* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download DNA Replication
Synthetic biology wikipedia , lookup
DNA barcoding wikipedia , lookup
DNA sequencing wikipedia , lookup
Holliday junction wikipedia , lookup
Comparative genomic hybridization wikipedia , lookup
Agarose gel electrophoresis wikipedia , lookup
Molecular evolution wikipedia , lookup
Community fingerprinting wikipedia , lookup
Maurice Wilkins wikipedia , lookup
Bisulfite sequencing wikipedia , lookup
DNA vaccination wikipedia , lookup
Non-coding DNA wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Biosynthesis wikipedia , lookup
Gel electrophoresis of nucleic acids wikipedia , lookup
Transformation (genetics) wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
Molecular cloning wikipedia , lookup
Cre-Lox recombination wikipedia , lookup
Biology DNA Replication Name: _____________ Period: ___ Date:________ Part I: DNA REPLICATION – How DNA is copied. Use page 297 - 299 in the textbook to answer the following questions (not in order of the book ). 1. Define DNA replication. 2. When and why does DNA replication occur? 3. According to Watson and Crick’s double helix model the two strands of DNA are complementary to each other, what does that mean? 4. What is the role of enzymes in DNA replication? DNA POLYMERASE 5. What is the result of DNA replication (page 299)? Biology DNA Replication Name: _____________ Period: ___ Date:________ Part II: Notes on DNA Replication: Part III: LETTER TO LARRY: DNA REPLICATION – With a bright color marker highlight the mistakes in poor cousin Larry’s letter. Number each mistake and write the correct word at the bottom. The number in parentheses tells your how many errors are in the paragraph! Dear Cousin, How’s it going? Did you know that DNA is nicknamed “The Code of Life?” for real? I’ve been learning all about it in my biology class. It’s so exciting that I thought I’d share my newly found knowledge with you. Biology DNA Replication Name: _____________ Period: ___ Date:________ (3) As you know, DNA is found within the vacuole of the cell. In order for each cell to function properly, it must have the correct amount of DNA. So, before cells divide, the DNA must replicate. DNA replication is kind of tricky, though, because the square shape of the molecule prevents contact with enzymes, which are specialized carbohydrate molecules that help speed up chemical reactions. I’d better take you through this amazing process step by step. (5) First, an enzyme unwinds and unzips the DNA molecule. The unzipping occurs when the ionic bonds between base pairs are broken and the two strands of the molecule unwind. Each strand serves as a template for the attachment of complementary bases. Addition of new amino acids can’t begin, though, until an RNA primer is added by the enzyme primase. Once primed, DNA polymerase adds new nucleotides to the DNA molecule. The nitrogen base adenine always pairs with guanine and cytosine always pairs with thymine. DNA proofreaderase also “proofreads” each new DNA strand, helping to maximize the odds that each molecule is a perfect copy of the original DNA. Pretty cool, huh? (2) DNA replication results in three molecules of DNA each, consisting of one parental or template strand and one newly synthesized strand, thus the strands are known to be compensatory. Isn’t it great? And to think that this complex process is taking place inside our cells at this very instant. Well, I hope school is going well and you had a wonderful Spring Break!! Cousin Larry 1. ____________________________ 6.______________________________ 2. ____________________________ 7. ______________________________ 3. ____________________________ 8. ______________________________ 4. ____________________________ 9. ______________________________ 5. ____________________________ 10. ______________________________ Biology DNA Replication Color this page! Phosphate-Pink, Deoxyribose-Blue, A-Green, T-Orange, G-Purple and C-Yellow Name: _____________ Period: ___ Date:________