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Transcript
KRISHANU RAY’S LAB
DEPARTMENT OF BIOLOGICAL SCIENCES
TATA INSTITUTE OF FUNDAMENTAL RESEARCH
Research focus
Molecular Cell Biology of Intracellular transport
Stem cell proliferation and differentiation
Drosophila melanogaster
Neurons as model system for studying intracellular
transport
Axon
Dendrite
Synapse
Nucleus
Deciding the
destinations
Motor start and
stopping
coordination of
movements
Aparna Sadananda
RAB4::mRFP contaning
vesicle in the segmental nerve
Anuttama Kulkarni
AChE in lch5 axons
Swagata Dey
ChAT in lch5 axon
ChAT
GFP
How does Kinesin-2 transport different cargos in axons?
How do the sensory cilia develop & its implications?
Drosophila testis as a model to study cell biology of
proliferation and differentiation
Understanding how microenvironment of cells
regulate their fate
Stem cell
Progenitor cell
Amplification
Differentiation
Differentiated cells
The different signalling in the somatic
cyst cells and their effects on the
transit amplification of the germline
stem cell progeny.
Pankaj Dubey
Mechanism of sperm release
in Drosophila testis.
What happens when you poke a cell?
It reacts by mounting F-actin dynamics at the site.
F-actin
Sperm head
1
HCC
2
3
4
5
TCC
WASp
F-actin
Spermatid Spermatid
nucleus
tails
Dynamin
WASp/Dynamin refractory zone
Pankaj Dubey
Krishanu
Ph.D.
M.Sc.
Ayan
Dipti
Anuttama
Samir
Post Doc.
Swagata
Chetan
Rajarshi
JRF
Samir
Zoheb
Purna
Tushna
Pranali
Pooja
Priya