Download Worksheet 13.3

Biology Honors I!
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Name ___________________ Period ___
Worksheet 13.3: Mutations
(pages 372-376; iBooks pages 630-637)
1. What are mutations? ______________________________________
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2. __________ True or False: Chromosomal mutations result from changes in a single
gene
3. Mutations that occur at a single point in the DNA sequence are called
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4. A mutation involving the insertion or deletion of a nucleotide is a(n) ______________
mutation.
5. Fill in the concept map.
Point Mutations
Substitution
6. Use the words in the box to add headings to the three lower parts of the diagram.
insertion
deletion
substitution
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Biology Honors I!
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Name ___________________ Period ___
Complete the following sentences by using the terms in the box found in the previous
question.
7. In a(n) _________________________, one base is changed to a different base.
8. In a(n) _________________________, a base is inserted into the DNA sequence.
9. In a(n) _________________________, one base is removed from the DNA
sequence.
10. Which of the following can result in a frameshift mutation? Circle each correct
answer.
A. deletion
B. substitution
C. insertion
11. Why is a frameshift mutation more damaging than a substitution?
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12. Write the name of the chromosomal mutation underneath each chromosome in the
left column.
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Original Chromosome!!
AB C
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JK LDE F
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A B B C
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CB F
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ABC
DE F
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DE F
AE D
DE F
AB C
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Mutation
A C
DE F
AB C
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DE F
AB C
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DE F
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Biology Honors I!
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Name ___________________ Period ___
13. Use the above diagram to help you fill in the table.
Chromosomal Mutation
Description
Part of the chromosome is lost.
Extra copies of a part of a chromosome are made.
Part of a chromosome breaks off and attaches to
another chromosome.
Sections of a chromosome are reversed.
14. Which types of chromosomal mutations can add genes to a chromosome?
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15. Which type of chromosomal mutation can take genes away from a chromosome?
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16. Which type of chromosomal mutation changes the order of the genes, but not the
number of genes in a chromosome?
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17. What is polyploidy? __________________________________________________
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18. Using your notes, explain how a silent mutation occurs.
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