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AP Biology Discussion Notes Wednesday 2/01/2017 Goals for Today • Be able to decode the message in messenger RNA (mRNA) • Be able to name and describe the two major steps of protein synthesis (how proteins are made) • Be able to list the molecules & structures involved in Transcription & Translation. DNA assignment 2/1 Question of the Day • Identify and write in the processes within protein synthesis that are abbreviated by the arrows. Then list the necessary enzymes & molecules for each process. • DNA RNA Protein 2/1 Question of the Day • Identify and write in the processes within protein synthesis that are abbreviated by the arrows. Then list the necessary enzymes & molecules for each process. • DNA RNA Protein Protein Synthesis Lets put it all together! Create the mRNA, tRNA and find the Amino Acid coded for on mRNA Pick a decoder Create the mRNA, tRNA and find the Amino Acid coded for on mRNA Create the mRNA, tRNA and find the Amino Acid coded for on mRNA Important!….. • The genetic code is REDUNDANT • but NOT AMBIGUOUS (It is Unambiguous) What else besides Amino Acids do you see in your chart? How do you figure these things out? • Any ideas how you would start if you don’t know any of this? Nobel Winners Physiology & Medicine 1968 The Nobel Prize in Physiology or Medicine 1968 was awarded jointly to Robert W. Holley, Har Gobind Khorana and Marshall W. Nirenberg "for their interpretation of the genetic code and its function in protein synthesis". Is this genetic code Universal? • Do all organisms have DNA? • Do all organisms have RNA? • Do all organisms’ RNA code for proteins in the same way (Same codon = same AA)? The (near) universality of the genetic code is what allows transformation to work. DNA from one organism can be put into another (AND FUNCTION) in that other organism!!!! The (near) universality of the genetic code If I insert the gene (code for 1 _______ ) into another organism, what should that organism be able to do with it? (What are the 2 things organisms can do with DNA?) The (near) universality of the genetic code If I insert the gene (code for 1 Protein) into another organism, what should that organism be able to do with it? REPLICATE IT & MAKE PROTEINS CODED FOR! Transformation Lab Transformation Lab The (near) universality of the genetic code is what allows – transformation to work. National Geographic Story: • http://news.nationalgeographic.com/news/ 2009/05/photogalleries/glowing-animalpictures/ On 2/01/2017 I _______ _______ learned how to decode the code in all* living things. *almost all Let’s simplify before we complicate Be Student #1 • Student #1 – Explains protein synthesis (perfectly) to student #2. • Student #2 – disagrees about process • Student #1 – Have you read the story? • Student #2 – No • Student #1 – Read the story it makes sense, a lot of sense! 2/1 Species of the Day • Leopard Seal – Hydrurga leptonyx 2/1 Species of the Day • Leopard Seal – Hydrurga leptonyx What do you know about the RNA of this leopard seal? (You should have a pretty good list by now, including processes that the RNA is involved in)