
Repair of larynx, trachea, and other fibrocartilaginous tissues
... a multi-sequence alignment of a family of related proteins. Once the alignment betWeen the candidate sequence and the seven-cysteine domain is made and re?ned, a percent homology score is calculated. The aligned amino acid resi dues of the tWo sequences are compared sequentially for their similarity ...
... a multi-sequence alignment of a family of related proteins. Once the alignment betWeen the candidate sequence and the seven-cysteine domain is made and re?ned, a percent homology score is calculated. The aligned amino acid resi dues of the tWo sequences are compared sequentially for their similarity ...
procite - UWI St. Augustine
... asparagine residue is glycosylated, due to the fact that the folding of the protein plays an important role in the regulation of N-glycosylation [2]. It has been shown [3] that the presence of proline between Asn and Ser/Thr will inhibit N-glycosylation; this has been confirmed by a recent [4] stati ...
... asparagine residue is glycosylated, due to the fact that the folding of the protein plays an important role in the regulation of N-glycosylation [2]. It has been shown [3] that the presence of proline between Asn and Ser/Thr will inhibit N-glycosylation; this has been confirmed by a recent [4] stati ...
Regulation of mitochondrial calcium in plants versus animals
... Ca2+ acts as an important cellular second messenger in eukaryotes. In both plants and animals, a wide variety of environmental and developmental stimuli trigger Ca2+ transients of a specific signature that can modulate gene expression and metabolism. In animals, mitochondrial energy metabolism has l ...
... Ca2+ acts as an important cellular second messenger in eukaryotes. In both plants and animals, a wide variety of environmental and developmental stimuli trigger Ca2+ transients of a specific signature that can modulate gene expression and metabolism. In animals, mitochondrial energy metabolism has l ...
Purification and Characterization of Chorismate
... gracilis, the organization of the prechorismate pathway appears to resemble that found in fungi. The first and the last steps are catalyzed by single enzymes (DAHP-synthase and chorismate synthase, respectively), whereas activities 2 to 6 form a large complex resembling the fungal arom complex (27). ...
... gracilis, the organization of the prechorismate pathway appears to resemble that found in fungi. The first and the last steps are catalyzed by single enzymes (DAHP-synthase and chorismate synthase, respectively), whereas activities 2 to 6 form a large complex resembling the fungal arom complex (27). ...
Identification and first characterization of pairing
... risk (Ross et al., 2012). Besides the resulting and underestimated socio economic importance (King, 2010), schistosomes are also of basic economic relevance as they can infect animals as well (Quack et al., 2006; DeBont & Vercruysse, 1998). Pathology is not induced by adult worms, but by eggs. One f ...
... risk (Ross et al., 2012). Besides the resulting and underestimated socio economic importance (King, 2010), schistosomes are also of basic economic relevance as they can infect animals as well (Quack et al., 2006; DeBont & Vercruysse, 1998). Pathology is not induced by adult worms, but by eggs. One f ...
Complete genome sequence of the prototype lactic acid bacterium
... basis of the presence of potential ribosomal binding sites, sequence alignments, and available data in the literature. Potential alien genes on the L. lactis genome sequence were identified using the program SIGI (for score-based identification of genomic islands) (69), based on the scoring of codon ...
... basis of the presence of potential ribosomal binding sites, sequence alignments, and available data in the literature. Potential alien genes on the L. lactis genome sequence were identified using the program SIGI (for score-based identification of genomic islands) (69), based on the scoring of codon ...
Functional Interactions Between the Subunits of the Lactose
... proteoliposomal system) this can be determined from the summed activity of all species. However, in whole cells, the ratio of two separately expressed subunits is difficult to control, because of variations in the expression and inaccuracies in the determination of protein levels from, for instance, ...
... proteoliposomal system) this can be determined from the summed activity of all species. However, in whole cells, the ratio of two separately expressed subunits is difficult to control, because of variations in the expression and inaccuracies in the determination of protein levels from, for instance, ...
Food/feed and environmental risk assessment of insect
... The genetically modified maize stack 1507 x 59122 was produced by conventional breeding between inbred lines of maize containing the 1507 and 59122 events. The hybrid was developed to provide protection against certain lepidopteran and coleopteran target pests, and to confer tolerance to ...
... The genetically modified maize stack 1507 x 59122 was produced by conventional breeding between inbred lines of maize containing the 1507 and 59122 events. The hybrid was developed to provide protection against certain lepidopteran and coleopteran target pests, and to confer tolerance to ...
Systems Biotechnology of Pseudomonas putida for the enhanced
... transcriptome, proteome, and metabolome analyses were employed to investigate the metabolic responses under such limiting conditions. Dual limitation showed different expression patterns in comparison to those observed under strict carbon- or nitrogen-limiting conditions. Energy metabolism, fatty ac ...
... transcriptome, proteome, and metabolome analyses were employed to investigate the metabolic responses under such limiting conditions. Dual limitation showed different expression patterns in comparison to those observed under strict carbon- or nitrogen-limiting conditions. Energy metabolism, fatty ac ...
Calreticulin, a multi-process calcium
... folding and assembly, while calreticulin and calnexin interact with nascent glycoproteins via polypeptide and lectin binding [2]. PDI and ERp57, both thiol oxidoreductase folding factors, utilize the oxidizing environment of the ER to generate disulfide linkages, with the formation of intra- and int ...
... folding and assembly, while calreticulin and calnexin interact with nascent glycoproteins via polypeptide and lectin binding [2]. PDI and ERp57, both thiol oxidoreductase folding factors, utilize the oxidizing environment of the ER to generate disulfide linkages, with the formation of intra- and int ...
Raines, ChemRev 1998
... groups in proteins.23,24 Although such changes can be made by either total synthesis or semisynthetic procedures, they can be much easier to effect by sitedirected mutagenesis of a gene expressed in a heterologous host. The heterologous production of RNase A has been problematic. The difficulty has ...
... groups in proteins.23,24 Although such changes can be made by either total synthesis or semisynthetic procedures, they can be much easier to effect by sitedirected mutagenesis of a gene expressed in a heterologous host. The heterologous production of RNase A has been problematic. The difficulty has ...
Understanding the Regulation of Metabolic Enzyme Acetylation in E
... Global protein acetylation is a newly discovered phenomenon in bacteria. Of the more than 250 acetylations reported in E. coli, many are of metabolic enzymes [1-3]. Thus, acetylation could represent a novel posttranslational mechanism of metabolic control. Yet, almost nothing is known about the regu ...
... Global protein acetylation is a newly discovered phenomenon in bacteria. Of the more than 250 acetylations reported in E. coli, many are of metabolic enzymes [1-3]. Thus, acetylation could represent a novel posttranslational mechanism of metabolic control. Yet, almost nothing is known about the regu ...
Technical Brief
... Compared to children with marasmus, children with kwashiorkor are more apathic. They often suffer from anorexia, but in the absence of a quantitative measure, it is not clear whether this is more pronounced than in marasmus. Children with kwashiorkor seem susceptible to an excessive sodium load lea ...
... Compared to children with marasmus, children with kwashiorkor are more apathic. They often suffer from anorexia, but in the absence of a quantitative measure, it is not clear whether this is more pronounced than in marasmus. Children with kwashiorkor seem susceptible to an excessive sodium load lea ...
Regulation of Phenylalanine and Tyrosine
... For P. aeruginosa strain P A 0 1 , the molecular weights of the corresponding enzymes determined by the same method were : prephenate dehydrogenase, 150000; the chorismate mutase-prephenate dehydratase I aggregate, 134000 ; the second prephenate dehydratase, 76000 (CaIhoun et a/., 1973); the second ...
... For P. aeruginosa strain P A 0 1 , the molecular weights of the corresponding enzymes determined by the same method were : prephenate dehydrogenase, 150000; the chorismate mutase-prephenate dehydratase I aggregate, 134000 ; the second prephenate dehydratase, 76000 (CaIhoun et a/., 1973); the second ...
papain, a plant enzyme of biological importance
... papaya L.) manufactured from the latex of raw papaya fruits. The enzyme is able to break down organic molecules made of amino acids, known as polypeptides and thus plays a crucial role in diverse biological processes in physiological and pathological states, drug designs, industrial uses such as mea ...
... papaya L.) manufactured from the latex of raw papaya fruits. The enzyme is able to break down organic molecules made of amino acids, known as polypeptides and thus plays a crucial role in diverse biological processes in physiological and pathological states, drug designs, industrial uses such as mea ...
Investigating genotype-phenotype relationships in
... modulate the expression of several genes or even entire pathways, rendering regulatory genes attractive targets for metabolic engineering. Integration of regulatory information with genomescale models is still in its infancy, partially due to incomplete knowledge and characterization of regulation ...
... modulate the expression of several genes or even entire pathways, rendering regulatory genes attractive targets for metabolic engineering. Integration of regulatory information with genomescale models is still in its infancy, partially due to incomplete knowledge and characterization of regulation ...
The Effect of Thalidomide on Oxidation of Midazolam, S
... More than half of all pregnant women experience morning sickness. 1 With this alarming statistic, a company based in Germany called Grunenthal developed a drug for expecting mothers in the late 1950s called Thalidomide. 2 Soon after its introduction, over 10,000 babies were born with severe birth de ...
... More than half of all pregnant women experience morning sickness. 1 With this alarming statistic, a company based in Germany called Grunenthal developed a drug for expecting mothers in the late 1950s called Thalidomide. 2 Soon after its introduction, over 10,000 babies were born with severe birth de ...
npr review - Olivamine
... The molecular basis of a disease is related to dysregulation of an array of signaling molecules. With the advent of advanced molecular tools, we now know that over 500 different genes of the signaling pathways control any given disease.2 However, most currently available treatments are based on the ...
... The molecular basis of a disease is related to dysregulation of an array of signaling molecules. With the advent of advanced molecular tools, we now know that over 500 different genes of the signaling pathways control any given disease.2 However, most currently available treatments are based on the ...
please refer to anzfa`s guide to applications and proposals for a
... Written submissions are invited from interested individuals and organisations to assist FSANZ in further considering this Application. Submissions should, where possible, address the objectives of FSANZ as set out in section 18 of the FSANZ Act. Information providing details of potential costs and b ...
... Written submissions are invited from interested individuals and organisations to assist FSANZ in further considering this Application. Submissions should, where possible, address the objectives of FSANZ as set out in section 18 of the FSANZ Act. Information providing details of potential costs and b ...
Flux analysis in central carbon metabolism in plants
... I would like to thank Drs. Julie A. Dickerson (Electrical and Computer Engineering), Surya K. Mallapragada (Chemical Engineering), Martin H. Spalding (Genetics, Development, and Cell Biology), and R. Dennis Vigil (Chemical Engineering) for serving on my Program of Study committee. I am very thankful ...
... I would like to thank Drs. Julie A. Dickerson (Electrical and Computer Engineering), Surya K. Mallapragada (Chemical Engineering), Martin H. Spalding (Genetics, Development, and Cell Biology), and R. Dennis Vigil (Chemical Engineering) for serving on my Program of Study committee. I am very thankful ...
cerevisiae - Oxford Academic
... Stop codon readthrough was first detected in Escherichia coli infected with RNA phage Q and it was shown that tRNATrp 3 ACC5 stimulated the readthrough of a UGA codon at the end of the coat protein cistron that is essential for the formation of infective particles (17–19). Most of what we know ab ...
... Stop codon readthrough was first detected in Escherichia coli infected with RNA phage Q and it was shown that tRNATrp 3 ACC5 stimulated the readthrough of a UGA codon at the end of the coat protein cistron that is essential for the formation of infective particles (17–19). Most of what we know ab ...
The Genera Staphylococcus and Macrococcus
... (Roseville, Australia), is distributed by International Bioproducts, Inc. (Redmond, WA, USA), and an RPLA is available from Oxoid (Columbia, MD, USA). Molecular methods are being investigated for their usefulness in detecting staphylococcal enterotoxin. For example, Western immunoblotting has been u ...
... (Roseville, Australia), is distributed by International Bioproducts, Inc. (Redmond, WA, USA), and an RPLA is available from Oxoid (Columbia, MD, USA). Molecular methods are being investigated for their usefulness in detecting staphylococcal enterotoxin. For example, Western immunoblotting has been u ...
Interactome

In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.