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Cell Structure and Function Galileo Galilei arranged two glass lenses within a cylinder, and used it to look at an insect. He was not a biologist was the first to record observations through a microscope. He took slices of cork from a mature tree and observed the tiny compartments in the sample and gave them the Latin name, cellulae, meaning small rooms. This later became the term “cell.” Was exceptional in constructing lenses. He began looking at everything he could. Notices opaque spots in cells and named them nucleus. Discovered that cells develop as independent units even though they are part of a larger whole. Studied animal tissues and noticed that cells are part of the organism, but to some extent have a life of their own. 1) 2) 3) Every organism is made of one or more cells. Cell is the smallest unit that has all of the basic properties of life. Cells come from preexisting cells. Prokaryotes are simpler cells. They lack a nucleus and other membrane bound organelles. They do contain ribosomes to perform protein synthesis. Despite their simplicity, they have the ability to survive in very diverse habitats. Eukaryotes are more complex cells. They have a nucleus and membrane bound organelles 1) 2) They have a plasma membrane surrounding them made of a phospholipid bilayer. This membrane determines what substances may enter and leave the cell. They have a DNA containing region. • • 3) In a prokaryote cell, it is simply a circular piece of DNA called a plasmid. In eukaryote cells, the genetic material is contained in a nucleus. They have cytoplasm. Cytoplasm is the substance between the cell membrane and the DNA region. It is a fluid substance that contains the organelle Fluid Mosaic Model Cells are surrounded by fluids, inside the cell itself and around it. The membrane is a flexible substance that allows the cell to move around in this fluid environment. This is referred to as the fluid mosaic model The membrane is made up of various substances – phospholipids, sterols, proteins, and glycolipids. All of these components are working together for the membrane to function properly. The fluid quality comes from the ability of the membrane to move and adapt to the surrounding environment. It is not a rigid barrier, but a flexible one Membrane Proteins: Proteins in the surface of the cell carry out most membrane functions. Enzyme – to carry out metabolic functions Transport – span the bilayer to allow water soluble substances to move through their interior Receptor – bind extracellular substances that can trigger changes in cellular activity Recognition – identify cells of a certain type (ex: recognizing “self”) Adhesion – help cells of the same type locate each other and stick together and stay positioned in proper tissues Surface to volume ratio As a growing cell expands, the volume increases faster than the surface area. Cell size is limited to the surface area. Smaller cells can move around more easily than larger ones http://www.gap- system.org/~history/PictDisplay/Galileo.html http://rationalwiki.org/wiki/File:Robert_Hoo ke_portrait.jpg http://www.ucmp.berkeley.edu/history/leeu wenhoek.html http://www.answers.com/topic/matthiasjakob-schleiden http://www.nndb.com/people/357/0000960 69/