatus
(c)
lysosome
(d)
nucleus
(e)
None of the above
18
A threadlike material called chromatin is located within the?
(a)
golgi apparatus
(b)
nucleus
(c)
endoplasmic reticulum
(d)
lysosome
(e)
None of the above
19
Where is ribosomal RNA produced?
(a)
ribosomes
(c)
endoplasmic reticulum
(e)
None of the above
20
(b)
(d)
golgi apparatus
nucleolus
This is (are) the site of protein synthesis in the cytoplasm?
(a)
smooth endoplasmic reticulum
(b)
mitochondria
(c)
golgi apparatus
(d)
rough endoplasmic reticulum
(e)
None of the above
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Dr. Kamal Dulai
21
Embryonic stem cells come from which region of the developing egg?
(a)
Trophoblast
(b)
Blastocoel
(c)
Inner cell mass
(d)
Blastocyst
(e)
None of the above
22
Is it possible now to take a red blood cell and reverse program it so that it forms a stem cell? Think
about it!
(a)
Yes, it is
(b)
No, maybe in the future
(d)
None of the above
23
Which organelle contains hydrolytic enzymes that can digest macromolecules?
(a)
centrioles
(b)
lysosomes
(c)
endoplasmic reticulum
(d)
cytoskeleton
(e)
None of the above
24
Where can cristae be found?
(a)
centriole
(b)
nucleus
(c)
mitochondria
(d)
lysosome
(e)
None of the above
25
The number of proteins found in humans and other organisms can vastly exceed the
number of genes. This is largely due to: (one answer)
(a)
protein degradation
(b)
alternative splicing
(c)
homologous genes
(d)
synteny
(e)
mutation
26
Which one of the following statements about the cleavage furrow is FALSE?
(a)
It is a puckering of the plasma membrane caused by constriction of a ring of filaments attached
to the membrane.
(b)
It begins to form at the end of telophase.
(c)
It will not begin to form in the absence of a mitotic spindle.
(d)
It always forms perpendicular to the interpolar microtubules.
27
How many sperm and eggs result from meiosis in mammals, respectively?
(a)
1 and 1
(b)
1 and 4
(c)
4 and 4
(d)
4 and 1
(e)
None of the above
28
The microtubules which attach to the chromatids do so at a region known as?
(a)
Kitson
(b)
Kittenson
(c)
Kipper
(d)
Kinetosome
(e)
Kinetochore
29
What is a phragmoplast?
(a)
A type of drug
(b)
A mutated chloroplast
(c)
A type of cell communication
(d)
A digestive organelle in plants
(e)
None of the above
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Dr. Kamal Dulai
30
Sister chromatids are transformed into chromosomes through the indirect action of which one of the
following?
(a)
Cohesin activation
(b)
Anaphase promoting complex
(c)
Phosphorylation of lamins
(d)
Dephosphorylation of lamins
(e)
None of the above
31
The process of centrosome duplication and separation is known as the? (select the best answer)
(a)
centrosome duplication phase
(b)
S phase
(c)
centrosome cycle
(d)
mismatch repair system
(e)
None of the above
32
Mitosis has six stages. Which is the correct order?
(a)
Prophase, Metaphase, Telophase, Anaphase, Cytokinesis, Prometaphase
(b)
Prophase, Prometaphase, Metaphase, Telophase, Anaphase, Cytokinesis
(c)
Prophase, Cytokinesis, Prometaphase, Metaphase, Telophase, Anaphase
(d)
Interphase, Prometaphase, Metaphase, Telophase, Anaphase, Cytokinesis
(e)
None of the above
33
During the M phase of cell division, the chromatids are condensed by proteins called?
(a)
cohesins
(b)
condensins
(c)
cytochromes
(d)
selectins
(e)
None of the above
34
Sister chromatids are held together by which protein?
(a)
chromatin
(b)
cohesins
(c)
DNA ligase
(d)
DNA topoisomerase
(e)
None of the above
35
Multicellular organisms sent signals from other cells in the body to control cell numbers. These signals
can be classified into three categories. Which of the following is not one of them?
(a)
Mutagens
(b)
Survival factors
(c)
Growth factors
(d)
Mitogens
(e)
None of the above
36
Which protein class plays a very prominent role in the pathways leading to cell death through
apoptosis?
(a)
caspases
(b)
ligases
(c)
kinases
(d)
proteases
(e)
None of the above
37
Which of the following organelles is a key player in apoptosis?
(a)
Chloroplast
(b)
Mitochondria
(c)
Vacuole
(d)
Lysosome
(e)
None of the above
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Dr. Kamal Dulai
38
Motor proteins travel within the cell along ‘cellular highways’, formed by which type of filament? (select
the best answer)
(a)
Actin filaments
(b)
Intermediate filaments
(c)
Transport filaments
(d)
Microtubules
(e)
None of the above
39
With respect to the above question, Dyneins move material towards which end of the filament?
(a)
Left
(b)
Right
(c)
Plus
(d)
Minus
(e)
None of the above
40
Proteins may have phosphate groups added to certain amino acids. Which class of enzyme removes
such groups? (select the best answer)
(a)
Kinases
(b)
Phosphatases
(c)
Polymerases
(d)
Proteases
(e)
None of the above
41
Most microtubules tend to grow from a central location within the cell called the?
(a)
Cascade center
(b)
Centromere
(c)
Centimeter
(d)
Centrosome
(e)
None of the above
42
The nuclear envelope is supported by a meshwork of intermediate filaments which are formed from?
(a)
lemins
(b)
lemons
(c)
laminins
(d)
lamins
(e)
None of the above
43
Which property of intermediate filaments is not true? Think about it!
(a)
These have great tensile strength
(b)
Toughest and most durable of the three types
(c)
Enable cells to withstand the mechanical stress associated with stretching
(d)
Their diameter is 0.0001nm
(e)
None of the above
44
The cytoskeleton is built on three types of protein filaments. Which is not one of them?
(a)
Actin filaments
(b)
Intermediate filaments
(c)
Microtubles
(d)
Protein filaments
(e)
None of the above
45
Which is the most appropriate statement about signal transduction?
(a)
All cellular responses are instant
(b)
All cellular responses take many hours
(c)
Cellular responses are variable at different times of the day
(d)
Cellular responses range from quick to slow
(e)
None of the above
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Dr. Kamal Dulai
46
There are three classes of cell surface receptor involved in signal transduction. Which is not one of
them?
(a)
Ion-channel linked
(b)
G-protein linked
(c)
Enzyme linked
(d)
Signal cascade
(e)
None of the above
47
What is a signal cascade?
(a)
The movement of water within the cell
(b)
A signal required to start the cell moving
(c)
A sign that the cell is in distress
(d)
A system of relaying information from the site of reception to the point of action
(e)
None of the above
48
Cells which are deprived of external signals do what?
(a)
Move about uncontrollably
(b)
Attack their neighbors
(c)
Show no changes in behavior
(d)
Die
(e)
None of the above
49
Which of the cell-to-cell junctions doe not provide a mechanical basis?
(a)
Desmosomes
(b)
Tight Junctions
(c)
Gap Junctions
(d)
Adherens
(e)
None of the above
50
Which type of cell junction prevents material from passing between cells ?
(a)
Desmosomes
(b)
Tight Junctions
(c)
Gap Junctions
(d)
Adherens
(e)
None of the above
THE EXAM IS FINISHED. SHOULD YOU HAVE TIME PLEASE REVIEW YOUR ANSWERS. THANK YOU
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