Differential Regulation of a-Lactalbumin and
... tating Glands.Total mRNAwasisolatedfrom rat mammary control of casein mRNA is suggested by removal of the gland on various days of pregnancy and lactation. Chart 8 pups during lactation; casein messenger levels are dimin shows total protein synthesized as a function of the pg of ished (Chart 9A). Wh ...
... tating Glands.Total mRNAwasisolatedfrom rat mammary control of casein mRNA is suggested by removal of the gland on various days of pregnancy and lactation. Chart 8 pups during lactation; casein messenger levels are dimin shows total protein synthesized as a function of the pg of ished (Chart 9A). Wh ...
9 The AMP-activated protein kinase: more than an energy sensor
... AMP. Thus AICA riboside has been extensively used in cells or even in vivo to activate AMPK [1,2]. However, several effects of AICA riboside, including the inhibition of liver glucose uptake and of mitochondrial respiration, are independent of AMPK [19]. In addition, intracellular ZMP accumulation h ...
... AMP. Thus AICA riboside has been extensively used in cells or even in vivo to activate AMPK [1,2]. However, several effects of AICA riboside, including the inhibition of liver glucose uptake and of mitochondrial respiration, are independent of AMPK [19]. In addition, intracellular ZMP accumulation h ...
Coordinated concentration changes of transcript and metabolites in Saccharomyces cerevisiae.
... unlike transcriptional or protein-interaction networks, consist of molecular species which chemically interconvert. As a result, metabolites that are only distantly related in terms of the underlying pathways can show high levels of correlation [18]. This is especially true in the case of global per ...
... unlike transcriptional or protein-interaction networks, consist of molecular species which chemically interconvert. As a result, metabolites that are only distantly related in terms of the underlying pathways can show high levels of correlation [18]. This is especially true in the case of global per ...
BIF CH4 5th proofs.qxd
... terms “homology” and “similarity” are sometimes used interchangeably, but each has a distinct meaning. Similarity is simply a descriptive term telling you that the sequences in question show some degree of match. Homology, in contrast, has distinct evolutionary and biological implications. In the mo ...
... terms “homology” and “similarity” are sometimes used interchangeably, but each has a distinct meaning. Similarity is simply a descriptive term telling you that the sequences in question show some degree of match. Homology, in contrast, has distinct evolutionary and biological implications. In the mo ...
Isoelectric point prediction from the amino acid sequence of a protein
... ' additionally grant to the Rochester Institute of Technology Digital Media Library (RIT DML) the non-exclusive license to archive and provide electronic access to my thesis or dissertation in whole or in part in all forms of media in perpetuity. I understand that my work, in addition to its bibliog ...
... ' additionally grant to the Rochester Institute of Technology Digital Media Library (RIT DML) the non-exclusive license to archive and provide electronic access to my thesis or dissertation in whole or in part in all forms of media in perpetuity. I understand that my work, in addition to its bibliog ...
Formation of Monoterpenes in Antirrhinum majus
... Characterization of FPPS and GGPPS activities, and in some cases of the purified homodimeric enzymes, has been reported from numerous plant sources as well as from animals and microorganisms. Recently, genes encoding FPPS and GGPPS have been isolated from a diverse range of plant species in which th ...
... Characterization of FPPS and GGPPS activities, and in some cases of the purified homodimeric enzymes, has been reported from numerous plant sources as well as from animals and microorganisms. Recently, genes encoding FPPS and GGPPS have been isolated from a diverse range of plant species in which th ...
SUC1 and SUC2: two sucrose transporters from Arabidopsis
... An important, most likely essential step for the long distance transport of sucrose in higher plants is the energy-dependent, uncoupler-sensiUve loading into phloem cells via a sucrose-H+ symporter. This paper describes functional expression in Saccharomyces cerevisiae of two cDNAs encoding energy-d ...
... An important, most likely essential step for the long distance transport of sucrose in higher plants is the energy-dependent, uncoupler-sensiUve loading into phloem cells via a sucrose-H+ symporter. This paper describes functional expression in Saccharomyces cerevisiae of two cDNAs encoding energy-d ...
Effects of Molecular Crowding on Binding Affinity of Dihydrofolate to
... one active site, specific for NADPH and DHF 1. R67, on the other hand has one binding site that binds both NADPH and DHF ligands 1. The enzyme efficiency of DHFR changes when DHF interacts with other molecules. DHF Interaction with Osmolytes and Solutes According to Grubbs’s model (Appendix B), with ...
... one active site, specific for NADPH and DHF 1. R67, on the other hand has one binding site that binds both NADPH and DHF ligands 1. The enzyme efficiency of DHFR changes when DHF interacts with other molecules. DHF Interaction with Osmolytes and Solutes According to Grubbs’s model (Appendix B), with ...
Structural and Functional Studies on Proteinaceous Metallocarboxypeptidase Inhibitors Joan López Arolas
... cysteine enzymes and the aspartic protease cathepsin D via different domains (Lenarcic & Turk, 1999). For a few inhibitors, functions other than protease blockage have also been found such as growth factor activities, receptor clearance signaling or involvement in carcinogenesis (Clawson, 1996). The ...
... cysteine enzymes and the aspartic protease cathepsin D via different domains (Lenarcic & Turk, 1999). For a few inhibitors, functions other than protease blockage have also been found such as growth factor activities, receptor clearance signaling or involvement in carcinogenesis (Clawson, 1996). The ...
An investigation of the zinc binding characteristics of the RING finger
... bind two Zn2+ ions, coordinated by eight conserved cysteine or histidine residues, typically forming a C3HC4 motif, although a number of other possibilities including C4C4 and C4HC3 have been reported. Sequence alignments suggest that the RBBP6 RING is either a C4C4 or possibly a novel C3NC4 RING. S ...
... bind two Zn2+ ions, coordinated by eight conserved cysteine or histidine residues, typically forming a C3HC4 motif, although a number of other possibilities including C4C4 and C4HC3 have been reported. Sequence alignments suggest that the RBBP6 RING is either a C4C4 or possibly a novel C3NC4 RING. S ...
Comparison of Genes Encoding Enzymes of Sterol Biosynthesis
... Sterols are ubiquitous membrane lipid components found in eukaryotic organisms. Sterols are known to serve novel functions in eukaryotes. Sterol biosynthesis pathways differ among fungi, plants and vertebrates. Lipid biosynthesis has been extensively studied in the model yeast Saccharomyces cerevisi ...
... Sterols are ubiquitous membrane lipid components found in eukaryotic organisms. Sterols are known to serve novel functions in eukaryotes. Sterol biosynthesis pathways differ among fungi, plants and vertebrates. Lipid biosynthesis has been extensively studied in the model yeast Saccharomyces cerevisi ...
Get PDF - Wiley Online Library
... N-terminally longer by 158 amino acids relative to the methionine which aligns with the first methionine of the published eIF4GI sequence (Gradi et al., 1998). We suspected that the original cDNA clone of eIF4GI (Yan et al., 1992) contained an intron, because the similarity of this clone to that of ...
... N-terminally longer by 158 amino acids relative to the methionine which aligns with the first methionine of the published eIF4GI sequence (Gradi et al., 1998). We suspected that the original cDNA clone of eIF4GI (Yan et al., 1992) contained an intron, because the similarity of this clone to that of ...
Transporters of nucleotide sugars, nucleotide
... mutant transporter proteins followed by reconstitution into liposomes should allow determination of structural motifs required for membrane insertion, nucleotide recognition, and specific sugar translocation. Studies of the yeast GDPase, which plays a pivotal role in the antiport mechanism for GDP-m ...
... mutant transporter proteins followed by reconstitution into liposomes should allow determination of structural motifs required for membrane insertion, nucleotide recognition, and specific sugar translocation. Studies of the yeast GDPase, which plays a pivotal role in the antiport mechanism for GDP-m ...
Protein Structure Hierarchy
... backbone, sticks, spacefill, ball & stick, ribbons, strands and cartoons) from the “pull-down” menus. Think about the advantages and disadvantages of these different representations are you see them. Choosing the best way to view a structural detail can only be learned through experience. ...
... backbone, sticks, spacefill, ball & stick, ribbons, strands and cartoons) from the “pull-down” menus. Think about the advantages and disadvantages of these different representations are you see them. Choosing the best way to view a structural detail can only be learned through experience. ...
Protein Profile Characterization of Donkey Milk
... g/100 g of total fatty acids, when compared with ruminant species milks, in which the contents of the above mentioned Polyunsaturated Fatty Acids are always lower. To increase the total fat content in donkey milk, clinical studies [17, 35] suggested to enrich donkey milk with medium-chain triglyceri ...
... g/100 g of total fatty acids, when compared with ruminant species milks, in which the contents of the above mentioned Polyunsaturated Fatty Acids are always lower. To increase the total fat content in donkey milk, clinical studies [17, 35] suggested to enrich donkey milk with medium-chain triglyceri ...
Yeast lipid metabolism at a glance
... enriched in PS, whereas cardiolipin (CL) and phosphatidylglycerol (PG) are predominantly found in mitochondria (Zinser et al., 1991). Besides PL, sphingolipids (SL) and sterols also contribute to the membrane architecture. SL are especially found in the plasma membrane, but also in other organelles ...
... enriched in PS, whereas cardiolipin (CL) and phosphatidylglycerol (PG) are predominantly found in mitochondria (Zinser et al., 1991). Besides PL, sphingolipids (SL) and sterols also contribute to the membrane architecture. SL are especially found in the plasma membrane, but also in other organelles ...
(1) Giycophorin was incorporated into large
... suits of these experiments are summarized in Table I. Comparison of the permeability data of the glycophorin-containing vesicles with the pure lipid vesicles, clearly shows that incorporation of glycophorin induces a largely increased permeability for glucose as well as for raffinose. This confirms ...
... suits of these experiments are summarized in Table I. Comparison of the permeability data of the glycophorin-containing vesicles with the pure lipid vesicles, clearly shows that incorporation of glycophorin induces a largely increased permeability for glucose as well as for raffinose. This confirms ...
Lactobacillus plantarum - UEF Electronic Publications
... Lactic acid bacteria (LAB) are a heterogeneous group of organisms found in a wide range of environmental niches due to their large adaptation capacity. They are responsible for the fermentation of many fermented food and feed products because they can transform sugars into organic acids and decrease ...
... Lactic acid bacteria (LAB) are a heterogeneous group of organisms found in a wide range of environmental niches due to their large adaptation capacity. They are responsible for the fermentation of many fermented food and feed products because they can transform sugars into organic acids and decrease ...
Multiple Lines of Evidence Localize Signaling
... cytosol to enter mitochondria, it also acts as a barrier for molecules to leave mitochondria. Thus, the outer mitochondrial membrane may also contain proteins involved in signal transduction and mediating retrograde signals from the mitochondrion to the nucleus or even from the mitochondrion to the ...
... cytosol to enter mitochondria, it also acts as a barrier for molecules to leave mitochondria. Thus, the outer mitochondrial membrane may also contain proteins involved in signal transduction and mediating retrograde signals from the mitochondrion to the nucleus or even from the mitochondrion to the ...
FIST/HIPK3: a Fas/FADD-interacting Serine/Threonine Kinase that
... named the protein FIST for Fas-interacting Ser/Thr kinase) encoded by the insert of the various clones all strongly interacted with the complete cytoplasmic domain of Fas but not with TNFR1, lamin A, LDL receptor, or poly Ig receptor (not shown). An EMBL/GenBank/DDBJ search revealed that the sequenc ...
... named the protein FIST for Fas-interacting Ser/Thr kinase) encoded by the insert of the various clones all strongly interacted with the complete cytoplasmic domain of Fas but not with TNFR1, lamin A, LDL receptor, or poly Ig receptor (not shown). An EMBL/GenBank/DDBJ search revealed that the sequenc ...
Amino Acids
... • Collagen superfamily of proteins include > 20 collagen types, as well as additional proteins that have collagenlike domains. • The 3 polyp. α-chains are held together by H-bonds b/w the chains. • Variations in aa sequence of α-chains result in structural components that are ~ the same size (~ 1000 ...
... • Collagen superfamily of proteins include > 20 collagen types, as well as additional proteins that have collagenlike domains. • The 3 polyp. α-chains are held together by H-bonds b/w the chains. • Variations in aa sequence of α-chains result in structural components that are ~ the same size (~ 1000 ...
Contributions of direct incorporation from diet and microbial amino
... & Martinez del Rio 2010). While these experiments demonstrate that routing produces results that deviate from expectations based on mixing models, they were not able to characterize the isotopic patterns among specific amino acids that contribute to routing because they were conducted at the bulk ti ...
... & Martinez del Rio 2010). While these experiments demonstrate that routing produces results that deviate from expectations based on mixing models, they were not able to characterize the isotopic patterns among specific amino acids that contribute to routing because they were conducted at the bulk ti ...
dbPSP: a curated database for protein phosphorylation sites in
... its critical roles in various cellular processes such as signal transduction. Thus, an integrative data resource of the prokaryotic phosphorylation will be useful for further analysis. In this study, we presented a curated database of phosphorylation sites in prokaryotes (dbPSP, Database URL: http:/ ...
... its critical roles in various cellular processes such as signal transduction. Thus, an integrative data resource of the prokaryotic phosphorylation will be useful for further analysis. In this study, we presented a curated database of phosphorylation sites in prokaryotes (dbPSP, Database URL: http:/ ...
General principles of cellular organization in the genome
... investigations, to which I contributed most substantially. In order to study basic principles of bacterial proteome organization, we used tandem affinity purification followed by mass spectrometric analysis to investigate protein complexes in a proteome-wide screen. The analysis revealed 62 homomult ...
... investigations, to which I contributed most substantially. In order to study basic principles of bacterial proteome organization, we used tandem affinity purification followed by mass spectrometric analysis to investigate protein complexes in a proteome-wide screen. The analysis revealed 62 homomult ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.