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Download Chem 231 Exam #3 Study Guide
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Chem 231 Exam #4 Study Guide * Please be aware that this is only a guide for studying. Don’t rely solely on this sheet! The exam will take place in Oly204 from 6-7pm on Monday, December 11th. The exam will be worth 50 pts and you will be given 1 hour. You will not be allowed to use any materials for the exam. The exam will cover materials from Chapters 6-7.7. The exam will consist of a mixture of multiple choice and short answer questions. Questions will be similar to the suggested homework problems from the book and in-class activities. In General: Be able to draw R and S molecules Be able to draw the mechanisms for an SN2, SN1, E1, and E2 reaction Know what the free energy diagram looks like for an SN1 versus an SN2 reaction and be able to label the reactants, products, intermediates, and transition states Know the factors that effect SN2, SN1, E1, and E2 reactions Know the order of substrate reactivities for the different reactions Know how to predict nucleophilicity (two rules) and the relative order of nucleophiles in protic solvent Be able to predict a good versus bad leaving group Know how solvents effect SN1 versus SN2 reactions Know how to name alkenes with (E)-(Z) designations Know overall stability of alkenes Know the mechanism for the dehydrohalogenation of alkyl halides and how to predict whether a reaction will follow Zaitsev’s or Hofman’s rules Know the mechanism for the acid-catalyzed dehydration of secondary and tertiary alcohols versus primary alcohols Be able to predict the products or reactants of a reaction and label the major products. So you should know the factors that will favor an SN2, SN1, E1, or E2 reaction. If given a reaction, be able to predict whether it is an SN2, SN1, E1, or E2 reaction and explain your reasoning Know the definition and meaning of the following terms: Substitution reaction Elimination reaction Nucleophile Substrate Leaving group Polar aprotic solvent Polar protic solvent solvolysis Inversion of configuration Racemization Transition state Steric effect SN2 SN1 E1 E2 Dehydration Dehydrohalogenation (E)-(Z) system Hofman Rule Zaitsev’s rule Anti coplanar -elimination (1,2-elimination)