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Download Intro to Anatomy and Physiology Intro and Cellular Anatomy
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Anatomy and Physiology Know the difference! Anatomy is the study of an organism's body structures and their locations. Physiology is the study of the functions of each body part. Remember, Anatomy is STRUCTURE Physiology is FUNCTION When the Structure and Function of the body is in balance, all of the ‘parts’ of the body work together. This state of Balance in the human body is called HOMEOSTASIS Body Organization The body is organized as follows: Cell Tissue Organ System Cells The smallest • Recall, from medical structural terminology, the root word (or meaning cell is CYTE. This anatomical) will help you as you learn unit of the about various cell types human body throughout the body is the CELL Cells Cells perform several functions • • • • • Taking in food and oxygen Producing heat and energy Eliminating wastes Performing unique tasks Reproducing to create new, identical cells Parts of the cell The Cell membrane – The outer covering of the cell, or cell wall. It is semi-permeable (think contact lens) meaning some things can travel through the wall and others cannot Parts of the cell Cytoplasm • The cytoplasm is the sticky, fluid like interior of the cell. It transports substances within the cell and is also the site where chemical reactions take place Nucleus • The nucleus is the ‘brain’ of the cell located near the center of the cell. It directs the cell in reproduction and controls many of the cells functions Organelles • Within the cytoplasm of the cell, there are many smaller structures that carry out specific functions. Mitochondria • Mitochondria are referred to as the ‘powerhouse’ of the cell. This is where energy is produced in the form of ATP (adenosine triphosphate) Mitochondria break down nutrients to form ATP. Ribosomes • Ribosomes help make protein. They are formed inside the nucleus out of protein and RNA (ribonucleic acid) After they are formed in the nucleus the travel to the cytoplasm where they either float freely or attach themselves to the endoplasmic reticulum Endoplasmic Reticulum • The fine network of tubules that transports substances in and out of the cell nucleus is called the endoplasmic reticulum. The endoplasmic reticulum also helps in the production and storage of protein Centrioles • The centrioles are key in the process of cell division. A single pair of centrioles live near the nucleus of the cell. The golgi apparatus • The sewer system of the cell! • The golgi apparatus is a stack of membrane layers that transport secretions(garbage) out of the cell Lysosomes • Lysosomes protect the cell from foreign invaders. They contain enzymes that allow them digest foods. They use these enzymes to destroy bacteria Cellular Metabolism Metabolism is the sum of all chemical reactions that take place in a cell. Metabolism consists of Anabolism and Catabolism Metabolism Anabolism is the process of building up complex substances from simpler ones. Catabolism is the process of breaking down complex substances into simpler ones. This process releases energy Cell reproduction Cells reproduce in two ways • Mitosis, which is cell division. A non-sexual reproduction which aids the body in replacing old, damaged cells with new ones. • Meiosis, which is the basis for sexual reproduction Mitosis • In the process of mitosis, a single cell condenses and produces two cells. Each mitotic cell contains 46 chromosomes (think skin cell) Meiosis • Meiosis is sexual reproduction. Each cell contains 23 chromosomes. (think egg or sperm) Comparison of Meiosis to Mitosis Problems on the cellular level can by caused by aging, lack of oxygen, disease, bacteria or viruses • Atrophy: • A decrease in size of cells as a result of aging or disease. • Hyperplasia: • An increase in the number of cells. • Metaplasia: • Cells being replaced by another type of cell. • Dsyplasia: • Cells changing in shape or organization. • Neoplasia: • Cells changing in structure with an uncontrolled growth pattern. Tumors Sometimes cells divide in an unusual or abnormal way. The cell division can result in tumor formation • A tumor is also knows as a neoplasm Neoplasms (tumors) There are two types of neoplasms • A benign neoplasm is one in which the tumor is confined to the area in which they are formed. It is non-cancerous and can be removed through surgery • Usually, benign neoplasms are relatively harmless, though they can cause inconvenience or discomfort. Benign neoplasms in the brain or spinal cord can be life threatening Cancer A Malignant Neoplasm is cancerous. As abnormal cells reproduce, they crowd out or invade normal cells. They interfere with the functioning of the specific organ or body part. Malignant neoplasms can, and often do spread to other parts of the body. This is called Metastasis Common locations for cancer • • • • • • • Mouth Lungs Breast Colon Uterus Bone marrow However, there are many, many different forms of cancer, and it can develop virtually anywhere in the body Cancer continued • As we talk about each part of the body, we will discuss cancer in more detail. • Depending on the location of the cancer, early warning signs and symptoms vary. • Treatments for cancer include surgery, chemotherapy, and radiation. All of these options have side effects and consequences to normal cells Tissue When cells of the same type join together for a common purpose Tissue is formed. There are 4 types of tissue in the human body • Epithelial • Connective • Nerve • Muscle Epithelial tissue Epithelial tissue • Covers organs • Lines body cavities • Covers inside and outside body surfaces • Forms glands • Is the main tissue involved in skin Connective tissue •Forms bones •Holds body parts Connective together tissue •Can be hard or soft, fat, cartilage, bone, etc Muscle Muscle tissue contracts to help the body move Nerve Tissue Nerve tissue • Nerve tissue carries messages throughout the body to direct it’s activities. • The brain and spinal cord are comprised of nerve tissue ORGANS An Organ is formed when tissues of the same type join together to perform a specific task. Examples of organs: • Heart • Lungs • Kidney • liver Organ systems • An organ system is comprised of multiple organs working together to complete a common task(s) • Organs in a system are both independent and interdependent • Independent in that they perform some functions by themselves • Interdependent in that they need each other to complete some functions Organ systems of the human body • • • • • • • • • • • • Integumentary system Skeletal system Muscular system Nervous system Sensory system Cardiovascular system Lymphatic system Respiratory system Digestive system Urinary system Endocrine system Reproductive system Homeostasis • Homeostasis refers to a state of balance in the human body. • In order to achieve this balance, all organ systems must be working properly • Fluid balance, electrolyte balance, rest, nutrition, temperature, and oxygen all play a major role Interdependence • We know that organs within a system work independently and interdependently, but systems also work interdependently. – Muscular and skeletal systems work together – Cardiovascular, respiratory, and urinary work together – Nervous system and sensory system Interdependence, cont • Because the systems all work so closely with one another, a problem with one system can manifest itself into problems in other systems The cost of a broken leg…… • Betty broke her leg, causing damage to her skeletal system. – Betty laid motionless for a long time because of pain, causing blood to pool and clot in her circulatory system – A blood clot traveled to her lung, affecting her respiratory system – A lack of oxygen from the respiratory system caused damage to the brain, part of the Nervous system – After weeks of immobilization, her muscles atrophied, causing problems with her muscular system Immunity • There are two types of immunity • Natural immunity- the immunity to certain things that we are born with • Acquired immunity – the immunity to certain things that we develop Acquired immunity • When a body is exposed to certain invaders it creates antibodies to fight the invader, then it tries to make itself permanently immune to the invader Acquired immunity • Natural acquired immunity is caused by unintentional exposure. For example, people who get measles and recover normally do not get them again. • Artificial acquired immunity is caused by intentional exposure. For example, a person may be injected with a vaccine that contains a very mild form of a disease. In response, the body creates antibodies for the disease. This process is called immunization. Active or passive • Passive acquired immunity is borrowing antibodies from another person or species, and it lasts a short time. For example, a person who has a poisonous snakebite must be given a dose of antitoxin immediately. • Active acquired immunity occurs when people develop their own antibodies. It is preferred because it lasts longer. The Skeletal System • Provides shape and support to the body • Protects vital organs • Acts as a set of levers, and together with muscles helps a person move • Produces blood cells • Stores calcium The skeletal system • The skeletal system is comprised of 206 bones, cartilage and joints. • It is made of connective tissue • It’s the ‘framework’ for the human body Types of bones • Bones are classified by shape into four categories • Long • Flat • Short • irregular Long bones • Are longer than they are wide. Long bones form the arms and legs. • They contain a lot of bone marrow Flat bones • Have a broad, flat shape. • They make up the pelvis and skull as well as shoulder blades. • They provide a large surface area for muscles to attach Short bones • Are about as wide as they are long. • Make up the bones of the wrists and ankles Irregular bones • ……. Bones that don’t fit into another category. They are the bones of the spine, ear, and face. LONG BONES • The long part of the bone is known as the diaphysis, or shaft. • Each end of the bone is covered by the epiphysis • The epiphysis is covered by cartilage to help reduce shock where bones rub