Salinity Response in Chloroplasts: Insights from Gene
... products, the enhancement of reactive oxygen species (ROS) scavenging, phytohormone regulation, and cell structure modulation [2]. Chloroplasts are organelles for photosynthesis. Chloroplasts also participate in many other important metabolic processes, including the biosynthesis of amino acids, vit ...
... products, the enhancement of reactive oxygen species (ROS) scavenging, phytohormone regulation, and cell structure modulation [2]. Chloroplasts are organelles for photosynthesis. Chloroplasts also participate in many other important metabolic processes, including the biosynthesis of amino acids, vit ...
Biomarker discovery for psychiatric disorders
... psychiatric disorders in the industrialized world with an estimated lifetime prevalence ranging from 14.5% to 28.8% in Europe and in the USA (Jacobi et al., 2004; Kessler et al., 2005). Twin and family studies have revealed a 30-40% heritability of anxiety disorders (Hettema et al., 2001), suggestin ...
... psychiatric disorders in the industrialized world with an estimated lifetime prevalence ranging from 14.5% to 28.8% in Europe and in the USA (Jacobi et al., 2004; Kessler et al., 2005). Twin and family studies have revealed a 30-40% heritability of anxiety disorders (Hettema et al., 2001), suggestin ...
Proteolytic processing in the secretory pathway of Aspergillus niger
... proteases. A brief explanation of these four groups is given here; a more elaborate description is given by van den Hombergh (1996). Each group has a different proteolytic mechanism and therefore different enzymatic characteristics and inhibitors. The cysteine proteases are a rare group of proteases ...
... proteases. A brief explanation of these four groups is given here; a more elaborate description is given by van den Hombergh (1996). Each group has a different proteolytic mechanism and therefore different enzymatic characteristics and inhibitors. The cysteine proteases are a rare group of proteases ...
Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine
... selection of chemical scaffolds, which makes it easier for bacterial pathogens to quickly develop resistance against new drug derivatives. This recurrent problem of multiple drug resistance implies a constant need to search for novel microbial targets and to modulate their activity using artificial ...
... selection of chemical scaffolds, which makes it easier for bacterial pathogens to quickly develop resistance against new drug derivatives. This recurrent problem of multiple drug resistance implies a constant need to search for novel microbial targets and to modulate their activity using artificial ...
1 Causality, Transfer Entropy and Allosteric
... because of its relation to information flow and allosteric communication. Allosteric communication is the process in which action at one site of a protein is transmitted to another site at which the protein performs its activity. Protein-protein and protein-DNA interactions, drug action and all proc ...
... because of its relation to information flow and allosteric communication. Allosteric communication is the process in which action at one site of a protein is transmitted to another site at which the protein performs its activity. Protein-protein and protein-DNA interactions, drug action and all proc ...
Predicting the sidechain dihedral angle distributions
... when considering large proteins. In addition, molecular mechanics force fields directly sample the experimentally measured backbone and side-chain dihedral angle distributions using knowledge-based potentials, such as CHARMM-CMAP14 and v-CMAP,15 or AmberILDN.16 Thus, the molecular mechanics force fi ...
... when considering large proteins. In addition, molecular mechanics force fields directly sample the experimentally measured backbone and side-chain dihedral angle distributions using knowledge-based potentials, such as CHARMM-CMAP14 and v-CMAP,15 or AmberILDN.16 Thus, the molecular mechanics force fi ...
Characterization and the role of carbonic anhydrase
... characterized.This was the first time that gamma-carbonic anhydrase (CA) activity was observed in CcmM from a mesophilic cyanobacteria, a protein that was initially considered to be catalytically inactive. Using molecular and biophysical techniques, they identified the CA activity in the whole cell ...
... characterized.This was the first time that gamma-carbonic anhydrase (CA) activity was observed in CcmM from a mesophilic cyanobacteria, a protein that was initially considered to be catalytically inactive. Using molecular and biophysical techniques, they identified the CA activity in the whole cell ...
mammalian hibernation: biochemical adaptation
... of ATP production needed to support their shivering is supplied by aerobic sugar oxidation in muscle using the massive stores of honey that the colony laid down from summer foraging. Hence, honeybees use a social solution to winter warmth. Another futile form of ATP turnover that supports thermogene ...
... of ATP production needed to support their shivering is supplied by aerobic sugar oxidation in muscle using the massive stores of honey that the colony laid down from summer foraging. Hence, honeybees use a social solution to winter warmth. Another futile form of ATP turnover that supports thermogene ...
Enzymatic activation of sulfur for incorporation into biomolecules in
... inactivated (Zheng et al., 1998). The iscS gene of A. vinelandii is located at the 5 0 end of an operon, which also contains iscU, iscA, hscB, hscA and fdx; this type of operon is widespread in nature (Zheng et al., 1998) and crucial for general iron sulfur cluster (isc) biosynthesis in many organis ...
... inactivated (Zheng et al., 1998). The iscS gene of A. vinelandii is located at the 5 0 end of an operon, which also contains iscU, iscA, hscB, hscA and fdx; this type of operon is widespread in nature (Zheng et al., 1998) and crucial for general iron sulfur cluster (isc) biosynthesis in many organis ...
SNAREs
... been the apparent lack of specificity among many SNARE–SNARE associations. This lack of specificity is particularly apparent in in vitro mixing experiments using bacterially expressed mammalian as well as yeast SNARE proteins (Yang et al. 1999; Fasshauser et al. 1999; Tsui and Banfield 2000). Recent ev ...
... been the apparent lack of specificity among many SNARE–SNARE associations. This lack of specificity is particularly apparent in in vitro mixing experiments using bacterially expressed mammalian as well as yeast SNARE proteins (Yang et al. 1999; Fasshauser et al. 1999; Tsui and Banfield 2000). Recent ev ...
Structure and Function of Large Bio Molecules
... An immense variety of polymers can be built from a small number of monomers. • Each cell has thousands of different kinds of macromolecules. • Macromolecules vary among cells of the same individual. They vary more among unrelated individuals of a species, and even more between species. • This divers ...
... An immense variety of polymers can be built from a small number of monomers. • Each cell has thousands of different kinds of macromolecules. • Macromolecules vary among cells of the same individual. They vary more among unrelated individuals of a species, and even more between species. • This divers ...
Biochemical, biophysical and interaction studies of the stress
... Designs and Patents Act 1988 (as amended) and regulations issued under it or, where appropriate, in accordance with licensing agreements which the University has from time to time. This page must form part of any such copies made. iii. The ownership of certain Copyright, patents, designs, trademarks ...
... Designs and Patents Act 1988 (as amended) and regulations issued under it or, where appropriate, in accordance with licensing agreements which the University has from time to time. This page must form part of any such copies made. iii. The ownership of certain Copyright, patents, designs, trademarks ...
Turnip yellow mosaic virus RNA can be separated into two distinct
... It was sometimes necessary to pass fraction 3 through a second Ultrogel column (0.8 cm x 60 cm) to eliminate traces of heavy RNA, but no light RNA contamination of fraction 1 could be detected even if 80 pg of RNA was loaded on the gel. Hence, fraction 1 was generally used without further purificati ...
... It was sometimes necessary to pass fraction 3 through a second Ultrogel column (0.8 cm x 60 cm) to eliminate traces of heavy RNA, but no light RNA contamination of fraction 1 could be detected even if 80 pg of RNA was loaded on the gel. Hence, fraction 1 was generally used without further purificati ...
The Amino Acid Sequences of the Myelin
... brain mRNA (10). Presumably, these polypeptides, when glycosylated in vivo, co-migrate on SDS PAGE as the single, characteristically broad band (Mr 100,000) that corresponds to native MAG (40). The precise structural differences between the two MAG proteins are not known. Peptide maps of the two pol ...
... brain mRNA (10). Presumably, these polypeptides, when glycosylated in vivo, co-migrate on SDS PAGE as the single, characteristically broad band (Mr 100,000) that corresponds to native MAG (40). The precise structural differences between the two MAG proteins are not known. Peptide maps of the two pol ...
Title
... http://media.hsls.pitt.edu/media/molbiovideos/metacore1.swf http://media.hsls.pitt.edu/media/molbiovideos/metacore2.swf http://www.hsls.pitt.edu/molbio ...
... http://media.hsls.pitt.edu/media/molbiovideos/metacore1.swf http://media.hsls.pitt.edu/media/molbiovideos/metacore2.swf http://www.hsls.pitt.edu/molbio ...
EP 1790660 B1
... [0026] In a fifth approach to heterologous expression, two or more (e.g. 3, 4, 5, 6 or more) proteins of the invention are expressed as a single hybrid protein. It is preferred that no non-Neisserial fusion partner (e.g. GST or poly-His) is used. [0027] This offers two advantages. Firstly, a protein ...
... [0026] In a fifth approach to heterologous expression, two or more (e.g. 3, 4, 5, 6 or more) proteins of the invention are expressed as a single hybrid protein. It is preferred that no non-Neisserial fusion partner (e.g. GST or poly-His) is used. [0027] This offers two advantages. Firstly, a protein ...
Energy Calculations for 4-Hydroxy-3
... Minimization of the Hetero compound All of the calculated energy terms for the hetero compound, 4-Hydroxy-3-MethylButyl Diphosphate, changed when a MM2 energy minimization was performed on the hetero compound. Not only do the values in Table 1 reflect the differences in energy of the two structures ...
... Minimization of the Hetero compound All of the calculated energy terms for the hetero compound, 4-Hydroxy-3-MethylButyl Diphosphate, changed when a MM2 energy minimization was performed on the hetero compound. Not only do the values in Table 1 reflect the differences in energy of the two structures ...
Substrate specificity of the periplasmic dipeptide
... substrates containing up to about six amino acid residues. Opp is encoded by five genes, oppABCDF (Hiles et al., 1987), and is a member of the periplasmicbinding-protein-dependent family of traffic ATPases (Ames et al., 1990). The crystal structure of the binding protein, OppA, has been reported (Ta ...
... substrates containing up to about six amino acid residues. Opp is encoded by five genes, oppABCDF (Hiles et al., 1987), and is a member of the periplasmicbinding-protein-dependent family of traffic ATPases (Ames et al., 1990). The crystal structure of the binding protein, OppA, has been reported (Ta ...
Getting to grips with the plant metabolic network
... genome.ad.jp/ [23]), though the only specific maps for higher plants are for Arabidopsis thaliana (thale cress) and Oryza sativa (rice)}, and searching for each enzyme in the database BRENDA {BRaunschweig ENzyme DAtabase (http://www.brenda.unikoeln.de/ [24])} for organism-specific literature. The go ...
... genome.ad.jp/ [23]), though the only specific maps for higher plants are for Arabidopsis thaliana (thale cress) and Oryza sativa (rice)}, and searching for each enzyme in the database BRENDA {BRaunschweig ENzyme DAtabase (http://www.brenda.unikoeln.de/ [24])} for organism-specific literature. The go ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.