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Two nearly identical terpene synthases catalyze the
Two nearly identical terpene synthases catalyze the

Chapter 5 Slides
Chapter 5 Slides

... Proteins Proteins may be "conjugated" with other chemical groups • If the non-amino acid part of the protein is important to its function, it is called a prosthetic group. • Be familiar with the terms: glycoprotein, lipoprotein, nucleoprotein, phosphoprotein, metalloprotein, hemoprotein, flavoprotei ...
DOCTORAL THESIS
DOCTORAL THESIS

... chemicals, and energy to form the final paper product, thereby creating both a higher quality and more economically viable product. Examples of enzymes presently used by the pulp and paper industry for paper product formation include xylanases, laccases, and peroxidases. The goal of the EDEN project ...
Cyclic-‐di-‐AMP: another second messenger enters the fray
Cyclic-‐di-‐AMP: another second messenger enters the fray

Solution Structure of the Tandem Acyl Carrier Protein Domains from
Solution Structure of the Tandem Acyl Carrier Protein Domains from

... determined by the amino acid sequence (Figure 5A). However, there is a small portion of the protein which shows a change of +322 Da which suggests that some of the protein may have been modified by the endogenous PPTase from the E. coli expression host. The reaction products show a distribution of m ...
The Effect of a Limited Supply of Phenylalanine, Threonine, or
The Effect of a Limited Supply of Phenylalanine, Threonine, or

Comparative genomics of unintrogressed Campylobacter coli clades 2 and 3
Comparative genomics of unintrogressed Campylobacter coli clades 2 and 3

... [56]. The OrthoMCL output was filtered to produce different lists of ortholog/paralog groups which contained: (i) tCDSs from all C. coli strains (core genome); (ii) tCDS from all the genomes of a clade; (iii) tCDSs from all the genomes of a clade and missing in the other clades; (iv) tCDSs from at l ...
Advanced Stochastic Protein Sequence Analysis
Advanced Stochastic Protein Sequence Analysis

... of various genes, predicted using bioinformatics methods, gave access to the understanding of at least parts of complex metabolic systems. Without such methods fundamental insights which are now widely accepted would not have been possible for years. Thus, the relevancy and the success of computatio ...
Development of prokaryotic cell-free systems for synthetic
Development of prokaryotic cell-free systems for synthetic

... then degrade the tagged growth-related proteins, while the key enzyme can run the pathway. This process can be achieved by engineering the strain to have protein degradation tags on growth-related proteins and periplasm-export tags on key enzymes. ...
Plant and Soil
Plant and Soil

... modification of one subunit of dinitrogenase reductase by dinitrogenase reductase ADP-ribosyltransferase ( D R A T ) . The system can be reactivated when NH~- is exhausted, by dinitrogenase reductase activating glycohydrolase ( D R A G ) which removes the inactivating group. It is fascinating that s ...
OMPROT PP2 ver4 - Plant Physiology
OMPROT PP2 ver4 - Plant Physiology

... undergo fusion, fission and rapid movements, suggesting a dynamic interaction with components of the cytoskeleton (Sheahan et al., 2004; Sheahan et al., 2005; Logan, 2010). However, many of the specific proteins that mediate such processes remain unknown. While mitochondria do play a central role in ...
Prediction of Folding, Stability and Structure of Proteins from Amino
Prediction of Folding, Stability and Structure of Proteins from Amino

... CHAPTER 1 INTRODUCTION ...
Interactions of TCA cycle enzymes and of the CcpA
Interactions of TCA cycle enzymes and of the CcpA

... formation of a metabolon facilitates the transfer of metabolites, in Bacillus subtilis, the enzymes of the TCA cycle are likely organized in multienzyme complexes. Recently, in vivo analyses suggested, that the TCA cycle enzymes malate dehydrogenase Mdh, isocitrate dehydrogenase Icd and citrate synt ...
Plant Peroxisomes: Biogenesis and Function
Plant Peroxisomes: Biogenesis and Function

... APX3 and PEX16 contain ER targeting elements that are distinct from typical signal peptide or signal anchor sequences and overlap with or are adjacent to the elements responsible for their subsequent targeting from the ER to peroxisomes (Mullen and Trelease, 2000; Karnik and Trelease, 2007). While t ...
Supplementary materials - Stanford Artificial Intelligence Laboratory
Supplementary materials - Stanford Artificial Intelligence Laboratory

... (a) Learning the regulatory program: Given a set of modules, we learned the regulatory association for each module by using the candidate expression (e-) and genotype (g-) regulators as candidate genetic regulators. As described above, the association between the genetic regulators and the expressio ...
Electrophoresis Basi..
Electrophoresis Basi..

... neutral pH’s are either basic or acidic depending upon their AA composition. Most proteins placed into basic conditions become negatively charged. Acidic conditions cause most proteins to develop a positive charge. ...
Identification of genomic features in the classification of loss
Identification of genomic features in the classification of loss

... addition, the B-SIFT algorithm calculates scores of mutation alleles based on evolutionary conservation information [3]. They used the scores to identify mutations which cause hyperactivation or gain-of-function outcomes, but our work uses not only the functional effects of mutations but also severa ...
Farnesyl diphosphate synthase, the target for nitrogen
Farnesyl diphosphate synthase, the target for nitrogen

... The mevalonate pathway of isoprenoid biosynthesis allows eukaryotic cells to convert acetyl-CoA into FDP (farnesyl diphosphate). FDP is mainly used for biosynthesis of sterols but it may also be used, either directly or after conversion into geranylgeranyl diphosphate, for protein prenylation [1]. T ...


... structure, that is, the active amino acid in their reactive site, which are serine-, cysteine-, aspartic-, and metallo-PIs (Losso, 2008). In specially, plant serine-PIs are grouped into Bovine pancreatic trypsin inhibitor (Kunitz), Pancreatic secretory trypsin inhibitor (Kazal), Streptomyces subtili ...
Cardiac mitochondrial matrix and respiratory complex - AJP
Cardiac mitochondrial matrix and respiratory complex - AJP

167 renal and small intestinal sodium
167 renal and small intestinal sodium

... membrane-transport proteins, such as the SGLT-1 or Na+/Cl symport families (Wright et al. 1992). Also, no significant overall identity was found with other cloned mammalian and non-mammalian membrane Na+-dependent and Na+-independent transport systems deposited in current databanks. Comparison of th ...
Eukaryote-Like Serine/Threonine Kinases and Phosphatases in
Eukaryote-Like Serine/Threonine Kinases and Phosphatases in

... on bacterial kinases with catalytic domains that share structural and functional homology with eukaryotic Ser/Thr kinases. These kinases are referred to herein as eSTKs to distinguish them from other prokaryotic enzymes that can also phosphorylate Ser/Thr residues (see the next section). Although ou ...
Life Inside a Microtubule
Life Inside a Microtubule

... a direct relationship between a given kinase and actin phosphorylation1. For example, Ser and Tyr residues on actin are phosphorylated in response to insulin via unknown kinases, leading to reduced DNAse I binding1 (Fig. 1). Likewise, activation of the p21-activated kinase PAK1 leads to actin phosph ...
Hydrolysis of a Series of Synthetic Peptide Substrates by the Human
Hydrolysis of a Series of Synthetic Peptide Substrates by the Human

... Biology of Picornaviruses (Urbino, Italy, 1983) (Rueckert & Wimmer, 1984) has been used in this paper. Where reference is made to papers that used the earlier nomenclature, the former names of the respective proteins are given in parentheses for ease of reference.] The genomic RNA acts as a monocist ...
Geometrical and Sequence Characteristics of
Geometrical and Sequence Characteristics of

... (Kumar and Bansal, 1996) to deduce the overall geometry of an a-helix from its local structural features, namely, local bending angles and local helix axes computed for every four consecutive Ca atoms. This window of four Ca atoms was slid over the length of the helix in steps of one Ca atom. The ge ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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