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Transcript
Supplemental Digital Content 1 - Figure 1. Global Gene Expression Analysis of Similarities in Biopsies. A data set consisting of ten biopsies
from one patient projected by correspondence analysis to reveal similarities in global gene expression levels between different samples. Genes
and samples that are associated are located in the same spatial direction from the origin, where distance is a measure of difference. Therefore,
expression profiles that differ the most are farthest away from the origin. Before liver transplantation, the gene expression profiles of the liver
graft and the native liver differed substantially. After 1 week in the recipient, the liver graft had a gene expression profile resembling that of the
native liver. In opposite, the global gene expression in the kidney transplant only underwent minor changes during the transplant procedure. K,
kidney; TL, transplanted liver; NL, native liver. Genes are shown as a gradient colored density map.
TL 4h
TL 1h
TL 0h
K Day 7
K 1h
K 0h
NL Day 7
NL 1h
TL Day 7
NL 0h